Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T374I | MRR1 | C. dubliniensis | Validated | Expression of Mutated MRR1 Alleles in C. albicans | 18809934 |
T374I in MRR1 activates Mrr1p, overexpressing MDR1 and enhancing efflux, causing resistance. | 2 |