Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| F559S | PDR1 | C. glabrata | Validated | Molecular Analysis | 36294562 |
F559S mutation leads to overexpression of efflux pumps like CgCDR1 and CgCDR2, causing fluconazole resistance. | 2 |