Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| R135I | ERG3 | C. parapsilosis | Validated | sterol analysis | 28196695 |
mutation cause erg3 protein structure disfunction resulting in absense of ergosterol and formation of sterol intermediates Ergosta-7,22-dienol and Ergosta-7-enol | 2 |