Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| S656P | FKS1 | C. parapsilosis | Validated | site directed mutagenesis | 36440795 |
64-fold increase in mic of all echinocandins (pan-echinocandin resistance) when mutation was introduced in susceptible strain | 2 |