Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| G547R | CDR1 | C. albicans | Validated | ATPase Activity Assay | 30348662 |
G547R mutation in CDR1 disrupts the efflux pump's structure, hindering FK506 cotransport, causing resistance. | 2 |