Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| R656G | FKS1 | C. tropicalis | Validated | Expression in S. cerevisiae | 33468487 |
R656G alters enzyme structure, reducing azole binding affinity and leading to resistance. | 2 |