Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T83A | MRR2 | C. albicans | Validated | Gene expression | 31705810 |
The T83A mutation increases the expression of Cdr1, boosting efflux pump activity and reducing intracellular drug concentration, causing resistance. | 2 |