Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| R250K | PDR1 | C. glabrata | Validated | Gene Expression Analysis | 35577042 |
The R250K mutation in PDR1 causes overexpression of efflux pump genes like CDR1, CDR2, and SNQ2, contributing to resistance. | 2 |