Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T588A | PDR1 | C. glabrata | Validated | qRT-PCR | 19148266 27744635 |
T588A is a gain-of-function mutation that activates CgPdr1p, leading to the upregulation of CgCDR1 and CgCDR2 conferring resistance | 2 |