Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T292K | PDR1 | C. glabrata | Validated | qRT-PCR | 35577042 |
T292K gain-of-function mutation enhances azole resistance by upregulating CgCDR1 and CgCDR2 efflux pumps, increasing drug export, fitness, and virulence | 2 |