Browse Results

Mutations associated with antifungal drug resistance in Candida species

Strain	Species	Isolate type	Gene	Mutation	Type of mutations	UniProt ID	Protein length	Structure ID (PDB/Alpha fold/Model)	Sequence & structure	Drug resistance (MIC in mg/L)	Year of study	PMID
DUMC136	C. albicans	Clinical isolate	ERG11	K128T, Y132H, F145L	Multiple substitution	P10613	528	5V5Z		Fluconazole (>61.254)	1999	10223930
B59626	C. albicans	Clinical isolate	ERG11	K128T, A149V	Double substitution	P10613	528	5V5Z		Fluconazole (>64), Itraconazole (1)	1999	10537192
B59630	C. albicans	Clinical isolate	ERG11	K128T, A149V	Double substitution	P10613	528	5V5Z		Fluconazole (64)	1999	10537192
C26	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Fluconazole (>128), Itraconazole (>2)	1999	10537192
C40	C. albicans	Clinical isolate	ERG11	Y132H, G464S, R467K	Multiple substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (1)	1999	10537192
J913004/1	C. albicans	Clinical isolate	ERG11	K128T, V452A, G464S	Multiple substitution	P10613	528	5V5Z		Fluconazole (64), Itraconazole (1)	1999	10537192
NCPF 3363	C. albicans	Clinical isolate	ERG11	Y132H, S279F, G465S	Multiple substitution	P10613	528	5V5Z		Fluconazole (32), Itraconazole (2)	1999	10537192
Darlington (ATCC64124)	C. albicans	Clinical isolate	ERG11	F72L, Y132H	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1	Structure not available	Fluconazole (>128), Ketoconazole (32), Itraconazole (>4)	1999	10537193
NFI 2007	C. albicans	Clinical isolate	ERG11	F126L, S405F, V437I	Multiple substitution	Q9P4W0	528	AF-Q9P4W0-F1	Structure not available	Fluconazole (32), Ketoconazole (1)	1999	10537193
NFI 2013	C. albicans	Clinical isolate	ERG11	Y132H, F449L	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1	Structure not available	Fluconazole (>128), Ketoconazole (0.5), Itraconazole (>4)	1999	10537193
NFI 2021	C. albicans	Clinical isolate	ERG11	K143E, T229A	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128), Ketoconazole (0.25), Itraconazole (>1)	1999	10537193
isolate 13	C. albicans	Clinical isolate	ERG11	R467K	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (32)	1999	10579098
Darlington strain (pDarERG11(NCPF3310))	C. albicans	Laboratory strain	ERG11	Y132H, I471T	Double substitution	P10613	528	5V5Z		Fluconazole (128)	2000	11036010
1619	C. albicans	Clinical isolate	ERG11	G307S	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
2257	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
2307	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
2339	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
2440	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
2500	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
3119	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
3120	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
3184	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
3281	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
3731	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
3733	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
3795	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
4380	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
4617	C. albicans	Clinical isolate	ERG11	T229A, F449S	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
4639	C. albicans	Clinical isolate	ERG11	T229A, F449S	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2001	11557454
5052	C. albicans	Clinical isolate	ERG11	V437I, D446N	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2001	11557454
5108	C. albicans	Clinical isolate	ERG11	V437I, G464S	Double substitution	P10613	528	5V5Z	Structure not available	Fluconazole (64)	2001	11557454
R3.8	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (64)	2002	11864952
R5.1	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (64)	2002	11864952
S2.2	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (64)	2002	11864952
3946(Patient1)	C. dubliniensis	Clinical isolate	ERG11	F126L, T199A, R210G	Multiple substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (64)	2002	12019078
4380(Patient1)	C. dubliniensis	Clinical isolate	ERG11	G464S	Single substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (64)	2002	12019078
4572(Patient 2)	C. dubliniensis	Clinical isolate	ERG11	S113F, G289D	Double substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (64)	2002	12019078
4713(Patient1)	C. dubliniensis	Clinical isolate	ERG11	G464S	Single substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (64)	2002	12019078
4806(Patient1)	C. dubliniensis	Clinical isolate	ERG11	F148L, G307A, P515S	Multiple substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (64)	2002	12019078
4807(Patient1)	C. dubliniensis	Clinical isolate	ERG11	D288G, L300P, V437A	Multiple substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (32)	2002	12019078
5143(Patient1)	C. dubliniensis	Clinical isolate	ERG11	V125A, F126L, R398G, V437A	Multiple substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (32)	2002	12019078
CD36-C	C. dubliniensis	Laboratory strain	ERG3	H318N, P272L	Double substitution	Q8NJ57	386	AF-Q8NJ57-F1		Fluconazole (256), Itraconazole (64), Ketoconazole (2)	2003	12878500
CD36-F	C. dubliniensis	Laboratory strain	ERG3	Q160K	Single substitution	Q8NJ57	386	AF-Q8NJ57-F1		Fluconazole (256), Itraconazole (64), Ketoconazole (2)	2003	12878500
CD519-8A	C. dubliniensis	Laboratory strain	ERG11	V402G, I188V, R499K	Multiple substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (128), Itraconazole (32), Ketoconazole (4)	2003	12878500
CD570-A	C. dubliniensis	Laboratory strain	ERG11 ERG3	R210I, D225Y H269N	Double substitution Single substitution	B9WH07 Q8NJ57	528 386	AF-B9WH07-F1 AF-Q8NJ57-F1		Fluconazole (256), Itraconazole (64), Ketoconazole (2)	2003	12878500
CD570-B	C. dubliniensis	Laboratory strain	ERG11	R210I, D225Y	Double substitution	B9WH07	528	AF-B9WH07-F1		Fluconazole (256), Itraconazole (64), Ketoconazole (4)	2003	12878500
CD570-C	C. dubliniensis	Laboratory strain	ERG11 ERG3	R210I, D225Y Q327K	Double substitution Single substitution	B9WH07 Q8NJ57	528 386	AF-B9WH07-F1 AF-Q8NJ57-F1		Fluconazole (256), Itraconazole (64), Ketoconazole (2)	2003	12878500
CD570-D	C. dubliniensis	Laboratory strain	ERG11 ERG3	R210I, D225Y Q327K	Double substitution Single substitution	B9WH07 Q8NJ57	528 386	AF-B9WH07-F1 AF-Q8NJ57-F1		Fluconazole (256), Itraconazole (32), Ketoconazole (1)	2003	12878500
C369	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S	Multiple substitution	P10613	528	5V5Z		Itraconazole (1), Voriconazole (2), Posaconazole (0.25)	2004	14657086
C371	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S	Multiple substitution	P10613	528	5V5Z		Itraconazole (1), Voriconazole (4), Posaconazole (0.25), Fluconazole (>64)	2004	14657086
C372	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S	Multiple substitution	P10613	528	5V5Z		Itraconazole (1), Voriconazole (2), Posaconazole (0.25), Fluconazole (>64)	2004	14657086
C373	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S, P230L	Multiple substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (4), Posaconazole (2), Fluconazole (>64)	2004	14657086
C375	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S, P230L	Multiple substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Posaconazole (2)	2004	14657086
C376	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S, P230L	Multiple substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Posaconazole (2)	2004	14657086
C378	C. albicans	Clinical isolate	ERG11	K128T, Y132H, D278N, G464S	Multiple substitution	P10613	528	5V5Z		Itraconazole (1), Voriconazole (2), Posaconazole (0.25)	2004	14657086
isolate 1	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	14688046
isolate 10	C. albicans	Clinical isolate	ERG11	V509M	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2004	14688046
isolate 11	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	14688046
isolate 12	C. albicans	Clinical isolate	ERG11	R467K	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	14688046
isolate 5	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	14688046
isolate 7	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	14688046
C438	C. albicans	Clinical isolate	ERG11	Y257H, G464S	Double substitution	P10613	528	5V5Z		Fluconazole (128), Voriconazole (2)	2004	15155210
C439	C. albicans	Clinical isolate	ERG11	Y257H, G464S, G307S	Multiple substitution	P10613	528	5V5Z		Itraconazole (4), Fluconazole (>256), Voriconazole (16)	2004	15155210
C440	C. albicans	Clinical isolate	ERG11	Y257H, G464S, G307S, A61V	Multiple substitution	P10613	528	5V5Z		Posaconazole (4), Itraconazole (8), Fluconazole (>256), Voriconazole (>16)	2004	15155210
C444	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Fluconazole (256), Posaconazole (0.5), Itraconazole (0.5), Voriconazole (0.5)	2004	15155210
C477	C. albicans	Clinical isolate	ERG11	K128T, G464S, R467I	Multiple substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (16)	2004	15155210
C478	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2004	15155210
C480	C. albicans	Clinical isolate	ERG11	K128T, G464S, R467I	Multiple substitution	P10613	528	5V5Z		Fluconazole (128), Voriconazole (8)	2004	15155210
C489	C. albicans	Clinical isolate	ERG11	Y132H, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (128)	2004	15155210
C497	C. albicans	Clinical isolate	ERG11	K128T, V452A	Double substitution	P10613	528	5V5Z		Itraconazole (2), Fluconazole (64), Posaconazole (0.5), Voriconazole (0.5)	2004	15155210
C507	C. albicans	Clinical isolate	ERG11	Y132H, H283R, G464S	Multiple substitution	P10613	528	5V5Z		Itraconazole (2), Fluconazole (64), Voriconazole (8)	2004	15155210
C527	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2004	15155210
C528	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2004	15155210
C530	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (256)	2004	15155210
C534	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2004	15155210
C535	C. albicans	Clinical isolate	ERG11	Y132H, G448V	Double substitution	P10613	528	5V5Z		Itraconazole (2), Fluconazole (256), Voriconazole (8)	2004	15155210
C536	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2004	15155210
C539	C. albicans	Clinical isolate	ERG11	Y132H, G448V	Double substitution	P10613	528	5V5Z		Itraconazole (2), Fluconazole (128), Voriconazole (8)	2004	15155210
C546	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (128), Voriconazole (2)	2004	15155210
C572	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (128), Voriconazole (2)	2004	15155210
C577	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (128)	2004	15155210
C583	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (256)	2004	15155210
C587	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2004	15155210
C594	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Itraconazole (2), Fluconazole (128), Voriconazole (16), Posaconazole (0.5)	2004	15155210
C600	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Itraconazole (4), Fluconazole (>256), Voriconazole (16)	2004	15155210
148032	C. albicans	Clinical isolate	FCY1 FUR1	A31R, G107R C301Y	Double substitution Single substitution	P78594 Q59QT3	150 218	AF-P78594-F1 7RH8		5-Flucytosine (128)	2004	15155225
152050	C. albicans	Clinical isolate	FUR1	R101C	Single substitution	Q59QT3	218	7RH8		5-Flucytosine (128)	2004	15155225
157023	C. albicans	Clinical isolate	FCY1 FUR1	A31G, G107A R101C	Double substitution Single substitution	P78594 Q59QT3	150 218	AF-P78594-F1 7RH8		5-Flucytosine (128)	2004	15155225
175001	C. albicans	Clinical isolate	FCY1 FUR1	A31G, G107A R101C	Double substitution Single substitution	P78594 Q59QT3	150 218	AF-P78594-F1 7RH8		5-Flucytosine (128)	2004	15155225
178010	C. albicans	Clinical isolate	FCY1 FUR1	A31G, G107A R101C	Double substitution Single substitution	P78594 Q59QT3	150 218	AF-P78594-F1 7RH8		5-Flucytosine (128)	2004	15155225
14	C. albicans	Clinical isolate	ERG11	F380S	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	15380275
21	C. albicans	Clinical isolate	ERG11	H283D	Single substitution	P10613	528	5V5Z		Ketoconazole (1)	2004	15380275
23	C. albicans	Clinical isolate	ERG11	Y132F, F145L	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2004	15380275
33	C. albicans	Clinical isolate	ERG11	K143E, P503L	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2004	15380275
36	C. albicans	Clinical isolate	ERG11	Y79C, T199I	Double substitution	P10613	528	5V5Z		Fluconazole (>64), Ketoconazole (2)	2004	15380275
68	C. albicans	Clinical isolate	ERG11	I253V, V437I	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2004	15380275
8	C. albicans	Clinical isolate	ERG11	V130I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2004	15380275
C532	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (1), Voriconazole (8), Posaconazole (0.25)	2004	15388421
C600	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (8), Voriconazole (8), Posaconazole (1)	2004	15388421
TIMM3209	C. albicans	Clinical isolate	ERG11	Y132H, G448V	Double substitution	P10613	528	5V5Z		Fluconazole (>128), Itraconazole (1)	2004	15611610
CLY16038	C. krusei	Clinical isolate	FKS1	R1361G	Single substitution	Q4U2W2	1885	Model	Mismatch residue	Caspofungin (32) [RPMI 1640], Caspofungin (16) [AM3]	2005	16048935
CLY16996	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	O13428	1897	Model		Caspofungin (>8) [RPMI 1640], Caspofungin (2) [AM3]	2005	16048935
CLY16997	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	O13428	1897	Model		Caspofungin (>8) [RPMI 1640], Caspofungin (4) [AM3]	2005	16048935
CLY19230	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	O13428	1897	Model		Caspofungin (4) [RPMI 640], Caspofungin (2) [AM3]	2005	16048935
CLY19231	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	O13428	1897	Model		Caspofungin (4) [RPMI 1640], Caspofungin (2) [AM3]	2005	16048935
ISOLATE 29	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 34	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 35	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 36	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 37	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 38	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 41	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 42	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 43	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 44	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 45	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 46	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 47	C. albicans	Clinical isolate	ERG11	F126L, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 48	C. albicans	Clinical isolate	ERG11	T229A	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 49	C. albicans	Clinical isolate	ERG11	T229A	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 50	C. albicans	Clinical isolate	ERG11	V437I, D446N	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
ISOLATE 51	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (>64)	2005	16201925
21234	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	P14263	528	AF-P14263-F1		Clotrimazole (>250), Ketoconazole (1.5), Fluconazole (>256), Voriconazole (>32)	2005	16251302
Baseline	C. albicans	Clinical isolate	ERG11	F145L	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (32), Ravuconazole (4)	2006	16464893
week 36 no.1	C. albicans	Clinical isolate	ERG11 FKS1	F145L S645F, R1361H	Single substitution Double substitution	Q9P4W0 O13428	528 1897	AF-Q9P4W0-F1 Model		Amphotericin B (2), Itraconazole (2), Fluconazole (256), Voriconazole (2), Ravuconazole (>=16), Posaconazole (1), Micafungin (2), Caspofungin (2), Anidulafungin (1)	2006	16464893
week 36 no.2	C. albicans	Clinical isolate	ERG11 FKS1	F145L S645F, R1361H	Single substitution Double substitution	Q9P4W0 O13428	528 1897	AF-Q9P4W0-F1 Model		Itraconazole (>16), Fluconazole (>=512), Voriconazole (>=16), Ravuconazole (>=16), Posaconazole (2), Micafungin (2), Caspofungin (1)	2006	16464893
week 6	C. albicans	Clinical isolate	ERG11 FKS1	F145L S645F, R1361H	Single substitution Double substitution	Q9P4W0 O13428	528 1897	AF-Q9P4W0-F1 Model		Amphotericin B (2), Fluconazole (64), Voriconazole (1), Ravuconazole (4), Micafungin (2), Caspofungin (2), Anidulafungin (1)	2006	16464893
cg13928	C. glabrata	Clinical isolate	PDR1	F575L	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2006	16569856
cg4672	C. glabrata	Clinical isolate	PDR1	W297S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2006	16569856
Cg-ATCC2001-R	C. glabrata	Laboratory strain	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Caspofungin (2)	2006	16870797
AL-10R	C. albicans	Clinical isolate	CDR1	T950S	Single substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64)	2007	17126815
AL-1R	C. albicans	Clinical isolate	CDR1	T950S	Single substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Ketoconazole (2), Itraconazole (8)	2007	17126815
AL-2R	C. albicans	Clinical isolate	CDR1	T950S	Single substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Ketoconazole (1), Itraconazole (1)	2007	17126815
AL-3R	C. albicans	Clinical isolate	CDR1	I916V, T950S, A1416E	Multiple substitution	Q5ANA3	1501	AF-Q5ANA3-F1	Mismatch residue	Fluconazole (64)	2007	17126815
AL-4R	C. albicans	Clinical isolate	CDR1	T842S, I916V, T950S, F1399Y	Multiple substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Itraconazole (2)	2007	17126815
AL-5R	C. albicans	Clinical isolate	CDR1	T950S	Single substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Ketoconazole (2), Itraconazole (1)	2007	17126815
AL-6R	C. albicans	Clinical isolate	CDR1	I916V, T950S	Double substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Itraconazole (4)	2007	17126815
AL-7R	C. albicans	Clinical isolate	CDR1	T842S, I916V, T950S	Multiple substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64)	2007	17126815
AL-8R	C. albicans	Clinical isolate	CDR1	I916V, T950S, A1416E	Multiple substitution	Q5ANA3	1501	AF-Q5ANA3-F1	Mismatch residue	Fluconazole (64), Ketoconazole (4), Itraconazole (2)	2007	17126815
AL-9R	C. albicans	Clinical isolate	CDR1	I916V, T950S	Double substitution	Q5ANA3	1501	AF-Q5ANA3-F1		Fluconazole (64), Ketoconazole (2), Itraconazole (8)	2007	17126815
21229	C. glabrata	Clinical isolate	ERG6	C198F	Single substitution	Q6FRZ7	372	AF-Q6FRZ7-F1		Amphotericin B (1.3)	2007	17158937
Ck-100	C. krusei	Clinical isolate	FKS1	F655C	Single substitution	Q4U2W2	1885	Model		Caspofungin (8), Micafungin (4), Anidulafungin (4)	2007	17325225
isolate 3	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (0.5)	2007	17468115
isolate 4	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (1)	2007	17468115
DSY2322	C. albicans	Clinical isolate	ERG11 TAC1	S405F G980E	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (16)	2007	17693596
DSY2323	C. albicans	Clinical isolate	ERG11 TAC1	S405F G980E	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (32)	2007	17693596
DSY289 (C26)	C. albicans	Clinical isolate	ERG11 TAC1	S405F, Y132H A736V	Double substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (>128)	2007	17693596
DSY348 (C82)	C. albicans	Clinical isolate	ERG11 TAC1	S405F A736V	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (16)	2007	17693596
DSY3548 (isolate 16)	C. albicans	Clinical isolate	ERG11 TAC1	R467K A736V, L962-N969del	Single substitution Complex	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64)	2007	17693596
DSY3549 (isolate 17)	C. albicans	Clinical isolate	ERG11 TAC1	R467K A736V, L962-N969del	Single substitution Complex	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64)	2007	17693596
DSY3554 (D8-330)	C. albicans	Clinical isolate	TAC1	T225A	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (4)	2007	17693596
DSY3565 (D8-168)	C. albicans	Clinical isolate	TAC1	T225A	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (4)	2007	17693596
DSY732	C. albicans	Clinical isolate	TAC1	M677del	Deletion	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (16)	2007	17693596
