Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| P236S | ERG11 | C. albicans | Validated | Structural Prediction | 31923309 |
The P236S destabilizes the Erg11p protein, altering its structure and reducing the binding affinity of azole drugs, leading to reduced susceptibility to azole drugs. | 2 |