Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| D987-I998del | MRR1 | C. dubliniensis | Validated | Expression of Mutated MRR1 Alleles in C. albicans | 18809934 |
D987-I998 deletion in MRR1 leads to overexpression of the MDR1, enhancing efflux pump activity resulting in resistance. | 2 |