Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| P98S | ERG11 | C. albicans | Validated | Gene expression analysis | 29136186 |
The P98S mutation in ERG11 reduces azole binding affinity by altering the enzyme's structure, contributing to azole resistance. | 2 |