Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| N1240D | CDR1 | C. albicans | Validated | ATPase Activity Assay | 30348662 |
N1240D mutation alters efflux pump activity, enhancing fluconazole transport while reducing R6G efflux, causing resistance | 2 |