Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L347F | PDR1 | C. glabrata | Validated | qRT-PCR | 19196495 |
L347F is a gain-of-function mutation that activates CgPdr1p, leading to increased ABC transporter expression and azole resistance | 2 |