Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| P927S | PDR1 | C. glabrata | Validated | Ectopic Expression | 29464833 |
P927S is a gain-of-function mutation that enhances the expression of efflux pumps, leading to azole resistance. | 2 |