Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| S663F | FKS2 | C. glabrata | Validated | Animal study; PCR assay | 22948870;24829248 |
S663F mutation alters the 1,3-β-D-glucan synthase complex, reducing echinocandin binding and causing resistance | 2 |