Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| E818K | PDR1 | C. glabrata | Validated | RT-qPCR | 30658200 |
E818K mutation enhances the expression of efflux pumps, increasing the export of azole drugs from the fungal cell, causing resistance. | 2 |