Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| L107S | ERG2 | C. kefyr | Validated | Sterol analyses using gas chromatography | 37358415 |
The L107S mutation in ERG2 disrupts its function, eliminating ergosterol synthesis and conferring amphotericin B resistance. | 2 |