Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| W286del | ERG6 | C. glabrata | Validated | Sterol Analysis | 30455247 |
The mutation W286del depletes ergosterol and accumulates zymosterol, causing amphotericin B resistance. | 2 |