Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| W297R | PDR1 | C. glabrata | Validated | qRT-PCR | 27744635 |
W297R gain-of-function mutation enhances efflux pump expression (CgCDR1/2, CgSNQ2), lowering intracellular azole levels and conferring resistance | 2 |