Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L193R | ERG3 | C. albicans | Validated | Sterol Analysis | 22678731 |
L193R reduces ergosterol production, causing resistance to azoles and amphotericin B, and impairs hyphal growth | 2 |