Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| S942F | PDR1 | C. glabrata | Validated | qRT-PCR | 35577042 |
S942F mutation in PDR1 increases CgCDR1 expression, enhancing azole efflux and reducing drug susceptibility. | 2 |