Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| T220L | ERG11 | C. albicans | Validated | Efflux pump activity | 28065893 37026059 |
The T220L mutation in ERG11 reduces the enzyme's affinity for fluconazole (FLC), contributing to resistance. | 2 |