Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| W219C | ERG3 | C. albicans | Validated | Chitin estimation, Biofilm formation assay | 31762516 |
W219C mutation disrupts sterol metabolism, preventing toxic sterol formation and contributing to azole resistance. | 2 |