DSY735	C. albicans	Clinical isolate	TAC1	M677del	Deletion	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (32)	2007	17693596
DSY296	C. albicans	Clinical isolate	TAC1	N977D	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		MIC90[Fluconazole (128)]	2007	17905926
ISOLATE 17	C. albicans	Clinical isolate	TAC1	A736C, L962-N969del	Complex	A0A1D8PN96	981	AF-A0A1D8PN96-F1	Structure not available	MIC80[Fluconazole (>64)	2007	17905926
ISOLATE 5674	C. albicans	Clinical isolate	TAC1	N972D	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		MIC50[Fluconazole (32)]	2007	17905926
592, 4263, 4266, GZ03, GZ09, GZ15, GZ16, GZ17, GZ18, GZ23, GZ29, GZ34, GZ51 and GZ58	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole	2008	18218640
BPY55	C. glabrata	Clinical isolate	PDR1	P822L	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (4), Ketoconazole (1), Voriconazole (2)	2008	18312269
Cgpgs1delta	C. glabrata	Laboratory strain	PGS1	I215F, E458D, N484S	Multiple substitution	Q6FXL9	506	AF-Q6FXL9-F1		Voriconazole (2), Posaconazole (32)	2008	18343926
06_3169	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Micafungin (2), Caspofungin (2)	2008	18378714
06_3170	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Micafungin (2), Caspofungin (2)	2008	18378714
960161	C. metapsilosis	Clinical isolate	FKS1	P660A	Single substitution	B0FTU4	887	AF-B0FTU4-F1	Mismatch residue	Anidulafungin (0.79), Caspofungin (1), Micafungin (1.59)	2008	18443110
981224	C. orthopsilosis	Clinical isolate	FKS1	P660A	Single substitution	B0FTU3	822	AF-B0FTU3-F1	Mismatch residue	Anidulafungin (1.26), Caspofungin (0.79), Micafungin (1.26)	2008	18443110
am-2006-0113	C. metapsilosis	Clinical isolate	FKS1	P660A	Single substitution	B0FTU4	887	AF-B0FTU4-F1	Mismatch residue	Anidulafungin (0.63), Caspofungin (0.79), Micafungin (1.59)	2008	18443110
ATCC 22019	C. parapsilosis	Laboratory strain	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Anidulafungin (1.10), Caspofungin (1.40), Micafungin (1.60)	2008	18443110
H10	C. orthopsilosis	Clinical isolate	FKS1	P660A	Single substitution	B0FTU3	822	AF-B0FTU3-F1	Mismatch residue	Anidulafungin (0.79), Caspofungin (1), Micafungin (0.63)	2008	18443110
H4	C. parapsilosis	Clinical isolate	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Anidulafungin (2.24), Caspofungin (2.24), Micafungin (1.12)	2008	18443110
H5	C. parapsilosis	Clinical isolate	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Anidulafungin (1.59), Caspofungin (2.24), Micafungin (1.26)	2008	18443110
m122	C. albicans	Clinical isolate	FKS1	P649H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.15), Caspofungin (4), Micafungin (0.25)	2008	18443110
T51916	C. glabrata	Clinical isolate	FKS2	P633T	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (1.59), Caspofungin (2), Micafungin (0.40)	2008	18443110
ISOLATE S2	C. albicans	Clinical isolate	ERG11 UPC2	G307S, G448E G648D	Double substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (>64)	2008	18487346
1587	C. albicans	Clinical isolate	MRR1	N803D	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
2271	C. albicans	Clinical isolate	MRR1	Q350L	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
5052	C. albicans	Clinical isolate	MRR1	P683H	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
6692	C. albicans	Clinical isolate	MRR1	T360I, K335N	Double substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
B4	C. albicans	Clinical isolate	MRR1	G878E	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
CAPR510	C. albicans	Laboratory strain	MRR1	T381I	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
CAPR513	C. albicans	Laboratory strain	MRR1	A880E	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
CAPR514	C. albicans	Laboratory strain	MRR1	W893R	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
CAPR515	C. albicans	Laboratory strain	MRR1	R873T	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
CAPR517	C. albicans	Laboratory strain	MRR1	L998F	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
DSY2286	C. albicans	Clinical isolate	MRR1	T896I	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
DSY292	C. albicans	Clinical isolate	MRR1	P683H	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
F5	C. albicans	Clinical isolate	MRR1	P683S	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
G5	C. albicans	Clinical isolate	MRR1	G997V	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2008	18577180
ISOLATE 1	C. krusei	Clinical isolate	FKS1	L658W, L701M	Double substitution	Q4U2W2	1885	Model		Caspofungin (8) [RPMI], Caspofungin (4) [AM3]	2008	18591282
ISOLATE 19	C. albicans	Clinical isolate	FKS1	P649H, W1358R	Double substitution	O13428	1897	Model		Caspofungin (1) [RPMI], Caspofungin (0.5) [AM3]	2008	18591282
ISOLATE 2	C. tropicalis	Clinical isolate	FKS1	L644W	Single substitution	C5M4K6	1640	Model	Mismatch residue	Caspofungin (2) [RPMI], Caspofungin (1) [AM3]	2008	18591282
ISOLATE 20	C. albicans	Clinical isolate	FKS1	F641S, S645P	Double substitution	O13428	1897	Model		Caspofungin (2) [RPMI], Caspofungin (2) [AM3]	2008	18591282
ISOLATE 21	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	O13428	1897	Model		Caspofungin (2) [RPMI], Caspofungin (1) [AM3]	2008	18591282
ISOLATE 22	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	O13428	1897	Model		Caspofungin (2) [RPMI], Caspofungin (1) [AM3]	2008	18591282
ISOLATE 23	C. albicans	Clinical isolate	FKS1	W1358R	Single substitution	O13428	1897	Model		Caspofungin (2) [RPMI], Caspofungin (0.5) [AM3]	2008	18591282
ISOLATE 24	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	O13428	1897	Model		Caspofungin (4) [RPMI], Caspofungin (16) [AM3]	2008	18591282
CD51II-A	C. dubliniensis	Laboratory strain	MRR1	D987-I998del	Deletion	B9WEH2	1100	AF-B9WEH2-F1	Structure not available	Fluconazole	2008	18809934
CD51II-B	C. dubliniensis	Laboratory strain	MRR1	T985del	Deletion	B9WEH2	1100	AF-B9WEH2-F1	Structure not available	Fluconazole	2008	18809934
CD57A	C. dubliniensis	Laboratory strain	MRR1	S595Y	Single substitution	B9WEH2	1100	AF-B9WEH2-F1		Fluconazole	2008	18809934
CD57B	C. dubliniensis	Laboratory strain	MRR1	T374I	Single substitution	B9WEH2	1100	AF-B9WEH2-F1		Fluconazole	2008	18809934
CM2	C. dubliniensis	Clinical isolate	MRR1	C866Y	Single substitution	B9WEH2	1100	AF-B9WEH2-F1		Fluconazole	2008	18809934
119	C. albicans	Clinical isolate	FKS1	F641L	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.16), Caspofungin (2.0), Micafungin (0.33)	2009	18955538
121	C. albicans	Clinical isolate	FKS1	R1361H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.25), Caspofungin (2.0), Micafungin (0.25)	2009	18955538
122	C. albicans	Clinical isolate	FKS1	P649H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.67), Caspofungin (4.0), Micafungin (0.83)	2009	18955538
149	C. albicans	Clinical isolate	FKS1	D648Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.83), Caspofungin (2.67), Micafungin (0.83)	2009	18955538
177	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.83), Caspofungin (4.0), Micafungin (1.0)	2009	18955538
194	C. albicans	Clinical isolate	FKS1	S645F, R1361H	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (4), Caspofungin (4), Micafungin (2.67)	2009	18955538
205	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1.33), Caspofungin (8.0), Micafungin (4)	2009	18955538
2762	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Caspofungin (3.33), Micafungin (1)	2009	18955538
5415	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (2), Caspofungin (8.0), Micafungin (4)	2009	18955538
85	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (2), Caspofungin (4), Micafungin (2.67)	2009	18955538
89	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (2), Caspofungin (8.0), Micafungin (4)	2009	18955538
90	C. albicans	Clinical isolate	FKS1	R1361H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.25), Caspofungin (1.0), Micafungin (0.50)	2009	18955538
A15	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (4.0), Micafungin (0.5)	2009	18955538
A15-10	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (4), Caspofungin (8.0), Micafungin (4)	2009	18955538
y0109R	C. albicans	Laboratory strain	TAC1	L47K, N977K	Double substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1	Mismatch residue	Fluconazole	2008	19089303
y0109R(ATCC76615)	C. albicans	Laboratory strain	ERG3	D19E	Single substitution	Q59VG6	386	AF-Q59VG6-F1		Fluconazole	2008	19089303
C. albicans R	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		ETEST[Caspofungin (>32), Anidulafungin (0.5)], EUCAST[Caspofungin (2), Anidulafungin (0.125)], CLSI[Caspofungin (1), Anidulafungin (0.5)]	2009	19104024
DSY2234	C. glabrata	Clinical isolate	PDR1	T588A	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (1), Ketoconazole (1)	2009	19148266
DSY2254	C. glabrata	Clinical isolate	PDR1	D1082G	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY2257	C. glabrata	Clinical isolate	PDR1	N691D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (1), Ketoconazole (1)	2009	19148266
DSY2268	C. glabrata	Clinical isolate	PDR1	S316I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (1), Ketoconazole (1)	2009	19148266
DSY2271	C. glabrata	Clinical isolate	PDR1	D261G	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY2273	C. glabrata	Clinical isolate	PDR1	R293I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (2), Ketoconazole (1)	2009	19148266
DSY2277	C. glabrata	Clinical isolate	PDR1	R592S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (2), Ketoconazole (1)	2009	19148266
DSY2279	C. glabrata	Clinical isolate	PDR1	G583S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32)	2009	19148266
DSY2315	C. glabrata	Clinical isolate	PDR1	R376G	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32)	2009	19148266
DSY489	C. glabrata	Clinical isolate	PDR1	L328F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY530	C. glabrata	Clinical isolate	PDR1	E1083Q	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY565	C. glabrata	Clinical isolate	PDR1	I280F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Mismatch residue	Fluconazole (128), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY704	C. glabrata	Clinical isolate	PDR1	T607S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (1), Ketoconazole (1)	2009	19148266
DSY727	C. glabrata	Clinical isolate	PDR1	D876Y	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY739	C. glabrata	Clinical isolate	PDR1	R376W	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY754	C. glabrata	Clinical isolate	PDR1	Y584C	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32), Itraconazole (1), Ketoconazole (1)	2009	19148266
DSY756	C. glabrata	Clinical isolate	PDR1	S343F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (2), Ketoconazole (2)	2009	19148266
DSY774	C. glabrata	Clinical isolate	PDR1	R376G	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (1)	2009	19148266
isolate 1	C. glabrata	Clinical isolate	ERG11 PDR1	E502V H576Y	Single substitution Single substitution	P50859 Q6FXU7	533 1107	5JLC AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (8), Voriconazole (32)	2009	19196495
isolate 21	C. glabrata	Clinical isolate	ERG11 PDR1	E502V H576Y	Single substitution Single substitution	P50859 Q6FXU7	533 1107	5JLC AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (>8), Voriconazole (>32)	2009	19196495
isolate 22	C. glabrata	Clinical isolate	ERG11 PDR1	E502V H576Y	Single substitution Single substitution	P50859 Q6FXU7	533 1107	5JLC AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (>8), Voriconazole (>32)	2009	19196495
isolate 27	C. glabrata	Clinical isolate	ERG11 PDR1	E502V H576Y	Single substitution Single substitution	P50859 Q6FXU7	533 1107	5JLC AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (>8), Voriconazole (>32)	2009	19196495
isolate 3	C. glabrata	Clinical isolate	PDR1	L347F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (2), Voriconazole (>32)	2009	19196495
isolate 7	C. glabrata	Clinical isolate	ERG11 PDR1	E502V H576Y	Single substitution Single substitution	P50859 Q6FXU7	533 1107	5JLC AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (4), Voriconazole (32)	2009	19196495
21900	C. glabrata	Clinical isolate	FKS1	D632G	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (4), Micafungin (0.5)	2009	19546367
234	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4), Micafungin (1)	2009	19546367
31498	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (4)	2009	19546367
3169	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2.52), Micafungin (2.52)	2009	19546367
3830	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (16), Micafungin (1)	2009	19546367
41026	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (4)	2009	19546367
41400	C. glabrata	Clinical isolate	FKS2	D666G	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (4), Micafungin (0.12)	2009	19546367
42031	C. glabrata	Clinical isolate	FKS2	D666E	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4), Micafungin (0.25)	2009	19546367
42971	C. glabrata	Clinical isolate	FKS1 FKS2	D632Y R1377stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (8), Micafungin (1)	2009	19546367
42997	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (8), Micafungin (0.5)	2009	19546367
51916	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1.59), Caspofungin (2), Micafungin (0.4)	2009	19546367
5416	C. glabrata	Clinical isolate	FKS2	W1375L	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (4), Micafungin (0.25)	2009	19546367
5847	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (8), Micafungin (2)	2009	19546367
10	C. albicans	Clinical isolate	ERG11	S405F, Y132H	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
11	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
12-A	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
14	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (>16)	2009	19682357
15	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (16)	2009	19682357
16-B	C. albicans	Clinical isolate	ERG11	G307S, G448E, K128T	Multiple substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (2)	2009	19682357
16-C	C. albicans	Clinical isolate	ERG11	G307S, G448E, G464S, K128T	Multiple substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (16)	2009	19682357
17	C. albicans	Clinical isolate	ERG11	D278E	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (64)	2009	19682357
18	C. albicans	Clinical isolate	ERG11	K128T, R467K	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (128)	2009	19682357
19	C. albicans	Clinical isolate	ERG11	K128T, K143R	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
4	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
5	C. albicans	Clinical isolate	ERG11	G307S	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
7	C. albicans	Clinical isolate	ERG11	G464S, K143R	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (>16)	2009	19682357
8-A	C. albicans	Clinical isolate	ERG11	F449S	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256)	2009	19682357
8-B	C. albicans	Clinical isolate	ERG11	F449S	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256),	2009	19682357
9	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (>16)	2009	19682357
C438	C. albicans	Clinical isolate	ERG11	Y257H, G464S	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (128)	2009	19682357
C440	C. albicans	Clinical isolate	ERG11	A61V, Y257H, G307S, G464S	Multiple substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (>256), Voriconazole (>16)	2009	19682357
C480	C. albicans	Clinical isolate	ERG11	G464S, K128T, R467I	Multiple substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (128), Voriconazole (8)	2009	19682357
C507	C. albicans	Clinical isolate	ERG11	G464S, H283R, Y132H	Multiple substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (64), Voriconazole (8)	2009	19682357
C527	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (256), Voriconazole (4)	2009	19682357
C577	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (128)	2009	19682357
C594	C. albicans	Clinical isolate	ERG11	S405F, Y132H	Double substitution	Q9UVT4	528	AF-Q9UVT4-F1		Fluconazole (128), Voriconazole (16)	2009	19682357
348	C. albicans	Clinical isolate	ERG11	D153E	Single substitution	P10613	528	5V5Z		Fluconazole (>64), Itraconazole (2), Ketoconazole (2), Micafungin (>64)	2011	19732347
B	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Itraconazole (1), Ketoconazole (2), Micafungin (>64)	2011	19732347
H1	C. albicans	Clinical isolate	ERG11	K143R, S412T, R469K	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Itraconazole (4), Ketoconazole (4), Micafungin (>64), Clotrimazole (1)	2011	19732347
H2	C. albicans	Clinical isolate	ERG11	K143R, S412T, R469K	Multiple substitution	P10613	528	5V5Z		Itraconazole (2), Ketoconazole (2), Micafungin (64)	2011	19732347
H3	C. albicans	Clinical isolate	ERG11	G464S, G465S	Double substitution	P10613	528	5V5Z		Itraconazole (2), Ketoconazole (2), Micafungin (64)	2011	19732347
S2 (HIV patients)	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>64)	2009	19750515
isolate 2(03.01.2002)	C. glabrata	Clinical isolate	FUR1	G190D	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (>32)	2010	20038613
isolate 3(07.01.2002)	C. glabrata	Clinical isolate	FUR1	G190D	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (>32)	2010	20038613
isolate 4(14.03.2002)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Fluconazole (>256), Voriconazole (12), Caspofungin (>32)	2010	20038613
isolate 5(16.03.2002)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Fluconazole (>256), Voriconazole (16), Caspofungin (>32)	2010	20038613
177	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.83), Caspofungin (4), Micafungin (1)	2010	20145084
205	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1.33), Caspofungin (8), Micafungin (4)	2010	20145084
CG-C2	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (8), Micafungin (2)	2010	20145084
CG-C3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (8), Caspofungin (>16), Micafungin (>16)	2010	20145084
CT-C1	C. tropicalis	Clinical isolate	FKS1	F76S	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (4), Micafungin (1)	2010	20145084
2897	C. albicans	Clinical isolate	ERG11	G206D	Single substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (>16), Itraconazole (>16)	2010	20367978
2972	C. albicans	Clinical isolate	ERG11	N349S, G227D	Double substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (0.06), Itraconazole (>16)	2010	20367978
2989	C. albicans	Clinical isolate	ERG11	D153E, F72S, F416S	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (>16), Itraconazole (>16)	2010	20367978
2990	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (0.06), Itraconazole (0.5)	2010	20367978
3997	C. albicans	Clinical isolate	ERG11	D153E, F145I	Double substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (>16), Itraconazole (0.5)	2010	20367978
416	C. albicans	Clinical isolate	ERG11	R467K	Single substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (0.125), Itraconazole (0.5)	2010	20367978
716	C. albicans	Clinical isolate	ERG11	Y132H, G448E, G464S, T482A	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (>16), Itraconazole (2)	2010	20367978
717	C. albicans	Clinical isolate	ERG11	Y132H, G448E, F103L, F198L, F422L	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Voriconazole (2), Itraconazole (1)	2010	20367978
4690	C. glabrata	Clinical isolate	FKS2	L644W	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Caspofungin (0.25), Anidulafungin (0.12), Micafungin (0.06)	2010	20368396
4700	C. albicans	Clinical isolate	FKS1	F641Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2010	20368396
4707	C. glabrata	Clinical isolate	FKS2	S645P	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Caspofungin (8), Anidulafungin (4), Micafungin (2)	2010	20368396
4708	C. glabrata	Clinical isolate	FKS1	S645P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (≥8), Anidulafungin (4), Micafungin (4)	2010	20368396
