Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| V162A | GWT1 | C. albicans | Validated | CRISPR-based mutagenesis | 31611349 |
V162A mutation alters Gwt1 enzyme function in the GPI biosynthesis pathway, disrupting MGX binding and increasing resistance. | 2 |