Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| N647T | MRR1 | C. auris | Validated | Site-directed mutagenesis, qRT-Pcr | 35343781 |
N647T gain-of-function mutation upregulates MDR1, enhancing drug efflux conferring resistance. | 2 |