4720	C. glabrata	Clinical isolate	FKS2	S645P	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Caspofungin (≥8), Anidulafungin (4), Micafungin (4)	2010	20368396
4748	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (4), Anidulafungin (1), Micafungin (0.5)	2010	20368396
4780	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (4), Anidulafungin (1), Micafungin (0.5)	2010	20368396
Patient1	C. krusei	Clinical isolate	FKS1	H675Q	Single substitution	Q4U2W2	1885	Model		Anidulafungin (0.25), Caspofungin (1), Micafungin (0.25)	2010	20421445
Patient11	C. tropicalis	Clinical isolate	FKS1 FKS1	S80P S80P	Single substitution Single substitution	B6S6L8 B6S6L8	1904 1904	Model Model		Anidulafungin (4), Caspofungin (8), Micafungin (2) Anidulafungin (2), Caspofungin (4), Micafungin (2)	2010	20421445
Patient3	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (8), Caspofungin (>16), Micafungin (8)	2010	20421445
Patient5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2010	20421445
Patient7	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (4), Micafungin (4)	2010	20421445
Patient8	C. glabrata	Clinical isolate	FKS2 FKS2	S663P S663P	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Anidulafungin (8), Caspofungin (>16), Micafungin (8) Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2010	20421445
GZ03	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ09	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ15	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ16	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ17	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ18	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ23	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ29	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ34	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ51	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
GZ58	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
J4263	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
J4266	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
J592	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2010	20515567
CA108	C. albicans	Clinical isolate	ERG11 ERG5	A114S 116RDLARKILSS125insertion	Single substitution Insertion	P10613 O94016	528 517	5V5Z AF-O94016-F1		Fluconazole (64), Voriconazole (8), Itraconazole (2), Ketoconazole (1), Clotrimazole (2), Amphotericin B (2)	2010	20547793
Cg12R	C. glabrata	Clinical isolate	PDR1	G348A	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg14R	C. glabrata	Clinical isolate	PDR1	N764I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg16R	C. glabrata	Clinical isolate	PDR1	R772I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg18R	C. glabrata	Clinical isolate	PDR1	L344S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg22R	C. glabrata	Clinical isolate	PDR1	L280F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg2R	C. glabrata	Clinical isolate	PDR1	F575L	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg4R	C. glabrata	Clinical isolate	PDR1	S391L	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg6R	C. glabrata	Clinical isolate	PDR1	G943S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
Cg8R	C. glabrata	Clinical isolate	PDR1	W297S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2010	20547810
CA1008	C. albicans	Clinical isolate	ERG3	K97E, L193P, V237A, A351V, A353T	Multiple substitution	O93875	386	AF-O93875-F1	Mismatch residue	Fluconazole (>256), Voriconazole (>16), Itraconazole (>16), Ketoconazole (>16), Clotrimazole (1), Fluconazole (>256), Voriconazole (>16)	2010	20733039
CA12	C. albicans	Clinical isolate	ERG3	W332R	Single substitution	O93875	386	AF-O93875-F1		Fluconazole (>256), Voriconazole (>16), Itraconazole (>16), Ketoconazole (>16), Clotrimazole (1), Fluconazole (>256), Voriconazole (>16)	2010	20733039
CA488	C. albicans	Clinical isolate	ERG11 ERG3	D225G, E391G H243N, T330A, A351V	Double substitution Multiple substitution	P10613 O93875	528 386	5V5Z AF-O93875-F1		Fluconazole (>256), Voriconazole (>16), Itraconazole (>16), Ketoconazole (8), Clotrimazole (1)	2010	20733039
CA490	C. albicans	Clinical isolate	ERG11 ERG3	F72S, T229A, N440S, R523G D147G, T330A, A351V	Multiple substitution Multiple substitution	P10613 O93875	528 386	5V5Z AF-O93875-F1		Fluconazole (>256), Voriconazole (>16), Itraconazole (>16), Ketoconazole (8), Clotrimazole (1)	2010	20733039
20251.021	C. glabrata	Clinical isolate	FCY1	T84L	Single substitution	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)]	2010	20823283
20408.055	C. glabrata	Clinical isolate	FUR1	G210D	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (≥32), 5-Flucytosine (≥4)]	2010	20823283
66-FC1	C. glabrata	Laboratory strain	FUR1	I83K	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (≥32), 5-Flucytosine (≥4)	2010	20823283
66-FC2	C. glabrata	Laboratory strain	FUR1	G73-V81del	Deletion	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (≥32), 5-Flucytosine (≥4)	2010	20823283
66-FC3	C. glabrata	Laboratory strain	FUR1	G71V	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (≥32), 5-Flucytosine (≥4)	2010	20823283
66-FC4	C. glabrata	Laboratory strain	FCY1	A15D	Single substitution	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)	2010	20823283
66-FC5	C. glabrata	Laboratory strain	FCY1	A15D	Single substitution	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)	2010	20823283
66-FC6	C. glabrata	Laboratory strain	FCY1	G11D	Single substitution	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)	2010	20823283
66u-FC3	C. glabrata	Laboratory strain	FCY1	H59D	Single substitution	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)	2010	20823283
66u-FC6	C. glabrata	Laboratory strain	FCY1	T92delstop	Stop	Q6FWB1	155	AF-Q6FWB1-F1	Structure not available	5-Flucytosine (≥32)	2010	20823283
BG-FC4	C. glabrata	Laboratory strain	FCY1	E17stop	Stop	Q6FWB1	155	AF-Q6FWB1-F1		5-Flucytosine (≥32)]	2010	20823283
TE34-78	C. glabrata	Clinical isolate	FUR1	L136R	Single substitution	Q6FRF1	216	AF-Q6FRF1-F1		5-Flucytosine (≥32), 5-Flucytosine (≥4)]	2010	20823283
CAS08-0016	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2010	20837754
CAS08-0037	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2010	20837754
CAS08-0094	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2010	20837754
CAS08-0209	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8), Micafungin (4)	2010	20837754
CAS08-0293	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (>16), Micafungin (4)	2010	20837754
CAS08-0311	C. glabrata	Clinical isolate	FKS2	P667H	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2010	20837754
CAS08-0425	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (4)	2010	20837754
CAS08-0725	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25)	2010	20837754
CAS09-0901	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2010	20837754
CAS09-1083	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.125)	2010	20837754
CAS09-1204	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (1), Micafungin (2)	2010	20837754
CAS09-1225	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2010	20837754
CAS09-1437	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.5)	2010	20837754
CAS09-1616	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (2)	2010	20837754
CAS09-1648	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.125), Micafungin (0.25)	2010	20837754
CAS09-1786	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2010	20837754
DST1151	C. albicans	Clinical isolate	TAC1	N740S	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (48), Itraconazole (1)	2010	20876623
DST1152	C. albicans	Clinical isolate	ERG11 TAC1	Y132F F973S, S290C	Single substitution Double substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (24), Itraconazole (1)	2010	20876623
DST1154	C. albicans	Clinical isolate	TAC1	H741Y	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (48), Itraconazole (0.75)	2010	20876623
DST1156	C. albicans	Clinical isolate	ERG11 TAC1	Y132F F973S, S290C	Single substitution Double substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64), Itraconazole (0.5)	2010	20876623
DST1157	C. albicans	Clinical isolate	TAC1	N740S	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (48), Itraconazole (1.5)	2010	20876623
DST1158	C. albicans	Clinical isolate	ERG11 TAC1	H283R S108N	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (48)	2010	20876623
DST1318	C. albicans	Clinical isolate	ERG11 TAC1	D153E N972S	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (32), Itraconazole (1.5)	2010	20876623
DST1489	C. albicans	Clinical isolate	ERG11 TAC1	D153E N972S	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (48), Itraconazole (12)	2010	20876623
DST1490	C. albicans	Clinical isolate	TAC1 TAC1	R673Q R673Q	Single substitution Single substitution	A0A1D8PN96 A0A1D8PN96	981 981	AF-A0A1D8PN96-F1 AF-A0A1D8PN96-F1		Fluconazole (48), Itraconazole (2) Fluconazole (128), Itraconazole (2)	2010	20876623
DST1492	C. albicans	Clinical isolate	TAC1	H741Y	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (24), Itraconazole (1.5)	2010	20876623
DST1493	C. albicans	Clinical isolate	TAC1	N977D, P276L	Double substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (6), Itraconazole (1.5)	2010	20876623
DST1494	C. albicans	Clinical isolate	TAC1	E461K	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (128), Itraconazole (2)	2010	20876623
DST1495	C. albicans	Clinical isolate	ERG11 TAC1	S405F E461K	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (32), Itraconazole (1.5)	2010	20876623
DST203	C. albicans	Clinical isolate	ERG11 TAC1	G464S N740D	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (96), Itraconazole (2)	2010	20876623
DST360	C. albicans	Clinical isolate	ERG11 TAC1	H283R A736T	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64), Itraconazole (12)	2010	20876623
5674	C. albicans	Clinical isolate	TAC1	N972D	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole	2009	21136999
6692	C. albicans	Clinical isolate	MRR1	T360I, K335N	Double substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2009	21136999
C56	C. albicans	Clinical isolate	TAC1	N977D	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole	2009	21136999
F5	C. albicans	Clinical isolate	MRR1	P683S	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2009	21136999
G5	C. albicans	Clinical isolate	MRR1	G997V	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole	2009	21136999
Gu5	C. albicans	Clinical isolate	TAC1	L979E	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole	2009	21136999
CT	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5MF18	1280	AF-C5MF18-F1	Mismatch residue	Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2011	21146713
Germany	C. albicans	Clinical isolate	FKS1	F641I	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2011	21146713
West Roxbury, MA	C. glabrata	Clinical isolate	FKS1	L641I	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (1)	2011	21146713
30-2	C. glabrata	Clinical isolate	FKS2	S633P	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Caspofungin (32), Anidulafungin (4), Micafungin (8)	2011	21149621
44944	C. glabrata	Clinical isolate	FKS2	P659del	Deletion	Q6FMZ3	1897	Model	Mismatch residue	Caspofungin (>32), Anidulafungin (4), Micafungin (4)	2011	21149621
ISOLATE 6955	C. glabrata	Clinical isolate	PDR1	K274N	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (16)	2011	21193550
SM3	C. glabrata	Clinical isolate	PDR1	L946S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2011	21193550
20S	C. albicans	Laboratory strain	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		CLSI[Micafungin (1)], EUCAST[Micafungin (2)]	2011	21502627
22S	C. albicans	Laboratory strain	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		CLSI[Micafungin (2)], EUCAST[Micafungin (2)]	2011	21502627
36S	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		CLSI[Micafungin (1)], EUCAST[Micafungin (2)]	2011	21502627
A15	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		CLSI[Micafungin (0.5)], EUCAST[Micafungin (1)]	2011	21502627
43001	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4)	2011	21502632
53264	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4)	2011	21502632
BC014R(FLC)	C. parapsilosis	Clinical isolate	MRR1	G583R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (128), Voriconazole (4)	2011	21518843
BC014R(VRC)	C. parapsilosis	Clinical isolate	MRR1	K873N	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (128), Voriconazole (4)	2011	21518843
Ct-R	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (2), Caspofungin (8)	2011	21543574
CAAL37	C. albicans	Clinical isolate	ERG11	G464S, V456I	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2011	21698128
CAAL61	C. albicans	Clinical isolate	ERG11	G307S, Y447H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2011	21698128
A152	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (4), Micafungin (0.5)	2011	21791665
CLY16996	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (2), Caspofungin (4), Micafungin (2.67)	2011	21791665
CLY16997	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2011	21791665
CLY19230	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2011	21791665
Cg30	C. glabrata	Laboratory strain	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (2.0), Micafungin (0.5), Amphotericin B (1)	2012	22203604
Cg51	C. glabrata	Clinical isolate	FKS2	D666G	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25), Amphotericin B (1)	2012	22203604
VSY2	C. albicans	Clinical isolate	ERG3	A351V	Single substitution	Q59VG6	386	AF-Q59VG6-F1		Fluconazole (>128), Itraconazole (>16), Voriconazole (>16), Posaconazole (>16), Amphotericin B (2)	2012	22252807
05BL1-38	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (1), Anidulafungin (0.125)	2012	22257484
06BL1-33	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8), Micafungin (8), Anidulafungin (2)	2012	22257484
06BL1-34	C. krusei	Clinical isolate	FKS1	L648W	Single substitution	Q4U2W2	1885	Model	Mismatch residue	Caspofungin (8), Micafungin (4), Anidulafungin (2)	2012	22257484
06BL2-127	C. albicans	Clinical isolate	FKS1	F641S, S645P	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (0.5), Anidulafungin (0.125)	2012	22257484
07BL2-157	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Caspofungin (1), Micafungin (0.5), Anidulafungin (0.5)	2012	22257484
08BL1-94	C. albicans	Clinical isolate	FKS1	R1361G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (1), Anidulafungin (0.5)	2012	22257484
08BL2-142	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (4), Micafungin (2), Anidulafungin (2)	2012	22257484
08BL2-143	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (2), Anidulafungin (0.5)	2012	22257484
09BL1-43	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (1), Anidulafungin (0.25)	2012	22257484
09BL1-55	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (4), Micafungin (4), Anidulafungin (0.5)	2012	22257484
09BL1-77	C. albicans	Clinical isolate	FKS1	R647G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.5), Micafungin (0.25), Anidulafungin (0.03)	2012	22257484
10BL1-19	C. glabrata	Clinical isolate	FKS2	F659S, L664V	Double substitution	Q6FMZ3	1897	Model		Caspofungin (4), Micafungin (0.5), Anidulafungin (1)	2012	22257484
10BL1-50	C. krusei	Clinical isolate	FKS1	F645L	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (2), Anidulafungin (1)	2012	22257484
10BL1-67	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Caspofungin (4), Micafungin (1), Anidulafungin (1)	2012	22257484
ODL13-1254	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (1), Micafungin (0.5)	2012	22257484
ODL19-1894	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Micafungin (20, Anidulafungin (0.25)	2012	22257484
ODL21-2028	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Caspofungin (1), Micafungin (0.25), Anidulafungin (0.25)	2012	22257484
ODL22-2183	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (2), Micafungin (0.25), Anidulafungin (1)	2012	22257484
ODL23-2221	C. glabrata	Clinical isolate	FKS1 FKS2	F625I P667T	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (4), Micafungin (2), Anidulafungin (0.25)	2012	22257484
ODL7-647	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Caspofungin (8), Micafungin (1), Anidulafungin (0.125)	2012	22257484
10956A	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.12)	2012	22278842
127F	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (16), Micafungin (2)	2012	22278842
30011F	C. glabrata	Clinical isolate	FKS1	D648E	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (0.25), Caspofungin (0.5), Micafungin (0.03)	2012	22278842
748F	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.12)	2012	22278842
CAS08-0016	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2012	22278842
CAS08-0094	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2012	22278842
CAS08-0425	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (4)	2012	22278842
CAS09-0869	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2012	22278842
CAS09-1083	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.12)	2012	22278842
CAS09-1225	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2012	22278842
CAS09-1437	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.5)	2012	22278842
CAS09-1680	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.5), Micafungin (1)	2012	22278842
CAS09-1786	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2012	22278842
CAS11-2978	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.5), Micafungin (0.12)	2012	22278842
CAS11-3112	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.12)	2012	22278842
CAS11-3129	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2012	22278842
CL7369	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.12), Caspofungin (1), Micafungin (0.06)	2012	22391532
CL7370	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (1), Micafungin (0.12)	2012	22391532
4872	C. glabrata	Clinical isolate	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2), Caspofungin (32)	2012	22514266
delFKS1 V1	C. glabrata	Laboratory strain	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Micafungin (4)	2012	22514266
delFKS1 V2	C. glabrata	Laboratory strain	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4)	2012	22514266
delFKS2 V1	C. glabrata	Laboratory strain	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (2)	2012	22514266
delFKS2 V2	C. glabrata	Laboratory strain	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Micafungin (4)	2012	22514266
G17 V	C. glabrata	Laboratory strain	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2012	22514266
H10	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (0.125), Caspofungin (2)	2012	22514266
H10 V1	C. glabrata	Laboratory strain	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2012	22514266
H10 V2	C. glabrata	Laboratory strain	FKS1 FKS2	S629P R1378G	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (4)	2012	22514266
H10 V3	C. glabrata	Laboratory strain	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2012	22514266
H10 V4	C. glabrata	Laboratory strain	FKS1 FKS1	A352D S629P	Single substitution Single substitution	Q6FTN8 Q6FTN8	1863 1863	Model Model		Micafungin (2)	2012	22514266
H10 V5	C. glabrata	Laboratory strain	FKS1 FKS2	S629P G1534S	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2012	22514266
H10 V6	C. glabrata	Laboratory strain	FKS1 FKS2	S629P T458K	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (4)	2012	22514266
H10 V7	C. glabrata	Laboratory strain	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2012	22514266
H10T13	C. glabrata	Clinical isolate	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2), Caspofungin (32)	2012	22514266
NAU3 V	C. glabrata	Laboratory strain	FKS1 FKS2	S629P 1547stop	Single substitution Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (0.625)	2012	22514266
CG156	C. glabrata	Clinical isolate	ERG11	G315D	Single substitution	P50859	533	5JLC		Fluconazole (>256), Voriconazole (>256), Amphotericin B (32)	2012	22615281
