Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| R1377stop | FKS2 | C. glabrata | Validated | Kinetic analysis | 19546367 |
R1377stop mutation causes a truncated Fks2p, reducing glucan synthase function and leading to echinocandin resistance. | 2 |