Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| S316I | PDR1 | C. glabrata | Validated | Site-directed mutagenesis; qRT-PCR | 19148266 27020939 35577042 |
S316I gain-of-function mutation in CgPDR1 leads to overexpression of CgCDR1, conferring azole resistance. | 2 |