Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| S1037L | MRR1 | C. albicans | Validated | mRNA Expression Analysis; Efflux Pump Activity | 24051054 29434708 |
The S1037L mutation in MRR1 increases MDR1 expression, reducing azole efficacy and contributing to cross-resistance. | 2 |