patient isolate	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (>4), Anidulafungin (0.5), Micafungin (2)	2012	22653922
CAAL2	C. albicans	Clinical isolate	ERG11 ERG3	D153E L193R, V351A	Single substitution Double substitution	P10613 O93875	528 386	5V5Z AF-O93875-F1		Fluconazole (>64), Voriconazole (>8) [CLSI] Amphotericin B (0.75) [Etest]	2012	22678731
CAAL76	C. albicans	Clinical isolate	ERG11 ERG3	K128T L122-I125del	Single substitution Deletion	P10613 O93875	528 386	5V5Z AF-O93875-F1		Fluconazole (>64), Voriconazole (>8) [CLSI] Amphotericin B (1) [Etest]	2012	22678731
isolate 13	C. albicans	Clinical isolate	UPC2	A643T	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (16)	2012	22923048
isolate 15	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (16)	2012	22923048
isolate 18	C. albicans	Clinical isolate	UPC2	G304R	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (32)	2012	22923048
isolate 19	C. albicans	Clinical isolate	UPC2	G304R	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (32)	2012	22923048
isolate 21	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (32)	2012	22923048
isolate 25	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2012	22923048
isolate 27	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2012	22923048
isolate 28	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2012	22923048
isolate 30	C. albicans	Clinical isolate	UPC2	A643V	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2012	22923048
isolate 33	C. albicans	Clinical isolate	UPC2	Y642F	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (36)	2012	22923048
isolate 34	C. albicans	Clinical isolate	UPC2	Y642F	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (37)	2012	22923048
isolate 35	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 38	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2012	22923048
isolate 45	C. albicans	Clinical isolate	UPC2	A646V	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (128)	2012	22923048
isolate 47	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (128)	2012	22923048
isolate 52	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (256)	2012	22923048
isolate 55	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 56	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 57	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 58	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 59	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 65	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 67	C. albicans	Clinical isolate	UPC2 UPC2	A646V G648S, A646V	Single substitution Double substitution	Q59QC7 Q59QC7	712 712	AF-Q59QC7-F1 AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 68	C. albicans	Clinical isolate	UPC2	A643V	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 69	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
isolate 71	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2012	22923048
CG 10956	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	E2GKZ6	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2012	22948870
CG 14378	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	E2GKZ4	1863	Model		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2012	22948870
CG 2092	C. glabrata	Clinical isolate	FKS1	L630I	Single substitution	E2GKZ4	1863	Model		Anidulafungin (0.5), Caspofungin (1), Micafungin (0.13)	2012	22948870
CG 211	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2012	22948870
CG 4720	C. glabrata	Clinical isolate	FKS2	S645P	Single substitution	E2GKZ6	1897	Model	Mismatch residue	Anidulafungin (4), Caspofungin (8), Micafungin (4)	2012	22948870
CG 4742	C. glabrata	Clinical isolate	FKS2	L632R	Single substitution	E2GKZ6	1897	Model	Mismatch residue	Anidulafungin (0.25), Caspofungin (1), Micafungin (0.5)	2012	22948870
CG 4747	C. glabrata	Clinical isolate	FKS2	L646R	Single substitution	E2GKZ6	1897	Model	Mismatch residue	Anidulafungin (0.06), Caspofungin (1), Micafungin (0.25)	2012	22948870
CG 729	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (8)	2012	22948870
CG 760	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2012	22948870
CG1012	C. glabrata	Clinical isolate	ERG2	I207V	Single substitution	Q6FKL1	224	AF-Q6FKL1-F1		Fluconazole (64), Voriconazole (2), Amphotericin B (2)	2012	23027188
CG388	C. glabrata	Clinical isolate	ERG2	I207V	Single substitution	Q6FKL1	224	AF-Q6FKL1-F1		Fluconazole (64), Voriconazole (2), Amphotericin B (2)	2012	23027188
CG44	C. glabrata	Clinical isolate	ERG2	I207V	Single substitution	Q6FKL1	224	AF-Q6FKL1-F1		Fluconazole (64), Voriconazole (2), Amphotericin B (2)	2012	23027188
CG852	C. glabrata	Clinical isolate	ERG2	I207V, L60F, T121V	Multiple substitution	Q6FKL1	224	AF-Q6FKL1-F1		Fluconazole (128), Voriconazole (2), Amphotericin B (8)	2012	23027188
CG872	C. glabrata	Clinical isolate	ERG2	I207V, T121I	Double substitution	Q6FKL1	224	AF-Q6FKL1-F1		Fluconazole (64), Voriconazole (1), Amphotericin B (8)	2012	23027188
Ca1	C. albicans	Clinical isolate	FKS1	D648Y	Single substitution	O13428	1897	Model		Caspofungin (0.5)	2013	23089746
Ca2	C. albicans	Clinical isolate	FKS1	P649H	Single substitution	O13428	1897	Model		Caspofungin (1)	2013	23089746
Cg	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25) [EUCAST], Caspofungin (4) [CLSI]	2013	23089746
Ct1	C. tropicalis	Clinical isolate	FKS1	F76S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (0.125) [EUCAST], Caspofungin (0.25) [CLSI]	2013	23089746
Ct2	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (0.25)	2013	23089746
Ct3	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (0.25)	2013	23089746
ISOLATE 2( BC-CVC)	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	B6S6L8	1904	Model	Mismatch residue	EUCAST[Anidulafungin (0.25), Micafungin (1)] Etest[Caspofungin (>32)]	2013	23089761
ISOLATE 3(Cavum oris)	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	B6S6L8	1904	Model	Mismatch residue	EUCAST[Anidulafungin (0.5), Micafungin (>1)] Etest[Caspofungin (>32)]	2013	23089761
C. albicans CAI4-R	C. albicans	Laboratory strain	ERG11	Y257H	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (128)	2013	23216650
ISOLATE14	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Itraconazole (2)	2013	23221625
ISOLATE17	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32)	2013	23221625
ISOLATE19	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Itraconazole (1)	2013	23221625
ISOLATE1b	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32)	2013	23221625
ISOLATE25	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Itraconazole (2)	2013	23221625
ISOLATE28	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Itraconazole (2)	2013	23221625
ISOLATE30	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32)	2013	23221625
ISOLATE31	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Itraconazole (1)	2013	23221625
ISOLATE6	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32), Itraconazole (2), Voriconazole (2)	2013	23221625
ISOLATE7	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Itraconazole (2), Voriconazole (2)	2013	23221625
ISOLATE8	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32), Itraconazole (2), Voriconazole (2)	2013	23221625
ISOLATE9	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Itraconazole (1), Voriconazole (4)	2013	23221625
ISOLATE 02	C. albicans	Clinical isolate	ERG11	R467I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2013	23402828
ISOLATE 04	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2013	23402828
ISOLATE 07	C. albicans	Clinical isolate	ERG11	L321F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2013	23402828
isolate 89	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		MIC50[Caspofungin (2), Posaconazole (0.25)], MIC100[Caspofungin (>16), Posaconazole (>16)]	2013	23472097
13139	C. albicans	Clinical isolate	ERG11	Y132F, K143Q, Y257H	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Itraconazole (>16), Voriconazole (8)	2013	23480635
141	C. albicans	Clinical isolate	ERG11	A114S, Y257H, V437I	Multiple substitution	P10613	528	5V5Z		Itraconazole (>16)	2013	23480635
201	C. albicans	Clinical isolate	ERG11	A114S, Y257H, V437I	Multiple substitution	P10613	528	5V5Z		Itraconazole (16)	2013	23480635
206	C. albicans	Clinical isolate	ERG11	A114S, V437I	Double substitution	P10613	528	5V5Z		Itraconazole (16)	2013	23480635
208	C. albicans	Clinical isolate	ERG11	Y132H, N435V, G448E, D502E	Multiple substitution	P10613	528	5V5Z	Structure not available	Itraconazole (16)	2013	23480635
210	C. albicans	Clinical isolate	ERG11	Y132H, Y257H, V437I, G448E	Multiple substitution	P10613	528	5V5Z		Voriconazole (4)	2013	23480635
21897	C. albicans	Clinical isolate	ERG11	Y132F, K143Q, V437I	Multiple substitution	P10613	528	5V5Z		Fluconazole (>64), Itraconazole (>16), Voriconazole (16)	2013	23480635
patient 10(ep 1)	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5), Fluconazole (128)	2013	23487382
patient 3(ep 1)	C. glabrata	Clinical isolate	FKS2	R631G	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Fluconazole (128)	2013	23487382
patient 4(ep 2)	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5), Fluconazole (128)	2013	23487382
patient 5(ep 2)	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5), Fluconazole (128)	2013	23487382
patient 6(ep 2)	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2013	23487382
patient 7(ep 1)	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25), Fluconazole (128)	2013	23487382
patient 7(ep 2)	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25), Fluconazole (128)	2013	23487382
patient 8(ep 1)	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4), Micafungin (0.25), Fluconazole (64)	2013	23487382
patient 8(ep 2)	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2013	23487382
patient 9(ep 1)	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2013	23487382
patient15(ep 2)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.5)	2013	23487382
patient16(ep 2)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (>8), Fluconazole (128)	2013	23487382
patient17(ep 1)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8), Micafungin (0.5)	2013	23487382
patient18(ep 1)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2013	23487382
patient18(ep 2)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4), Fluconazole (128)	2013	23487382
patient19(ep 1)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (8), Micafungin (0.5)	2013	23487382
patient20(ep 1)	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4), Fluconazole (128)	2013	23487382
patient21(ep 2)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (>8), Micafungin (2)	2013	23487382
ISOLATE 1	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Caspofungin (2)	2013	23669387
ISOLATE 102	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (8)	2013	23669387
ISOLATE 129	C. glabrata	Clinical isolate	FKS2	F659L	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2013	23669387
ISOLATE 187	C. glabrata	Clinical isolate	FKS2	F659L	Single substitution	Q6FMZ3	1897	Model		Caspofungin (2)	2013	23669387
ISOLATE 190	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (8)	2013	23669387
ISOLATE 309	C. glabrata	Clinical isolate	FKS1	D632H	Single substitution	Q6FTN8	1863	Model		Caspofungin (2)	2013	23669387
ISOLATE 35	C. glabrata	Clinical isolate	FKS2	F659L	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2013	23669387
ISOLATE 755	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2013	23669387
ISOLATE O-95	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2013	23669387
Ca1	C. albicans	Clinical isolate	FKS1	S654P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Structure not available	Anidulafungin (0.5), Caspofungin (1), Micafungin (1)	2013	23720791
Ca2	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Anidulafungin (0.5), Caspofungin (2), Micafungin (1)	2013	23720791
Ca3	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Structure not available	Anidulafungin (0.25), Caspofungin (1), Micafungin (0.5)	2013	23720791
Cg1	C. glabrata	Clinical isolate	FKS1 FKS2	F625S F641V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (0.25), Caspofungin (0.25) Anidulafungin (1), Caspofungin (4)	2013	23720791
Cg2	C. glabrata	Clinical isolate	FKS2 FKS2	D648E S659Y	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Anidulafungin (0.25), Caspofungin (0.5) Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2013	23720791
Cg3	C. glabrata	Clinical isolate	FKS2 FKS2	F641Y S663Y	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Anidulafungin (0.5), Caspofungin (0.25) Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2013	23720791
Cg4	C. glabrata	Clinical isolate	FKS2 FKS2	L644W S663P	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5) Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2013	23720791
Cg5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2013	23720791
Cg6	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (16), Micafungin (2)	2013	23720791
CG2	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Micafungin (0.5)	2013	23817368
CL-6835	C. tropicalis	Clinical isolate	ERG11 ERG3	G464D S113G	Single substitution Single substitution	P14263 C5MEI7	528 392	AF-P14263-F1 AF-C5MEI7-F1		Amphotericin B (2), Fluconazole (>64), Voriconazole (>8)	2013	23877676
TP-13650	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	P14263	528	AF-P14263-F1		Amphotericin B (0.25), Fluconazole (>64), Voriconazole (>8)	2013	23877676
CAAL28	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	S405F S264P, N896S A451V	Single substitution Double substitution Single substitution	P10613 Q1WCU6 B4YK07	528 981 712	5V5Z AF-Q1WCU6-F1 AF-B4YK07-F1		Fluconazole (64)	2013	24051054
CAAL37	C. albicans	Clinical isolate	ERG11 MRR1 TAC1	G464S N937K, F1032L E841G, N896S	Single substitution Double substitution Double substitution	P10613 Q5A4G2 Q1WCU6	528 1108 981	5V5Z AF-Q5A4G2-F1 AF-Q1WCU6-F1		Fluconazole (>64)	2013	24051054
CAAL61	C. albicans	Clinical isolate	ERG11 MRR1 TAC1 UPC2	G307S, Y447H K884E K87N, M170I, N174D G648S	Double substitution Single substitution Multiple substitution Single substitution	P10613 Q5A4G2 Q1WCU6 B4YK07	528 1108 981 712	5V5Z AF-Q5A4G2-F1 AF-Q1WCU6-F1 AF-B4YK07-F1		Fluconazole (>64)	2013	24051054
CAAL67	C. albicans	Clinical isolate	MRR1 TAC1	N937K, F1032L, S1037L K87N, M170I, N174D, T225A, W442stop, N896S	Multiple substitution Complex	Q5A4G2 Q1WCU6	1108 981	AF-Q5A4G2-F1 AF-Q1WCU6-F1		Fluconazole (32)	2013	24051054
CAAL74	C. albicans	Clinical isolate	ERG11 MRR1 TAC1 UPC2	Y132F, G448V R557K N896S T273A, G648S, K684E	Double substitution Single substitution Single substitution Multiple substitution	P10613 Q5A4G2 Q1WCU6 B4YK07	528 1108 981 712	5V5Z AF-Q5A4G2-F1 AF-Q1WCU6-F1 AF-B4YK07-F1		Fluconazole (>64)	2013	24051054
CAAL75	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y132H, K143R W486C, N896S, G980W T273A	Double substitution Multiple substitution Single substitution	P10613 Q1WCU6 B4YK07	528 981 712	5V5Z AF-Q1WCU6-F1 AF-B4YK07-F1		Fluconazole (>64), Voriconazole (4)	2013	24051054
C102	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (512), Itraconazole (2), Voriconazole (4)	2013	24070847
C112	C. albicans	Clinical isolate	ERG11	T123I, Y132H, L376F	Multiple substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (2), Voriconazole (4)	2013	24070847
C125	C. albicans	Clinical isolate	ERG11	L480F	Single substitution	P10613	528	5V5Z		Fluconazole (128)	2013	24070847
C146	C. albicans	Clinical isolate	ERG11	G346A	Single substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (1), Voriconazole (4)	2013	24070847
C159	C. albicans	Clinical isolate	ERG11	L480F	Single substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (1)	2013	24070847
C16	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (1)	2013	24070847
C163	C. albicans	Clinical isolate	ERG11	A434V	Single substitution	P10613	528	5V5Z		Fluconazole (256)	2013	24070847
C194	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2013	24070847
C211	C. albicans	Clinical isolate	ERG11	L480F	Single substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (1)	2013	24070847
C239	C. albicans	Clinical isolate	ERG11	G346A	Single substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (2), Voriconazole (8)	2013	24070847
C43	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (256), Itraconazole (1)	2013	24070847
C47	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Fluconazole (256), Voriconazole (4)	2013	24070847
C81	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	P10613	528	5V5Z		Fluconazole (128)	2013	24070847
C97	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (1)	2013	24070847
10685J	C. glabrata	Clinical isolate	FKS2	F384Y	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2014	24126582
10700J	C. glabrata	Clinical isolate	FKS2	L662W, E78D, T926P	Multiple substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Anidulafungin (2), Caspofungin (1), Fluconazole (64)	2014	24126582
10702J	C. glabrata	Clinical isolate	FKS1	A995T	Single substitution	Q6FTN8	1863	Model		Caspofungin (0.25)	2014	24126582
10708J	C. glabrata	Clinical isolate	FKS1	A1749V	Single substitution	Q6FTN8	1863	Model		Micafungin (0.06), Anidulafungin (0.25), Caspofungin (0.25)	2014	24126582
10728J	C. glabrata	Clinical isolate	FKS1	D140Y, A1749V	Double substitution	Q6FTN8	1863	Model		Caspofungin (0.25)	2014	24126582
10729J	C. glabrata	Clinical isolate	FKS1	L195F	Single substitution	Q6FTN8	1863	Model		Caspofungin (0.25)	2014	24126582
17823F	C. glabrata	Clinical isolate	FKS2	A450T	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.06), Fluconazole (128)	2014	24126582
2003 JAPAN	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Anidulafungin (1), Caspofungin (8)	2014	24126582
2004 JAPAN	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Anidulafungin (2), Caspofungin (1), Fluconazole (64)	2014	24126582
2004 SPAIN	C. glabrata	Clinical isolate	FKS2 FKS2	L664R L664R	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (0.25), Anidulafungin (1), Caspofungin (0.25), Fluconazole (128) Micafungin (0.25), Anidulafungin (1), Caspofungin (0.5), Fluconazole (64)	2014	24126582
2005 GERMANY	C. glabrata	Clinical isolate	FKS2	D666Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.06), Caspofungin (0.25)	2014	24126582
2005 OHIO	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.12), Anidulafungin (1), Caspofungin (1)	2014	24126582
2006 GERMANY	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.06), Anidulafungin (0.5), Caspofungin (0.5)	2014	24126582
2006 VIRGINIA	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.12), Anidulafungin (1), Caspofungin (2), Fluconazole (128)	2014	24126582
2007 INDIANA	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.06), Anidulafungin (0.25), Caspofungin (0.25)	2014	24126582
2008 GERMANY	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Anidulafungin (1), Caspofungin (1), Fluconazole (64)	2014	24126582
2008 INDIANA	C. glabrata	Clinical isolate	FKS1 FKS2	S629P, R631S S663P	Double substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (16), Anidulafungin (4), Caspofungin (2) Micafungin (4), Anidulafungin (4), Caspofungin (16)	2014	24126582
2008 OHIO	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (1), Anidulafungin (2), Caspofungin (16), Fluconazole (128)	2014	24126582
2008 WASHINGTON	C. glabrata	Clinical isolate	FKS1 FKS1 FKS2	D632Y S629P S663F	Single substitution Single substitution Single substitution	Q6FTN8 Q6FTN8 Q6FMZ3	1863 1863 1897	Model Model Model		Anidulafungin (0.25), Caspofungin (0.12), Fluconazole (128) Micafungin (0.5), Anidulafungin (2), Caspofungin (16) Micafungin (0.12), Anidulafungin (0.5), Caspofungin (0.25)	2014	24126582
2009 GERMANY	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.06), Anidulafungin (1), Caspofungin (0.5), Fluconazole (128)	2014	24126582
2010 GERMANY	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Anidulafungin (1), Caspofungin (0.5)	2014	24126582
