Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| K884E | MRR1 | C. albicans | Validated | RT-PCR | 24051054 |
K884E mutation in MRR1 increases MDR1 expression, leading to more efflux pumps, contributing to azole resistance | 2 |