Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| I471T | ERG11 | C. albicans | Validated | Site-directed mutagenesis | 11036010 |
I471T mutation in Erg11 alters enzyme structure, reducing azole binding and increasing resistance | 2 |