Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L979E | TAC1 | C. albicans | Validated | Comparative Proteomic Analysis; Disruption Studies | 21136999 |
L979E mutation in TAC1 increases CDR1 and CDR2 expression, enhancing azole efflux and resistance | 2 |