Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| W691L | FKS1 | C. auris | Validated | CRISPR/Cas9 Gene Editing | 37222585 |
W691L mutation in the Fks1 enzyme alters drug-enzyme interaction, reducing echinocandin susceptibility. | 2 |