Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| A880E | MRR1 | C. albicans | Validated | MDR1 Promoter Activity Assay | 18577180 |
A880E mutation constitutively activates MDR1, increasing drug efflux and fluconazole resistance. | 2 |