Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| R873T | MRR1 | C. albicans | Validated | qRT-PCR | 18577180 |
The gain-of-function R873T enhances the transcription factor's activity, resulting in MDR1 overexpression and contributing to multidrug resistance. | 2 |