Association of mutation to drug resistance
| Mutation | Gene | Species | Validation status | Validation technique(s) | Validation reference(s) | Resistance mechanism(s) | Validation score |
|---|---|---|---|---|---|---|---|
| A640V | TAC1 | C. auris | Validated | Biofilm formation assay, In Vitro Competitive Growth Assay | 19148266 27744635 |
A640V mutation in Tac1B enhances Cdr1 efflux pump expression, reducing intracellular fluconazole concentration and conferring resistance | 2 |