Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| G348A | PDR1 | C. glabrata | Validated | Integrative Transformation | 20547810 |
G348A gain-of-function mutation increases its expression and upregulates efflux pumps, leading to fluconazole resistance. | 2 |