Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T470N | MRR2 | C. albicans | Validated | qRT-PCR | 26404130 |
The T470N mutation in MRR1 enhances drug resistance by increasing CDR1 expression, which leads to a four-fold increase in fluconazole resistance | 2 |