Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T985del | MRR1 | C. dubliniensis | Validated | Expression of Mutated MRR1 Alleles in C. albicans | 18809934 |
T985 deletion in MRR1 activates Mrr1p, overexpressing MDR1, increasing efflux, and causing fluconazole resistance. | 2 |