2010 OHIO	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.12), Anidulafungin (0.5), Caspofungin (0.25)	2014	24126582
2010 TEXAS	C. glabrata	Clinical isolate	FKS1	F625Y	Single substitution	Q6FTN8	1863	Model		Micafungin (0.03), Anidulafungin (0.25), Caspofungin (0.12)	2014	24126582
2011 AUSTRALIA	C. glabrata	Clinical isolate	FKS1 FKS2	F625S S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (0.12), Anidulafungin (1), Caspofungin (0.5), Fluconazole (128) Micafungin (2), Anidulafungin (2), Caspofungin (2), Fluconazole (128)	2014	24126582
2011 CANADA	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Anidulafungin (1), Caspofungin (2)	2014	24126582
2011 GREECE	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Anidulafungin (4), Caspofungin (4)	2014	24126582
2011 INDIANA	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Anidulafungin (1), Caspofungin (0.5)	2014	24126582
2011 LOUSIANA	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (4), Anidulafungin (2), Caspofungin (16), Fluconazole (128)	2014	24126582
2011 NEWYORK	C. glabrata	Clinical isolate	FKS2	P1371S	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.03), Caspofungin (0.25)	2014	24126582
37706F	C. glabrata	Clinical isolate	FKS2	S663Y, G680S	Double substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Anidulafungin (1), Caspofungin (0.5)	2014	24126582
44075F	C. glabrata	Clinical isolate	FKS2	T926P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.12), Micafungin (0.03)	2014	24126582
46228A	C. glabrata	Clinical isolate	FKS1 FKS2	Y1279F T926P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (0.25), Fluconazole (128)	2014	24126582
49079F	C. glabrata	Clinical isolate	FKS2	S663P, T926P	Double substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2), Caspofungin (2), Fluconazole (>128)	2014	24126582
49889F	C. glabrata	Clinical isolate	FKS2	G680S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2014	24126582
760F	C. glabrata	Clinical isolate	FKS2	S663F, T926P	Double substitution	Q6FMZ3	1897	Model		Micafungin (0.12), Anidulafungin (0.5), Caspofungin (0.25)	2014	24126582
CA1	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Micafungin (1), Caspofungin (2)	2014	24153129
CA2	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Micafungin (2), Caspofungin (2)	2014	24153129
CA3	C. albicans	Clinical isolate	FKS1	F641Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2014	24153129
CA4	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin (1), Caspofungin (1)	2014	24153129
CA5	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2014	24153129
CA6	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin (2), Caspofungin (2)	2014	24153129
CA7	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin (2), Caspofungin (1)	2014	24153129
CG1	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Caspofungin (0.5)	2014	24153129
CG10	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG11	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG12	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (8)	2014	24153129
CG13	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Caspofungin (2)	2014	24153129
CG14	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (4)	2014	24153129
CG15	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (2)	2014	24153129
CG16	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2014	24153129
CG17	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (2)	2014	24153129
CG18	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (1)	2014	24153129
CG19	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (0.5)	2014	24153129
CG2	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Micafungin (0.5), Caspofungin (2)	2014	24153129
CG20	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (1)	2014	24153129
CG21	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (16)	2014	24153129
CG22	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Caspofungin (2)	2014	24153129
CG23	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Caspofungin (4)	2014	24153129
CG24	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (2)	2014	24153129
CG25	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin ()16), Caspofungin (16)	2014	24153129
CG26	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (8)	2014	24153129
CG27	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG28	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (16)	2014	24153129
CG29	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (8)	2014	24153129
CG3	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Micafungin (0.5), Caspofungin (2)	2014	24153129
CG30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG31	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (16)	2014	24153129
CG32	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (8)	2014	24153129
CG33	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (1)	2014	24153129
CG34	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (16)	2014	24153129
CG35	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Caspofungin (0.5)	2014	24153129
CG36	C. glabrata	Clinical isolate	FKS2	L664R	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG37	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG38	C. glabrata	Clinical isolate	FKS2	R665S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24153129
CG39	C. glabrata	Clinical isolate	FKS2	D666Y	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2014	24153129
CG4	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (1), Caspofungin (16)	2014	24153129
CG40	C. glabrata	Clinical isolate	FKS2	P667F	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2014	24153129
CG41	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Caspofungin (16)	2014	24153129
CG42	C. glabrata	Clinical isolate	FKS2	P1371S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2014	24153129
CG5	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (0.5), Caspofungin (16)	2014	24153129
CG6	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (4), Caspofungin (16)	2014	24153129
CG7	C. glabrata	Clinical isolate	FKS1	S629P, R631S	Double substitution	Q6FTN8	1863	Model		Micafungin (16), Caspofungin (2)	2014	24153129
CG8	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25), Caspofungin (0.5)	2014	24153129
CG9	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25), Caspofungin (1)	2014	24153129
CK1	C. krusei	Clinical isolate	FKS1	F655C	Single substitution	Q4U2W2	1885	Model		Caspofungin (1)	2014	24153129
CK2	C. krusei	Clinical isolate	FKS1	R1361G	Single substitution	Q4U2W2	1885	Model	Mismatch residue	Micafungin (2), Caspofungin (16)	2014	24153129
CT1	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Micafungin (1), Caspofungin (1)	2014	24153129
CT2	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Micafungin (1), Caspofungin (2)	2014	24153129
CT3	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Micafungin (1), Caspofungin (2)	2014	24153129
DPL1007	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1), Ibrexafungerp (MK-3118) (1)	2014	24323472
DPL1008	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Ibrexafungerp (MK-3118) (1)	2014	24323472
DPL1009	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Ibrexafungerp (MK-3118) (0.12)	2014	24323472
DPL1010	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Ibrexafungerp (MK-3118) (0.12)	2014	24323472
DPL1011	C. albicans	Clinical isolate	FKS1	S645F, R1361H	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2), Ibrexafungerp (MK-3118) (<0.03)	2014	24323472
DPL1013	C. albicans	Clinical isolate	FKS1	P649H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.25), Ibrexafungerp (MK-3118) (0.25)	2014	24323472
DPL155	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (4), Ibrexafungerp (MK-3118) (2)	2014	24323472
DPL18	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.5), Ibrexafungerp (MK-3118) (1)	2014	24323472
DPL20	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Ibrexafungerp (MK-3118) (0.5)	2014	24323472
DPL23	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (>16), Ibrexafungerp (MK-3118) (4)	2014	24323472
DPL236	C. glabrata	Clinical isolate	FKS1	L664R	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Caspofungin (1), Ibrexafungerp (MK-3118) (0.5)	2014	24323472
DPL26	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (>16), Ibrexafungerp (MK-3118) (0.50)	2014	24323472
DPL30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (>16), Ibrexafungerp (MK-3118) (0.50)	2014	24323472
DPL33	C. glabrata	Clinical isolate	FKS2	D666E	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (2), Ibrexafungerp (MK-3118) (0.25)	2014	24323472
DPL34	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (2), Ibrexafungerp (MK-3118) (0.5)	2014	24323472
DPL38	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Caspofungin (2), Ibrexafungerp (MK-3118) (4)	2014	24323472
DPL39	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Caspofungin (16), Ibrexafungerp (MK-3118) (0.5)	2014	24323472
DPL41	C. glabrata	Clinical isolate	FKS1	D632G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Caspofungin (2), Ibrexafungerp (MK-3118) (0.5)	2014	24323472
DPL42	C. glabrata	Clinical isolate	FKS1	D632G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Caspofungin (16), Ibrexafungerp (MK-3118) (8)	2014	24323472
8622 A	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Fluconazole (>64), Voriconazole (4), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2014	24468776
8622 B	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Fluconazole (>64), Voriconazole (4), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2014	24468776
8622 C	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Fluconazole (>64), Voriconazole (4), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2014	24468776
8622 D	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Fluconazole (>64), Voriconazole (4), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2014	24468776
8622 E	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	E2GKZ6	1897	Model		Fluconazole (>64), Voriconazole (4), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2014	24468776
ISOLATE 100	C. glabrata	Clinical isolate	FKS2	F708V	Single substitution	E2GKZ6	1897	Model		Caspofungin (0.5)	2014	24522619
ISOLATE 120	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	E2GKZ6	1897	Model		Caspofungin (16)	2014	24522619
ISOLATE 177	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	E2GKZ6	1897	Model		Caspofungin (1)	2014	24522619
CaB	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (2), Anidulafungin (1)	2014	24715154
CaO	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (1)	2014	24715154
CaS	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (2)	2014	24715154
CgO	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1), Micafungin (0.5), Anidulafungin (2)	2014	24715154
CgU	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1), Micafungin (0.25), Anidulafungin (1)	2014	24715154
CkB	C. kefyr	Clinical isolate	FKS1	F641P	Single substitution	W0TDH9	1892	Model		Caspofungin (2), Micafungin (4), Anidulafungin (2)	2014	24715154
CkO	C. krusei	Clinical isolate	FKS1	L701M	Single substitution	Q4U2W2	1885	Model		Caspofungin (1)	2014	24715154
111.12	C. albicans	Clinical isolate	FKS1	R647G, P649L	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		EUCAST[Micafungin (1), Voriconazole (4), Fluconazole (>16)], Etest[Caspofungin (2)]	2014	24733467
RRCL 110.12	C. albicans	Clinical isolate	FKS1	R647G, P649L	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		EUCAST[Micafungin (1), Voriconazole (4), Fluconazole (>16)], Etest[Caspofungin (2)]	2014	24733467
FMR 8489	C. glabrata	Clinical isolate	FKS2	L707S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.12)	2014	24733474
FMR 8498	C. glabrata	Clinical isolate	FKS2	L707S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.12)	2014	24733474
JMI-10956	C. glabrata	Clinical isolate	FKS2	F659V, L707S	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (1) [EUCAST] Caspofungin (2) [CLSI]	2014	24733474
JMI-127	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2) [EUCAST] Caspofungin (16) [CLSI]	2014	24733474
JMI-14378	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2) [EUCAST] Caspofungin (4) [CLSI]	2014	24733474
JMI-206	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) [EUCAST] Caspofungin (1) [CLSI]	2014	24733474
JMI-2092	C. glabrata	Clinical isolate	FKS2	L707S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5) [EUCAST Caspofungin (1) [CLSI]	2014	24733474
JMI-211	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) [EUCAST] Caspofungin (1) [CLSI]	2014	24733474
JMI-297	C. glabrata	Clinical isolate	FKS1	S629P, R631S, A1037T	Multiple substitution	Q6FTN8	1863	Model		Anidulafungin (1) [EUCAST] Caspofungin (1) [CLSI]	2014	24733474
JMI-729	C. glabrata	Clinical isolate	FKS2	F663P	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (4) [EUCAST] Caspofungin (>16) [CLSI]	2014	24733474
JMI-760	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) [EUCAST] Caspofungin (1) [CLSI]	2014	24733474
UTHSC 10461	C. glabrata	Clinical isolate	FKS2	L707S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24733474
20.551.099	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2014	24829248
20.593.033	C. glabrata	Clinical isolate	FKS1 FKS2	W645stop S663P	Stop Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2014	24829248
21900	C. glabrata	Clinical isolate	FKS1	D632G	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (4)	2014	24829248
3.83 0	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>8), Micafungin (1)	2014	24829248
31498	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8), Micafungin (4)	2014	24829248
3169	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (2)	2014	24829248
37178	C. glabrata	Clinical isolate	FKS1 FKS2	W645stop S663P	Stop Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (>8), Micafungin (8)	2014	24829248
42971	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (4), Micafungin (1)	2014	24829248
42997	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2014	24829248
5847	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (2)	2014	24829248
6183	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2014	24829248
LMDM 34	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>8), Micafungin (2)	2014	24829248
LMDM 37	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (4), Micafungin (4)	2014	24829248
M234	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4), Micafungin (1)	2014	24829248
M2791	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (4), Micafungin (4)	2014	24829248
M2798	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (8), Caspofungin (>8), Micafungin (8)	2014	24829248
IUM 09-0233	C. krusei	Clinical isolate	FKS1	A647T, L701M	Double substitution	Q4U2W2	1885	Model		Anidulafungin (0.25), Caspofungin (4), Micafungin (4), Fluconazole (16)	2014	24858652
RclinD35	C. krusei	Clinical isolate	ERG11	Y132H	Single substitution	A9YUC7	528	AF-A9YUC7-F1	Mismatch residue	Voriconazole (4)	2014	24867987
RclinD84	C. krusei	Clinical isolate	ERG11	Y132H	Single substitution	A9YUC7	528	AF-A9YUC7-F1	Mismatch residue	Voriconazole (4)	2014	24867987
patient 10	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Caspofungin (8)	2014	24879785
patient 6	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24879785
patient 7	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8)	2014	24879785
patient 8	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8)	2014	24879785
patient 9	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8)	2014	24879785
Cg1	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.125)	2014	24890592
Cg10	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2014	24890592
Cg11	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25)	2014	24890592
Cg12	C. glabrata	Clinical isolate	FKS1	D632V	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2014	24890592
Cg13	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2014	24890592
Cg14	C. glabrata	Clinical isolate	FKS1	I634V	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25)	2014	24890592
Cg15	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2014	24890592
Cg16	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (1), Micafungin (0.25)	2014	24890592
Cg17	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2)	2014	24890592
Cg18	C. glabrata	Clinical isolate	FKS1 FKS2	R631G D666V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (0.5), Micafungin (0.5)	2014	24890592
Cg19	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Micafungin (0.5), Fluconazole (128)	2014	24890592
Cg2	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.25)	2014	24890592
Cg20	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.5), Fluconazole (128)	2014	24890592
Cg21	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (0.5)	2014	24890592
Cg22	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2014	24890592
Cg23	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Caspofungin (0.5), Micafungin (1)	2014	24890592
Cg24	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (8), Micafungin (1), Fluconazole (256)	2014	24890592
Cg25	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (2), Caspofungin (4), Micafungin (1), Fluconazole (64)	2014	24890592
Cg26	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (1), Fluconazole (64)	2014	24890592
Cg27	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4), Micafungin (1), Fluconazole (64)	2014	24890592
Cg28	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2014	24890592
Cg29	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (1), Micafungin (2)	2014	24890592
Cg3	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.5), Fluconazole (64)	2014	24890592
Cg30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (8), Micafungin (2), Fluconazole (128)	2014	24890592
Cg31	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (2), Fluconazole (128)	2014	24890592
Cg32	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (2), Fluconazole (128)	2014	24890592
Cg33	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (2), Fluconazole (64)	2014	24890592
Cg34	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2014	24890592
Cg35	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2014	24890592
Cg36	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (2)	2014	24890592
Cg37	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2014	24890592
Cg38	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (16), Micafungin (2)	2014	24890592
Cg39	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2014	24890592
Cg4	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Fluconazole (64)	2014	24890592
Cg40	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (2)	2014	24890592
Cg41	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2014	24890592
Cg42	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8), Micafungin (4)	2014	24890592
Cg43	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (16), Micafungin (4), Fluconazole (256)	2014	24890592
Cg44	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (16), Micafungin (4), Fluconazole (256)	2014	24890592
Cg45	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (4), Fluconazole (128)	2014	24890592
Cg46	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>16), Micafungin (4), Fluconazole (64)	2014	24890592
Cg47	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (4)	2014	24890592
Cg48	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (4)	2014	24890592
Cg5	C. glabrata	Clinical isolate	FKS2	P667H	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2014	24890592
Cg6	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25), Fluconazole (256)	2014	24890592
Cg7	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2), Micafungin (0.25), Fluconazole (256)	2014	24890592
Cg8	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25), Fluconazole (64)	2014	24890592
