Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| P822L | PDR1 | C. glabrata | Validated | Disruption and Reintroduction of CgPDR1 | 18312269 |
P822L gain-of-function mutation increases CgSNQ2 expression, enhancing drug efflux and contributing to resistance. | 2 |