Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L341del | ERG6 | C. glabrata | Validated | Sterol analysis, DNA fingerprinting | 30455247 |
L341del mutation leads to a truncated, non-functional C-24 methyltransferase, disrupting ergosterol biosynthesis, and conferring resistance | 2 |