Cg9	C. glabrata	Clinical isolate	FKS2	R663F	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (2), Caspofungin (2), Micafungin (0.25), Fluconazole (64)	2014	24890592
ISOLATE NO 02	C. albicans	Clinical isolate	ERG11	R467I	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2014	24930991
ISOLATE NO 11	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2014	24930991
ISOLATE NO 25	C. albicans	Clinical isolate	ERG11	L321F	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2014	24930991
C. kefyr PAZ	C. kefyr	Clinical isolate	ERG11	E123Q, K151E	Double substitution	W8NYE2	526	AF-W8NYE2-F1		Fluconazole (>256), Voriconazole (>32)	2014	24936404
Ca1	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Anidulafungin (1), Caspofungin (2)	2014	24951808
Ca2	C. albicans	Clinical isolate	FKS1	F641Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2014	24951808
Ca3	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Caspofungin (2)	2014	24951808
Ca4	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Caspofungin (1)	2014	24951808
Cg1	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg10	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.5)	2014	24951808
Cg11	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg12	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (8)	2014	24951808
Cg13	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2014	24951808
Cg14	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4)	2014	24951808
Cg15	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2014	24951808
Cg16	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2014	24951808
Cg17	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2014	24951808
Cg18	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1)	2014	24951808
Cg19	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg2	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2)	2014	24951808
Cg20	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2014	24951808
Cg21	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2014	24951808
Cg22	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2014	24951808
Cg23	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16)	2014	24951808
Cg24	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2)	2014	24951808
Cg25	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (4)	2014	24951808
Cg26	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2014	24951808
Cg27	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16)	2014	24951808
Cg28	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8)	2014	24951808
Cg29	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24951808
Cg3	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2)	2014	24951808
Cg30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16)	2014	24951808
Cg31	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (8)	2014	24951808
Cg32	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24951808
Cg33	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16)	2014	24951808
Cg34	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (8)	2014	24951808
Cg35	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2014	24951808
Cg36	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16)	2014	24951808
Cg37	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg38	C. glabrata	Clinical isolate	FKS2	L664R	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg39	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24951808
Cg4	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (16)	2014	24951808
Cg40	C. glabrata	Clinical isolate	FKS2	R665S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2014	24951808
Cg41	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2014	24951808
Cg42	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (16)	2014	24951808
Cg5	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (16)	2014	24951808
Cg6	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (16)	2014	24951808
Cg7	C. glabrata	Clinical isolate	FKS1	S629P, R631S	Double substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (2)	2014	24951808
Cg8	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (0.5)	2014	24951808
Cg9	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1)	2014	24951808
Ckru1	C. krusei	Clinical isolate	FKS1	F655C	Single substitution	Q4U2W2	1885	Model		Caspofungin (1)	2014	24951808
Ckru2	C. krusei	Clinical isolate	FKS1	R1361G	Single substitution	Q4U2W2	1885	Model	Mismatch residue	Anidulafungin (1), Caspofungin (16)	2014	24951808
Ct1	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	C5MFG3	1570	Model	Mismatch residue	Anidulafungin (1), Caspofungin (1)	2014	24951808
Ct2	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5MFG3	1570	Model	Structure not available	Anidulafungin (1), Caspofungin (2)	2014	24951808
Ct3	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5MFG3	1570	Model	Structure not available	Caspofungin (2)	2014	24951808
C113	C. kefyr	Clinical isolate	FKS1	R647G	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.25), Caspofungin (0.125), Micafungin (4)	2014	24982083
C116	C. kefyr	Clinical isolate	FKS1	F641del	Deletion	Not available	Not available	Not available	Structure not available	Anidulafungin (>8.0), Caspofungin (4), Micafungin (>8)	2014	24982083
C132	C. kefyr	Clinical isolate	FKS1	S645P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (>8), Caspofungin (2), Micafungin (>8)	2014	24982083
C133	C. kefyr	Clinical isolate	FKS1	S645P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (>8), Caspofungin (2), Micafungin (>8)	2014	24982083
C134	C. kefyr	Clinical isolate	FKS1	S645P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (>8), Caspofungin (2), Micafungin (>8)	2014	24982083
C135	C. kefyr	Clinical isolate	FKS1	S645P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (>8), Caspofungin (2), Micafungin (>8)	2014	24982083
C136	C. kefyr	Clinical isolate	FKS1	S645P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (>8), Caspofungin (2), Micafungin (>8)	2014	24982083
Ca	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (>32), Micafungin (>1), Anidulafungin (1.5)	2014	25025677
PATIENT 11	C. orthopsilosis	Clinical isolate	FKS1	P660A	Single substitution	H8X1R5	1902	Model	Mismatch residue	Caspofungin (1), Anidulafungin (0.5), Micafungin (0.5)	2014	25108876
PATIENT 12	C. orthopsilosis	Clinical isolate	FKS1	P660A	Single substitution	H8X1R5	1902	Model	Mismatch residue	Caspofungin (2), Micafungin (2), Anidulafungin (2)	2014	25108876
PATIENT 15	C. orthopsilosis	Clinical isolate	FKS1	P660A	Single substitution	H8X1R5	1902	Model	Mismatch residue	Caspofungin (8), Micafungin (2), Anidulafungin (2)	2014	25108876
PATIENT 4	C. parapsilosis	Clinical isolate	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Caspofungin (1), Micafungin (2), Anidulafungin (2)	2014	25108876
PATIENT 5	C. parapsilosis	Clinical isolate	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Caspofungin (0.5), Anidulafungin (1), Micafungin (1)	2014	25108876
PATIENT 9	C. parapsilosis	Clinical isolate	FKS1	P660A	Single substitution	A9YLC3	1909	Model	Mismatch residue	Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2014	25108876
Cd	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	D3IZZ7	1897	Model	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (1)	2014	25129315
Cg1	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (0.5)	2014	25129315
Cg2	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2014	25129315
Cg3	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (1)	2014	25129315
Cg4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (0.5), Micafungin (1)	2014	25129315
Ckef	C. kefyr	Clinical isolate	FKS1	R1344S	Single substitution	W0TDH9	1892	Model	Mismatch residue	Anidulafungin (2), Caspofungin (0.5), Micafungin (1)	2014	25129315
Ckru	C. krusei	Clinical isolate	FKS1	L701M	Single substitution	Q4U2W2	1885	Model		Anidulafungin (1), Caspofungin (1)	2014	25129315
Cg	C. glabrata	Clinical isolate	PDR1	D243N	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1), Posaconazole (16), Prochloraz (64)	2014	25132632
SH131/128-2	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (4)	2015	25351710
SH149	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH174	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH22	C. albicans	Clinical isolate	ERG11	Y132H, G448R	Double substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH37	C. albicans	Clinical isolate	ERG11	V332L	Single substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH42	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH50	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH52/43-2	C. albicans	Clinical isolate	ERG11	V332L	Single substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH54	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Fluconazole (128), Itraconazole (4)	2015	25351710
SH58	C. albicans	Clinical isolate	ERG11	G465S	Single substitution	P10613	528	5V5Z		Itraconazole (4)	2015	25351710
SH59	C. albicans	Clinical isolate	ERG11	V332L	Single substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
SH70	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Voriconazole (8), Fluconazole (128), Itraconazole (4)	2015	25351710
10	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Fluconazole (16)	2014	25385095
13	C. albicans	Clinical isolate	ERG11 UPC2	K143R A643T	Single substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (16)	2014	25385095
15	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (16)	2014	25385095
16	C. albicans	Clinical isolate	ERG11	Q21R	Single substitution	P10613	528	5V5Z		Fluconazole (16)	2014	25385095
17	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (32)	2014	25385095
18	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (32)	2014	25385095
21	C. albicans	Clinical isolate	ERG11 UPC2	A114V, H283R G648D	Double substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (32)	2014	25385095
22	C. albicans	Clinical isolate	ERG11	F145L	Single substitution	P10613	528	5V5Z		Fluconazole (32)	2014	25385095
23	C. albicans	Clinical isolate	ERG11	I483V	Single substitution	P10613	528	5V5Z		Fluconazole (32)	2014	25385095
25	C. albicans	Clinical isolate	ERG11 UPC2	D446E G648S	Single substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (32)	2014	25385095
26	C. albicans	Clinical isolate	ERG11	G307S	Single substitution	P10613	528	5V5Z		Fluconazole (32)	2014	25385095
27	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
28	C. albicans	Clinical isolate	UPC2	W478C	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
29	C. albicans	Clinical isolate	ERG11	Y132F, F145L	Double substitution	P10613	528	5V5Z		Fluconazole (64)	2014	25385095
30	C. albicans	Clinical isolate	ERG11 UPC2	F126L, Y132F A643V	Double substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
31	C. albicans	Clinical isolate	ERG11	G448E	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2014	25385095
32	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (64)	2014	25385095
33	C. albicans	Clinical isolate	ERG11 UPC2	F145L Y642F	Single substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
34	C. albicans	Clinical isolate	UPC2	Y642F	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
35	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
38	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (64)	2014	25385095
40	C. albicans	Clinical isolate	ERG11	F449V	Single substitution	P10613	528	5V5Z		Fluconazole (128)	2014	25385095
43	C. albicans	Clinical isolate	ERG11	D278N, G464S	Double substitution	P10613	528	5V5Z		Fluconazole (128)	2014	25385095
45	C. albicans	Clinical isolate	ERG11 UPC2	G464S A646V	Single substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (128)	2014	25385095
46	C. albicans	Clinical isolate	ERG11	G307S, L403F, G448R	Multiple substitution	P10613	528	5V5Z		Fluconazole (128)	2014	25385095
47	C. albicans	Clinical isolate	ERG11 UPC2	A114V, Y132F, V437I G648D	Multiple substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (128)	2014	25385095
48	C. albicans	Clinical isolate	ERG11	Y132F	Single substitution	P10613	528	5V5Z		Fluconazole (256)	2014	25385095
49	C. albicans	Clinical isolate	ERG11	G307S, V437I, Y447S	Multiple substitution	P10613	528	5V5Z		Fluconazole (256)	2014	25385095
50	C. albicans	Clinical isolate	ERG11	Y132F, K143R	Double substitution	P10613	528	5V5Z		Fluconazole (256)	2014	25385095
52	C. albicans	Clinical isolate	UPC2	G648D	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (256)	2014	25385095
55	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
56	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
57	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
58	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
59	C. albicans	Clinical isolate	ERG11 UPC2	Y132F, T229A, F449L G648D	Multiple substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
65	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
67	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
68	C. albicans	Clinical isolate	ERG11 UPC2	Y132F, I471M, I483V T273A, A643V	Multiple substitution Double substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
69	C. albicans	Clinical isolate	UPC2	G648S	Single substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
70	C. albicans	Clinical isolate	ERG11 UPC2	M258L, G464S A646V	Double substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
71	C. albicans	Clinical isolate	ERG11 UPC2	Y132F, V437I, F449L G648D	Multiple substitution Single substitution	P10613 Q59QC7	528 712	5V5Z AF-Q59QC7-F1		Fluconazole (>256)	2014	25385095
72	C. albicans	Clinical isolate	ERG11	A114V, D153E	Double substitution	P10613	528	5V5Z		Fluconazole (>256)	2014	25385095
BMU05457	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>64)	2015	25398256
C26	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Fluconazole (>128), Itraconazole (>2)	2015	25398256
CAS08-0060	C. parapsilosis	Clinical isolate	MRR1	G53A	Single substitution	G8BAV4	1128	AF-G8BAV4-F1	Mismatch residue	Fluconazole (16)	2015	25451046
CAS08-0339	C. parapsilosis	Clinical isolate	MRR1	A859T	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
CAS08-0490	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16), Voriconazole (1)	2015	25451046
CAS08-0796	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS09-0912	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS09-0959	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (32), Voriconazole (1)	2015	25451046
CAS09-1107	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS09-1291	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16), Voriconazole (1)	2015	25451046
CAS09-1299	C. parapsilosis	Clinical isolate	MRR1	A619V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
CAS09-1321	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (64), Voriconazole (1)	2015	25451046
CAS09-1504	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (32), Voriconazole (2)	2015	25451046
CAS09-1783	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	25451046
CAS10-1830	C. parapsilosis	Clinical isolate	MRR1 MRR1	K177N Q1053X	Single substitution Single substitution	G8BAV4 G8BAV4	1128 1128	AF-G8BAV4-F1 AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
CAS10-1852	C. parapsilosis	Clinical isolate	MRR1	R405K	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
CAS10-1966	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS10-2364	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	25451046
CAS10-2602	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS11-3037	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	25451046
CAS11-3108	C. parapsilosis	Clinical isolate	MRR1	D615G	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
CAS11-3324	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16), Voriconazole (1)	2015	25451046
CAS11-3362	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS12-3954	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	25451046
CAS12-3992	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	25451046
CAS12-4342	C. parapsilosis	Clinical isolate	MRR1	L779F	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32)	2015	25451046
CAS12-4406	C. parapsilosis	Clinical isolate	MRR1	K177N	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2015	25451046
H13139	C. albicans	Clinical isolate	ERG11	Y132F, K143Q, Y257H	Multiple substitution	Q5I4C6	528	AF-Q5I4C6-F1		Fluconazole (>64), Itraconazole (>16), Voriconazole (8)	2015	25748216
H21897	C. albicans	Clinical isolate	ERG11	Y132F, K143Q	Double substitution	Q5I4C6	528	AF-Q5I4C6-F1		Fluconazole (>64), Itraconazole (>16), Voriconazole (16)	2015	25748216
H64110	C. albicans	Clinical isolate	ERG11	Y132F, K143Q, Y257H	Multiple substitution	Q5I4C6	528	AF-Q5I4C6-F1		Fluconazole (>64), Itraconazole (16), Voriconazole (4)	2015	25748216
Y141	C. albicans	Clinical isolate	ERG11 TAC1	A114S, Y257H A736V	Double substitution Single substitution	Q5I4C6 Q1WCU6	528 981	AF-Q5I4C6-F1 AF-Q1WCU6-F1		Itraconazole (>16)	2015	25748216
Y201	C. albicans	Clinical isolate	ERG11 TAC1	A114S, Y257H A736V	Double substitution Single substitution	Q5I4C6 Q1WCU6	528 981	AF-Q5I4C6-F1 AF-Q1WCU6-F1		Itraconazole (16)	2015	25748216
Y206	C. albicans	Clinical isolate	ERG11	Y132H	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1		Itraconazole (16)	2015	25748216
Y208	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	Q5I4C6	528	AF-Q5I4C6-F1		Itraconazole (16)	2015	25748216
Y210	C. albicans	Clinical isolate	ERG11	Y132F, Y257H, G448E	Multiple substitution	Q5I4C6	528	AF-Q5I4C6-F1		Voriconazole (4)	2015	25748216
1031LL	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (2), Micafungin (1), Caspofungin (1)	2015	25779577
1064LL	C. parapsilosis	Clinical isolate	FKS1	M1328I	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (2)	2015	25779577
462LL	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
474LL	C. parapsilosis	Clinical isolate	FKS1	M1328I	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
544LL	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
681LL	C. parapsilosis	Clinical isolate	FKS1	A1422G	Single substitution	A9YLC3	1909	Model		Anidulafungin (2), Micafungin (1), Caspofungin (1)	2015	25779577
713LL	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
831LL	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (2), Micafungin (1), Caspofungin (1)	2015	25779577
928LL	C. parapsilosis	Clinical isolate	FKS1	V595I	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
AX-32	C. parapsilosis	Clinical isolate	FKS1	S745L	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
ST-14	C. parapsilosis	Clinical isolate	FKS1	F1386S	Single substitution	A9YLC3	1909	Model		Anidulafungin (1), Micafungin (1), Caspofungin (1)	2015	25779577
2762	C. glabrata	Clinical isolate	FKS1	F641S	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (4), Micafungin (1)	2015	25878347
A15	C. glabrata	Clinical isolate	FKS1	S645P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (4), Micafungin (0.5)	2015	25878347
A15-10	C. glabrata	Clinical isolate	FKS1	S645P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (2), Caspofungin (8), Micafungin (4)	2015	25878347
M119	C. glabrata	Clinical isolate	FKS1	F641L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (2)	2015	25878347
M121	C. glabrata	Clinical isolate	FKS1	R1361H	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (2)	2015	25878347
M122	C. glabrata	Clinical isolate	FKS1	P649H	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (2.52)	2015	25878347
M149	C. glabrata	Clinical isolate	FKS1	D648Y	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (4), Caspofungin (4), Micafungin (2.52)	2015	25878347
M177	C. glabrata	Clinical isolate	FKS1	F641S	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (4), Micafungin (1)	2015	25878347
M194	C. glabrata	Clinical isolate	FKS1	S645F, R1361H	Double substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (4), Caspofungin (4), Micafungin (2.67)	2015	25878347
M205	C. glabrata	Clinical isolate	FKS1	S645P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (1.26), Caspofungin (8), Micafungin (4)	2015	25878347
