Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| Q386K | MSH2 | C. glabrata | Validated | Construction of strains with specific MSH2 alleles | 29610199 |
Q386K mutation partially impairs its DNA mismatch repair function, increasing mutation rates, causing resistance | 2 |