Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L328F | PDR1 | C. glabrata | Validated | qRT-PCR | 19148266 |
L328F is a gain-of-function mutation that upregulates ABC transporters, enhancing azole efflux and resistance. | 2 |