M85	C. glabrata	Clinical isolate	FKS1	S645F	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (1.5), Caspofungin (2), Micafungin (2.52)	2015	25878347
M89	C. glabrata	Clinical isolate	FKS1	S645Y	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (2), Caspofungin (4), Micafungin (4)	2015	25878347
M90	C. glabrata	Clinical isolate	FKS1	R1361H	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Caspofungin (1), Micafungin (0.5)	2015	25878347
CG-Australia1	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (≥0.5), Caspofungin (≥0.5), Micafungin (≥0.5)	2015	25899126
CG-Australia2	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5)	2015	25899126
P4	C. albicans	Clinical isolate	ERG11 TAC1	G307S R688Q	Single substitution Single substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (8)	2015	26017038
P5	C. albicans	Clinical isolate	ERG11 TAC1	A61E, G307S R673L	Double substitution Single substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (>16), Itraconazole (16), Voriconazole (1), Posaconazole (>4)	2015	26017038
P7	C. albicans	Clinical isolate	ERG11 FKS1 TAC1	A61E, G307S S645P R673L	Double substitution Single substitution Single substitution	P10613 A0A1D8PCT0 A0A1D8PN96	528 1897 981	5V5Z AF-A0A1D8PCT0-F1 AF-A0A1D8PN96-F1		Fluconazole (>16), Itraconazole (16), Voriconazole (0.25), Posaconazole (4), Anidulafungin (1) [EUCAST] Caspofungin (>32) [Etest]	2015	26017038
P8	C. albicans	Clinical isolate	ERG11 ERG2 FKS1 TAC1	A61E, G307S F105fs S645P R673L	Double substitution Frameshift Single substitution Single substitution	P10613 A0A1D8PCB9 A0A1D8PCT0 A0A1D8PN96	528 217 1897 981	5V5Z AF-A0A1D8PCB9-F1 AF-A0A1D8PCT0-F1 AF-A0A1D8PN96-F1		Fluconazole (>16), Itraconazole (16), Voriconazole (0.125), Posaconazole (4), Anidulafungin (1) [EUCAST] Caspofungin (>32), Amphotericin B (>32) [Etest]	2015	26017038
P9	C. albicans	Clinical isolate	ERG11 ERG2 FKS1 TAC1	A61E, G307S F105fs S645P R673L	Double substitution Frameshift Single substitution Single substitution	P10613 A0A1D8PCB9 A0A1D8PCT0 A0A1D8PN96	528 217 1897 981	5V5Z AF-A0A1D8PCB9-F1 AF-A0A1D8PCT0-F1 AF-A0A1D8PN96-F1		Fluconazole (>16), Itraconazole (16), Voriconazole (0.125), Posaconazole (0.5-4), Anidulafungin (1) [EUCAST] Caspofungin (>32), Amphotericin B (>32) [Etest]	2015	26017038
CA-GRE-TOP	C. albicans	Clinical isolate	ERG3 ERG3	D103N D103N	Single substitution Single substitution	Q59VG6 Q59VG6	386 386	AF-Q59VG6-F1 AF-Q59VG6-F1		Antifungal Echinocandin	2015	26017039
CA-HM-MAC1	C. albicans	Clinical isolate	ERG3	W228Stop	Stop	Q59VG6	386	AF-Q59VG6-F1		Azole	2015	26017039
CA-HM-MAC2	C. albicans	Clinical isolate	ERG3	W228Stop	Stop	Q59VG6	386	AF-Q59VG6-F1		Azole	2015	26017039
CG-GRE-CAP	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Echinocandin	2015	26017039
CG-GRE-DUC	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Echinocandin	2015	26017039
CG-HM-HAB1	C. glabrata	Clinical isolate	PDR1	T370I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Structure not available	Fluconazole (>64), Voriconazole (4)	2015	26017039
CG-HM-HAB2a	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Caspofungin (2), Anidulafungin (2), Micafungin (1)	2015	26017039
CG-HM-HAB2b	C. glabrata	Clinical isolate	PDR1	T370I	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Structure not available	Fluconazole (>64), Voriconazole (8)	2015	26017039
ABR-1	C. albicans	Clinical isolate	orf19.7235	D216Y	Single substitution	A0A1D8PFX9	892	AF-A0A1D8PFX9-F1		Amphotericin B (0.462)	2015	26030729
ABR-10	C. albicans	Clinical isolate	ERG2	S97P	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (1.848)	2015	26030729
ABR-2	C. albicans	Clinical isolate	ERG2	W79X	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1	Structure not available	Amphotericin B (1.848)	2015	26030729
ABR-3	C. albicans	Clinical isolate	ERG2	G129D	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (0.924)	2015	26030729
ABR-4	C. albicans	Clinical isolate	orf19.7235	D216Y	Single substitution	A0A1D8PFX9	892	AF-A0A1D8PFX9-F1		Amphotericin B (0.462)	2015	26030729
ABR-o1	C. albicans	Clinical isolate	ERG6	D60N	Single substitution	O74198	376	AF-O74198-F1		Amphotericin B (1.848)	2015	26030729
ABR-o13	C. albicans	Clinical isolate	ERG2	I16N	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (1.848)	2015	26030729
AUR-1	C. albicans	Clinical isolate	ERG2	G183V	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (0.924)	2015	26030729
AUR-10	C. albicans	Clinical isolate	ERG2	L185X	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1	Structure not available	Amphotericin B (1.848)	2015	26030729
AUR-3	C. albicans	Clinical isolate	ERG2	L58X	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1	Mismatch residue	Amphotericin B (0.924)	2015	26030729
AUR-5	C. albicans	Clinical isolate	ERG2	G129D	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (0.924)	2015	26030729
AUR-7	C. albicans	Clinical isolate	ERG2	G129D	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (1.848)	2015	26030729
MUR-6	C. albicans	Clinical isolate	orf19.7235	D216Y	Single substitution	A0A1D8PFX9	892	AF-A0A1D8PFX9-F1		Amphotericin B (0.462)	2015	26030729
MUR-7	C. albicans	Clinical isolate	ERG2	H95P	Single substitution	A0A1D8PCB9	217	AF-A0A1D8PCB9-F1		Amphotericin B (0.924)	2015	26030729
MUR-9	C. albicans	Clinical isolate	RPP1A	D106E, D97E	Double substitution	Q9HFQ7	106	AF-Q9HFQ7-F1		Amphotericin B (0.924)	2015	26030729
MUR-N2	C. albicans	Clinical isolate	ERG6	I222V, Y366X	Double substitution	O74198	376	AF-O74198-F1	Mismatch residue	Amphotericin B (1.848)	2015	26030729
MUR-o3	C. albicans	Clinical isolate	ERG6	Y194F	Single substitution	O74198	376	AF-O74198-F1	Mismatch residue	Amphotericin B (0.924)	2015	26030729
Cp29	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64), Voriconazole (1)	2015	26169412
Cp30	C. parapsilosis	Clinical isolate	MRR1	R479K	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (128), Voriconazole (2), Itraconazole (1)	2015	26169412
Cp35	C. parapsilosis	Clinical isolate	TAC1	G650E	Single substitution	G8B9R1	980	AF-G8B9R1-F1		Fluconazole (128), Voriconazole (4)	2015	26169412
Cp36	C. parapsilosis	Clinical isolate	MRR1	I283R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64)	2015	26169412
Cp38	C. parapsilosis	Clinical isolate	TAC1	G650E	Single substitution	G8B9R1	980	AF-G8B9R1-F1		Fluconazole (256), Voriconazole (4)	2015	26169412
Cp40	C. parapsilosis	Clinical isolate	TAC1	L978W	Single substitution	G8B9R1	980	AF-G8B9R1-F1		Fluconazole (128), Voriconazole (8)	2015	26169412
JB12	C. parapsilosis	Laboratory strain	MRR1	K873N	Single substitution	A0A0K0NQY2	1128	AF-A0A0K0NQY2-F1		Fluconazole (64), Voriconazole (2)	2015	26248365
JB14	C. parapsilosis	Laboratory strain	MRR1	G583R	Single substitution	A0A0K0NQY2	1128	AF-A0A0K0NQY2-F1		Fluconazole (64), Voriconazole (2)	2015	26248365
JB4	C. parapsilosis	Laboratory strain	MRR1	K873N, Q1064P	Double substitution	A0A0K0NQY2	1128	AF-A0A0K0NQY2-F1		Fluconazole (64), Voriconazole (2)	2015	26248365
LEMI8379	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	26259795
LEMI8382	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	26259795
LEMI8383	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	26259795
LEMI8646	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8), Voriconazole (1)	2015	26259795
LEMI8650	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (8)	2015	26259795
LEMI8653	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	26259795
LEMI8655	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	26259795
LEMI8657	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	26259795
LEMI8662	C. parapsilosis	Clinical isolate	ERG11	A395T	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (16)	2015	26259795
PU123	C. parapsilosis	Clinical isolate	MRR1	L986P	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32)	2015	26282840
PU127	C. parapsilosis	Clinical isolate	MRR1	L986P	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32)	2015	26282840
BC2_11/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (0.5), Anidulafungin (0.125)	2015	26324281
BC3_14/06/13	C. krusei	Clinical isolate	FKS1	F655L	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (0.1), Anidulafungin (0.5)	2015	26324281
BC4_16/06/13	C. krusei	Clinical isolate	FKS1	S659P	Single substitution	Q4U2W2	1885	Model		Caspofungin (2), Micafungin (0.5), Anidulafungin (0.06)	2015	26324281
BC5_19/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (0.125)	2015	26324281
BC6_23/06/13	C. krusei	Clinical isolate	FKS1	F655L	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (1)	2015	26324281
BC7_26/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (2), Micafungin (1), Anidulafungin (0.125)	2015	26324281
BC8_29/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (0.25)	2015	26324281
CC1_11/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (0.5), Anidulafungin (0.125)	2015	26324281
CC2_14/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (0.125)	2015	26324281
CC3_26/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (0.125)	2015	26324281
CTC1_16/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (1), Micafungin (1), Anidulafungin (0.125)	2015	26324281
CTC2_23/06/13	C. krusei	Clinical isolate	FKS1	S659P	Single substitution	Q4U2W2	1885	Model		Caspofungin (2), Micafungin (0.5), Anidulafungin (0.06)	2015	26324281
STC_15/06/13	C. krusei	Clinical isolate	FKS1	P663Q	Single substitution	Q4U2W2	1885	Model		Caspofungin (4), Micafungin (1), Anidulafungin (0.125)	2015	26324281
UC_15/06/13	C. krusei	Clinical isolate	FKS1	F655L	Single substitution	Q4U2W2	1885	Model		Caspofungin (2), Micafungin (1), Anidulafungin (0.5)	2015	26324281
4263	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
4266	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
592	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ03	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ09	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ15	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ16	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ17	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ18	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ23	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ29	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ34	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ51	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
GZ58	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Fluconazole (>64)	2015	26349561
CA	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (>8), Micafungin (>2), Fluconazole (>256)	2015	26392494
CG1	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Caspofungin (2), Micafungin (0.25), Anidulafungin (0.5)	2015	26392494
CG2	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>8), Micafungin (4), Fluconazole (128)	2015	26392494
CG3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>8), Micafungin (8), Fluconazole (256)	2015	26392494
CG4	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (1), Fluconazole (>128)	2015	26392494
CG5	C. glabrata	Clinical isolate	FKS2	F659L	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2015	26392494
CG6	C. glabrata	Clinical isolate	FKS1	R636S	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (4)	2015	26392494
C15	C. albicans	Clinical isolate	MRR2	H358N, E439K, S466L, A468G, S469T, T470N	Multiple substitution	Q59MJ1	710	AF-Q59MJ1-F1		Fluconazole (32)	2015	26404130
C7	C. albicans	Clinical isolate	MRR2	H358N, E439K, S466L, A468G, S469T, T470N	Multiple substitution	Q59MJ1	710	AF-Q59MJ1-F1		Fluconazole (64)	2015	26404130
C9	C. albicans	Clinical isolate	MRR2	H358N, E439K, S466L, A468G, S469T, T470N	Multiple substitution	Q59MJ1	710	AF-Q59MJ1-F1		Fluconazole (128)	2015	26404130
20/10/2013	C. lusitaniae	Clinical isolate	FKS1	S638P	Single substitution	A0A202G441	1886	Model		Caspofungin (8), Micafungin (16), Anidulafungin (4)	2015	26438490
23/08/2013	C. lusitaniae	Clinical isolate	FKS1	S631Y	Single substitution	A0A202G441	1886	Model		Caspofungin (8), Micafungin (16), Anidulafungin (4)	2015	26438490
41275	C. lusitaniae	Clinical isolate	FKS1	S638Y	Single substitution	A0A202G441	1886	Model		Caspofungin (4), Micafungin (16), Anidulafungin (2), Amphotericin B (2)	2015	26438490
41315	C. lusitaniae	Clinical isolate	FKS1	S631Y	Single substitution	A0A202G441	1886	Model		Caspofungin (4), Micafungin (8), Anidulafungin (4), Fluconazole (32)	2015	26438490
n=13 isolates	C. albicans	Clinical isolate	ERG11	E116D	Single substitution	C7DRL6	528	AF-C7DRL6-F1	Structure not available	Fluconazole (>64), Itraconazole (>1)	2016	26648048
CgGermany	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (16), Micafungin (1), Fluconazole (128), Voriconazole (16)	2016	26806376
isolate 6	C. tropicalis	Clinical isolate	ERG3	378fs	Frameshift	C5MEI7	392	AF-C5MEI7-F1		Fluconazole (>64), Itraconazole (>16), Ketoconazole (16), Posaconazole (>16), Voriconazole (>16)	2016	26949597
isolate 7	C. tropicalis	Clinical isolate	ERG3	378fs	Frameshift	C5MEI7	392	AF-C5MEI7-F1		Fluconazole (>64), Itraconazole (>16), Ketoconazole (>16), Posaconazole (>16), Voriconazole (>16)	2016	26949597
isolate 8	C. tropicalis	Clinical isolate	ERG3	378fs	Frameshift	C5MEI7	392	AF-C5MEI7-F1		Fluconazole (>64), Itraconazole (>16), Ketoconazole (>16), Posaconazole (>16), Voriconazole (>16)	2016	26949597
Duke 246	C. glabrata	Clinical isolate	MSH2 PDR1	P208S, N890I G1079R	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
Duke 249	C. glabrata	Clinical isolate	FKS2 MSH2 PDR1	S663P P208S, N890I G1079R	Single substitution Double substitution Single substitution	Q6FMZ3 Q6FQA9 Q6FXU7	1897 957 1107	Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Multidrug	2016	27020939
Duke 307	C. glabrata	Clinical isolate	FKS2 MSH2	S663P E231G, L269F	Single substitution Double substitution	Q6FMZ3 Q6FQA9	1897 957	Model AF-Q6FQA9-F1		Echinocandin	2016	27020939
SK 1	C. glabrata	Clinical isolate	MSH2 PDR1	V239L L825P	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
SK 2	C. glabrata	Clinical isolate	FKS2 MSH2 PDR1	I660_L661insF V239L L825P	Insertion Single substitution Single substitution	Q6FMZ3 Q6FQA9 Q6FXU7	1897 957 1107	Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Multidrug	2016	27020939
UHL 2248	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T E1083Q	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2257	C. glabrata	Clinical isolate	MSH2 PDR1	V239L N691D	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2268	C. glabrata	Clinical isolate	MSH2 PDR1	V239S, A942T S316I	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2271	C. glabrata	Clinical isolate	MSH2 PDR1	V239L D261G	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2273	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T R293I	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2277	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T R592S	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2279	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T G583S	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 2282	C. glabrata	Clinical isolate	MSH2	V239L, A942T	Double substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole	2016	27020939
UHL 2312	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T Y584C	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
UHL 530	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T E1083Q	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 057-02	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T R792stop	Double substitution Stop	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 162-11	C. glabrata	Clinical isolate	MSH2 PDR1	E231G, L269F R295G	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 659-11	C. glabrata	Clinical isolate	MSH2 PDR1	E231G, L269F R265G	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 86-14	C. glabrata	Clinical isolate	MSH2 PDR1	E231G, L269F E340G	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 906-05	C. glabrata	Clinical isolate	MSH2 PDR1	V239L D1082G	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
WSU 961-00	C. glabrata	Clinical isolate	MSH2 PDR1	V239L, A942T R792stop	Double substitution Stop	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole	2016	27020939
patient 1	C. tropicalis	Clinical isolate	UPC2	A251T, Q289L	Double substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (32), Itraconazole (1)	2016	27044550
patient 2	C. tropicalis	Clinical isolate	UPC2	A297S, T393I, 301-304del, Q320insertPP	Complex	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (16), Voriconazole (1), Itraconazole (2)	2016	27044550
patient 4	C. tropicalis	Clinical isolate	UPC2	A251T, G392E	Double substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (8), Itraconazole (1), Posaconazole (0.25)	2016	27044550
patient 5	C. tropicalis	Clinical isolate	ERG11 UPC2	L333I G392E	Single substitution Single substitution	P14263 C5MAR7	528 782	AF-P14263-F1 AF-C5MAR7-F1		Fluconazole (4), Itraconazole (1), Posaconazole (0.25)	2016	27044550
patient 6	C. tropicalis	Clinical isolate	UPC2	A251T, Q289L, G392E	Multiple substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (4), Itraconazole (1), Posaconazole (0.5)	2016	27044550
patient 7	C. tropicalis	Clinical isolate	ERG11 UPC2	G464S A251T, Q289L	Single substitution Double substitution	P14263 C5MAR7	528 782	AF-P14263-F1 AF-C5MAR7-F1		Fluconazole (64), Voriconazole (2), Itraconazole (2), Posaconazole (1)	2016	27044550
patient 8	C. tropicalis	Clinical isolate	UPC2	A251T, Q289L, L343F	Multiple substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (16), Voriconazole (2), Itraconazole (1), Posaconazole (0.25)	2016	27044550
patient 9	C. tropicalis	Clinical isolate	UPC2	A251T, Q289L, G392E	Multiple substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (4), Posaconazole (0.25)	2016	27044550
Cg1	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (0.5)	2016	27061369
Cg2	C. glabrata	Clinical isolate	FKS2	D666E, K753Q	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2016	27061369
Cg3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (0.5)	2016	27061369
Ct1	C. tropicalis	Clinical isolate	FKS1	F641L	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (1)	2016	27061369
Ct2	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (2), Caspofungin (2), Micafungin (1)	2016	27061369
patient 1	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5-1), Micafungin (0.25), Caspofungin (0.5-1)	2016	27069849
patient 2	C. glabrata	Clinical isolate	FKS2	R1377K	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (2)	2016	27069849
CA1	C. albicans	Clinical isolate	FKS1	F641I	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.12), Anidulafungin (0.12), Caspofungin (0.5)	2016	27287236
CA2	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.25), Anidulafungin (0.12), Caspofungin (0.5)	2016	27287236
CA3	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.5), Anidulafungin (0.5), Caspofungin (2)	2016	27287236
CA4	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (1)	2016	27287236
CA5	C. albicans	Clinical isolate	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (1), Anidulafungin (2), Caspofungin (1)	2016	27287236
CA6	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.5), Anidulafungin (1), Caspofungin (1)	2016	27287236
CA7	C. albicans	Clinical isolate	FKS1	D698Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (0.5)	2016	27287236
CA8	C. albicans	Clinical isolate	FKS1	P649H	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (0.5)	2016	27287236
CA9	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (CD101) (1), Anidulafungin (1), Caspofungin (1)	2016	27287236
CG1	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Rezafungin (CD101) (1), Anidulafungin (1), Caspofungin (0.5)	2016	27287236
CG2	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Rezafungin (CD101) (2), Anidulafungin (4), Caspofungin (≥8)	2016	27287236
CG3	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Rezafungin (CD101) (0.12), Anidulafungin (0.25), Caspofungin (0.25)	2016	27287236
