Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| A643T | UPC2 | C. albicans | Validated | Site-directed mutagenesis, qRT-PCR | 22923048 |
A643T in UPC2 upregulates ERG11, increasing ergosterol synthesis and fluconazole resistance. | 2 |