Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| N435V | ERG11 | C. albicans | Validated | Heterologous expression in Saccharomyces cerevisiae | 23480635 |
N435V alters Erg11 structure, reducing azole binding affinity conferring resistance. | 2 |