CG4	C. glabrata	Clinical isolate	FKS1	L630I	Single substitution	Q6FTN8	1863	Model		Rezafungin (CD101) (0.06), Anidulafungin (0.06), Caspofungin (0.25)	2016	27287236
CG5	C. glabrata	Clinical isolate	FKS2	D648E	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (0.25)	2016	27287236
CG6	C. glabrata	Clinical isolate	FKS1	F625Y	Single substitution	Q6FTN8	1863	Model		Rezafungin (CD101) (0.06), Anidulafungin (0.12), Caspofungin (0.12)	2016	27287236
CG7	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Rezafungin (CD101) (0.5), Anidulafungin (1), Caspofungin (2)	2016	27287236
CG8	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (CD101) (1), Anidulafungin (2), Caspofungin (1)	2016	27287236
CG9	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (0.5)	2016	27287236
Ck1	C. krusei	Clinical isolate	FKS1	R1361G	Single substitution	Q4U2W2	1885	Model	Mismatch residue	Rezafungin (CD101) (1), Anidulafungin (2), Caspofungin (8)	2016	27287236
Ck2	C. krusei	Clinical isolate	FKS1	F655C	Single substitution	Q4U2W2	1885	Model		Rezafungin (CD101) (0.25), Anidulafungin (0.5), Caspofungin (1)	2016	27287236
CT1	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5MF18	1280	AF-C5MF18-F1	Mismatch residue	Rezafungin (CD101) (0.5), Anidulafungin (1), Caspofungin (2)	2016	27287236
CT2	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	C5MF18	1280	AF-C5MF18-F1	Structure not available	Rezafungin (CD101) (0.25), Anidulafungin (0.25), Caspofungin (0.25)	2016	27287236
DPL18	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin	2016	27354115
DPL20	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin	2016	27354115
DPL22	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin	2016	27354115
DPL23	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Micafungin	2016	27354115
DPL30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin	2016	27354115
LIF-E10	C. albicans	Clinical isolate	ERG11	G448V, G464S	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (64), Voriconazole (1)	2016	27414653
LIF12560	C. albicans	Clinical isolate	ERG11	E116D, T128K, A298V	Multiple substitution	Q9P4W0	528	AF-Q9P4W0-F1	Structure not available	Fluconazole (8)	2016	27414653
R1	C. glabrata	Clinical isolate	ERG11	H146Q, V168F, M218K, D234E, G236V, M389V, R403G, V409L	Multiple substitution	P50859	533	5JLC		Fluconazole (>64), Voriconazole (8), Itraconazole (1)	2016	27436465
R2	C. glabrata	Clinical isolate	ERG11	I240F, K276N, K354R, M364L, V409L, E418K	Multiple substitution	P50859	533	5JLC		Fluconazole (>64), Voriconazole (8), Itraconazole (4)	2016	27436465
R3	C. glabrata	Clinical isolate	ERG11	Y252S, M267L, V407F	Multiple substitution	P50859	533	5JLC		Fluconazole (64), Voriconazole (0.5), Itraconazole (4)	2016	27436465
R4	C. glabrata	Clinical isolate	ERG11	I240F, E287D, Y405H	Multiple substitution	P50859	533	5JLC		Fluconazole (64), Voriconazole (0.5), Itraconazole (1)	2016	27436465
ISOLATE 3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Amphotericin B (1), Fluconazole (>64), Itraconazole (>16), Voriconazole (4), Posaconazole (>8), Caspofungin (>16), Micafungin (2)	2016	27484020
ISOLATE 4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Amphotericin B (1), Fluconazole (>64), Itraconazole (>16), Voriconazole (4), Posaconazole (>8), Caspofungin (>16), Micafungin (2)	2016	27484020
ISOLATE 5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Amphotericin B (1), Fluconazole (>64), Itraconazole (>16), Voriconazole (4), Posaconazole (>8), Caspofungin (>16), Micafungin (1)	2016	27484020
n=1 isolate	C. glabrata	Clinical isolate	FKS1 FKS2	D632Y F659L	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (4), Micafungin (1) Anidulafungin (1), Caspofungin (2), Micafungin (0.12)	2016	27550360
n=2 isolates	C. glabrata	Clinical isolate	FKS1 FKS1	D632E D632E	Single substitution Single substitution	Q6FTN8 Q6FTN8	1863 1863	Model Model		Anidulafungin (2), Caspofungin (2), Micafungin (2) Anidulafungin (1), Caspofungin (0.5-1), Micafungin (0.25)	2016	27550360
n=3 isolates	C. glabrata	Clinical isolate	FKS1 FKS2 FKS2 FKS2	F625S F659del F659S S663F	Single substitution Deletion Single substitution Single substitution	Q6FTN8 Q6FMZ3 Q6FMZ3 Q6FMZ3	1863 1897 1897 1897	Model Model Model Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5) Anidulafungin (2), Caspofungin (8), Micafungin (4) Anidulafungin (1-4), Caspofungin (1-32), Micafungin (0.12-4) Anidulafungin (4), Caspofungin (4), Micafungin (4)	2016	27550360
n=4 isolates	C. glabrata	Clinical isolate	FKS1 FKS2	S629P F659V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4-8), Caspofungin (8-32), Micafungin (2-8) Anidulafungin (1), Caspofungin (4), Micafungin (0.25-1)	2016	27550360
n=6 isolates	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.06-0.12), Caspofungin (0.06-0.25), Micafungin (0.03)	2016	27550360
n=8 isolates	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1-8), Caspofungin (4-32), Micafungin (0.5-32)	2016	27550360
R1	C. glabrata	Clinical isolate	PDR1	D243N, P915R	Double substitution	Q66WF3	1107	AF-Q5S636-F1		Fluconazole (>64), Voriconazole (8), Itraconazole (1)	2017	27744635
R2	C. glabrata	Clinical isolate	PDR1	W297R, P915R	Double substitution	Q66WF3	1107	AF-Q5S636-F1		Fluconazole (>64), Voriconazole (8), Itraconazole (4)	2017	27744635
R4	C. glabrata	Clinical isolate	PDR1	T588A, P915R	Double substitution	Q66WF3	1107	AF-Q5S636-F1		Fluconazole (>64), Itraconazole (2)	2017	27744635
R5	C. glabrata	Clinical isolate	PDR1	F575L, P915R	Double substitution	Q66WF3	1107	AF-Q5S636-F1		Fluconazole (>64), Itraconazole (1)	2017	27744635
R7	C. glabrata	Clinical isolate	PDR1	H576Y, P915R	Double substitution	Q66WF3	1107	AF-Q5S636-F1		Fluconazole (>64), Itraconazole (1)	2017	27744635
D113/drainage fluid	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model		Anidulafungin (0.5), Micafungin (0.5) [EUCAST] Caspofungin (1.5) [Etest]	2017	27855078
D113/mouth	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model		Anidulafungin (0.5), Micafungin (0.5) [EUCAST] Caspofungin (1) [Etest]	2017	27855078
D12/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D120/abdominal collection	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model		Anidulafungin (0.5), Micafungin (0.5) [EUCAST] Caspofungin (1) [Etest]	2017	27855078
D120/abscess	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model		Anidulafungin (0.125), Micafungin (0.5) [EUCAST] Caspofungin (3) [Etest]	2017	27855078
D127/peritoneal fluid	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model		Anidulafungin (0.125), Micafungin (0.5) [EUCAST] Caspofungin (1.5) [Etest]	2017	27855078
D19/ urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D26/anus	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125)	2017	27855078
D26/inguinal	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D26/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D32/anus	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.125), Micafungin (1)	2017	27855078
D33/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D40/anus	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D40/inguinal	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D40/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.062)	2017	27855078
D47/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Micafungin (0.062)	2017	27855078
D54/inguinal	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125)	2017	27855078
D54/urine	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Micafungin (0.062)	2017	27855078
D61/anus	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Micafungin (0.125) [EUCAST] Micafungin (0.25) [Etest]	2017	27855078
D61/urine	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.25) [EUCAST] Micafungin (0.25), Caspofungin (0.75) [Etest]	2017	27855078
D68/urine	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (0.25) [EUCAST] Micafungin (0.38), Caspofungin (0.75) [Etest]	2017	27855078
D75/anus	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.5) [EUCAST] Micafungin (0.25), Caspofungin (0.5) [Etest]	2017	27855078
D75/inguinal	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (0.5) [EUCAST] Micafungin (0.25), [Etest]	2017	27855078
D75/urine	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.25) [EUCAST] Micafungin (0.25), Caspofungin (0.5) [Etest]	2017	27855078
D82/urine	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (0.5) [EUCAST] Caspofungin (0.5) [Etest]	2017	27855078
D89/anus	C. glabrata	Clinical isolate	FKS2	F659S, S663A, D666E	Multiple substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (8) [EUCAST] Micafungin (0.25), Caspofungin (4) [Etest]	2017	27855078
D89/inguinal	C. glabrata	Clinical isolate	FKS2	F659S, S663A	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (0.5) [EUCAST] Micafungin (0.25) [Etest]	2017	27855078
CG1(Initial Micafungin conc:0.062)	C. glabrata	Clinical isolate	FKS2	S663P, D666Y	Double substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Anidulafungin (2)	2017	27872063
CG1(Initial Micafungin conc:0.125)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (2)	2017	27872063
CG1(Initial Micafungin conc:0.25)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (2)	2017	27872063
CG1(Initial Micafungin conc:0.5)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2017	27872063
CG1(Initial Micafungin conc:1)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (4)	2017	27872063
CG1(Initial Micafungin conc:2)	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (4)	2017	27872063
CG2(Initial Micafungin conc:0.125)	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.125), Anidulafungin (0.5)	2017	27872063
CG2(Initial Micafungin conc:0.25)	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.125), Anidulafungin (1)	2017	27872063
CG2(Initial Micafungin conc:0.5)	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Anidulafungin (2)	2017	27872063
CG2(Initial Micafungin conc:1)	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5), Anidulafungin (2)	2017	27872063
CG2(Initial Micafungin conc:2)	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (2)	2017	27872063
CG3(Initial Micafungin conc:0.25)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2017	27872063
CG3(Initial Micafungin conc:0.5)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1)	2017	27872063
CG3(Initial Micafungin conc:1)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1)	2017	27872063
CG3(Initial Micafungin conc:2)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (0.062), Anidulafungin (1)	2017	27872063
CG4(initial Micafungin conc. 0.125,0.25,0.5,1,2	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2017	27872063
CG5(Initial Micafungin conc:0.125)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2017	27872063
CG5(Initial Micafungin conc:0.25)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2017	27872063
CG5(Initial Micafungin conc:0.5)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2017	27872063
CG5(Initial Micafungin conc:1)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (4)	2017	27872063
CG5(Initial Micafungin conc:2)	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (4)	2017	27872063
CA17	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA22	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA312	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA36	C. albicans	Clinical isolate	ERG11	V234F	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA37	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA39	C. albicans	Clinical isolate	ERG11	D117E	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1	Mismatch residue	5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA42	C. albicans	Clinical isolate	ERG11	E174A	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1		5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CA43	C. albicans	Clinical isolate	ERG11	E165K	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1	Mismatch residue	5-Flucytosine (>32), Fluconazole (>64), Itraconazole (>1), Voriconazole (>4)	2017	27976986
CNRMA13.694	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (4), Micafungin (0.5), Anidulafungin (0.5)	2016	27995055
CNRMA13.695	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (2), Anidulafungin (0.25)	2016	27995055
CNRMA13.778	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (4), Micafungin (0.5), Anidulafungin (0.5)	2016	27995055
CNRMA13.779	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Micafungin (1), Anidulafungin (0.25)	2016	27995055
Cg1A	C. glabrata	Clinical isolate	MSH2 PDR1	P208S, N890I G1079R	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128.1)	2016	28018323
Cg1B	C. glabrata	Clinical isolate	FKS2 MSH2 PDR1	S663P P208S, N890I G1079R	Single substitution Double substitution Single substitution	Q6FMZ3 Q6FQA9 Q6FXU7	1897 957 1107	Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128.1), Anidulafungin (4), Micafungin (8.1), Caspofungin (8.1)	2016	28018323
Cg2A	C. glabrata	Clinical isolate	MSH2	E231G, L269F	Double substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole (16)	2016	28018323
Cg2B	C. glabrata	Clinical isolate	FKS2 MSH2	S663P E231G, L269F	Single substitution Double substitution	Q6FMZ3 Q6FQA9	1897 957	Model AF-Q6FQA9-F1		Anidulafungin (1), Caspofungin (2), Micafungin (0.5)	2016	28018323
Cg3B	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2016	28018323
124i	C. krusei	Clinical isolate	FKS1	L701M	Single substitution	Q4U2W2	1885	Model		Anidulafungin (0.125), Caspofungin (1)	2017	28065893
217i	C. albicans	Clinical isolate	ERG11	K128T, T220L	Double substitution	P10613	528	5V5Z	Mismatch residue	Itraconazole (0.125)	2017	28065893
24i	C. tropicalis	Clinical isolate	ERG11	K143X	Single substitution	C5MGS9	528	AF-C5MGS9-F1	Structure not available	Itraconazole (>8), Voriconazole (4), Posaconazole (4), Fluconazole (64)	2017	28065893
403i	C. tropicalis	Clinical isolate	ERG11	K143R	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Itraconazole (1), Voriconazole (8), Posaconazole (1), Fluconazole (>64)	2017	28065893
541i	C. albicans	Clinical isolate	ERG11	T220L	Single substitution	P10613	528	5V5Z	Mismatch residue	Voriconazole (1)	2017	28065893
ISOLATE 230	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (0.25)	2016	28066361
ISOLATE 96	C. glabrata	Clinical isolate	FKS1 MSH2	K1323T P208S, N890I	Single substitution Double substitution	Q6FTN8 Q6FQA9	1863 957	Model AF-Q6FQA9-F1		Fluconazole (64), Micafungin (0.03)	2016	28066361
BC014Rpsc	C. parapsilosis	Clinical isolate	ERG3	R135I	Single substitution	G8B7T4	405	AF-G8B7T4-F1		Fluconazole (>64), Voriconazole (>8), Posaconazole (>16)	2017	28196695
Ca	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (4), Anidulafungin (0.25), Micafungin (2)	2017	28293420
Ct	C. tropicalis	Clinical isolate	FKS1	S80P	Single substitution	C5MF18	1280	AF-C5MF18-F1	Mismatch residue	Caspofungin (2), Anidulafungin (0.5), Micafungin (1)	2017	28293420
CMRL-10	C. glabrata	Clinical isolate	CDR1 ERG9 SNQ2	H58Y C128F Y777C	Single substitution Single substitution Single substitution	Q6FK23 Q9HGZ6 Q6FQN3	1499 443 1507	AF-Q6FK23-F1 AF-Q9HGZ6-F1 AF-Q6FQN3-F1		Voriconazole (0.5)	2017	28344162
CMRL-12	C. glabrata	Clinical isolate	CDR1 FLR1 PDR1	H58Y V254I N768D	Single substitution Single substitution Single substitution	Q6FK23 Q6FRT6 Q6FXU7	1499 557 1107	AF-Q6FK23-F1 AF-Q6FRT6-F1 AF-Q6FXU7-F1		Posaconazole (>8), Voriconazole (2), Itraconazole (8), Fluconazole (128)	2017	28344162
CMRL-2	C. glabrata	Clinical isolate	FKS1 FLR1 SNQ2	S629P I116V G1421S	Single substitution Single substitution Single substitution	Q6FTN8 Q6FRT6 Q6FQN3	1863 557 1507	Model AF-Q6FRT6-F1 AF-Q6FQN3-F1		Anidulafungin (1), Micafungin (1), Caspofungin (8),	2017	28344162
CMRL-4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Amphotericin B (2), Anidulafungin (1), Micafungin (1), Caspofungin (>8)	2017	28344162
CMRL-5	C. glabrata	Clinical isolate	CDR1 ERG9	H58Y C128F	Single substitution Single substitution	Q6FK23 Q9HGZ6	1499 443	AF-Q6FK23-F1 AF-Q9HGZ6-F1		Voriconazole (0.5)	2017	28344162
CMRL-6	C. glabrata	Clinical isolate	CDR1 ERG9 FCY2 PDR1	H58Y C128F A237T R376Q	Single substitution Single substitution Single substitution Single substitution	Q6FK23 Q9HGZ6 Q6FLU1 Q6FXU7	1499 443 543 1107	AF-Q6FK23-F1 AF-Q9HGZ6-F1 AF-Q6FLU1-F1 AF-Q6FXU7-F1		5-Flucytosine (>64), Posaconazole (>8), Voriconazole (8), Itraconazole (>16), Fluconazole (256)	2017	28344162
CMRL-7	C. glabrata	Clinical isolate	CDR1 FLR1 PDR1	M638I, N1108S I116V, M103I R250K, G943D	Double substitution Double substitution Double substitution	Q6FK23 Q6FRT6 Q6FXU7	1499 557 1107	AF-Q6FK23-F1 AF-Q6FRT6-F1 AF-Q6FXU7-F1		Voriconazole (8), Fluconazole (256), Caspofungin (0.25)	2017	28344162
CMRL-9	C. glabrata	Clinical isolate	ERG9 FLR1 PDR1	C344Y I116V, M103I D243N	Single substitution Double substitution Single substitution	Q9HGZ6 Q6FRT6 Q6FXU7	443 557 1107	AF-Q9HGZ6-F1 AF-Q6FRT6-F1 AF-Q6FXU7-F1		Voriconazole (0.5)	2017	28344162
Kw2006-15	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Multiple substitution	C7EXA5	522	AF-C7EXA5-F1	Structure not available	Etest[Fluconazole (>256), Voriconazole (>32)], Vitek II[Fluconazole (32), Voriconazole (2)]	2017	28353392
Kw2097-14	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Multiple substitution	C7EXA5	522	AF-C7EXA5-F1	Structure not available	Etest[Fluconazole (24)], Vitek II[Fluconazole (64), Voriconazole (1)]	2017	28353392
Kw210-12	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Multiple substitution	C7EXA5	522	AF-C7EXA5-F1	Structure not available	Etest[Fluconazole (16), Voriconazole (2)], Vitek II[Fluconazole (16), Voriconazole (1)]	2017	28353392
Kw3816-15	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Multiple substitution	C7EXA5	522	AF-C7EXA5-F1	Structure not available	Etest[Fluconazole (>256), Voriconazole (2)]Vitek II[Fluconazole (32), Voriconazole (1)]	2017	28353392
Kw576-15	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Multiple substitution	C7EXA5	522	AF-C7EXA5-F1	Structure not available	Etest[Fluconazole (12), Voriconazole (1)], Vitek II[Fluconazole (16), Voriconazole (1), Caspofungin (1)]	2017	28353392
1587	C. albicans	Clinical isolate	MRR1	N803D	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (4)	2017	28461316
2271	C. albicans	Clinical isolate	MRR1	Q350L	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (16)	2017	28461316
6692	C. albicans	Clinical isolate	MRR1	K335N, T360I	Double substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (64)	2017	28461316
B4	C. albicans	Clinical isolate	MRR1	G878E	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (32)	2017	28461316
DSY2286	C. albicans	Clinical isolate	MRR1	T896I	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (16)	2017	28461316
DSY296	C. albicans	Clinical isolate	TAC1	N977D	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (128)	2017	28461316
F5	C. albicans	Clinical isolate	MRR1 UPC2	P683S G648S	Single substitution Single substitution	Q5A4G2 Q59QC7	1108 712	AF-Q5A4G2-F1 AF-Q59QC7-F1		Fluconazole (128)	2017	28461316
G5	C. albicans	Clinical isolate	MRR1	G997V	Single substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Fluconazole (128)	2017	28461316
Gu5	C. albicans	Clinical isolate	TAC1	G980E	Single substitution	A0A1D8PN96	981	AF-A0A1D8PN96-F1		Fluconazole (>256)	2017	28461316
TW17	C. albicans	Clinical isolate	MRR1 TAC1 UPC2	G947S A736V, 962-969Del A643V	Single substitution Complex Single substitution	Q5A4G2 A0A1D8PN96 Q59QC7	1108 981 712	AF-Q5A4G2-F1 AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>256)	2017	28461316
CG 849W	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.38)	2017	28491490
CG 864P	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (>32), Micafungin (1.5), Anidulafungin (1)	2017	28491490
Ct	C. tropicalis	Clinical isolate	ERG11	Y132C, S154C	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256), Itraconazole (4), Voriconazole (16), Posaconazole (2)	2017	28507109
CA1	C. albicans	Clinical isolate	FKS1	F641I	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Ibrexafungerp (SCY-078) (2)	2017	28533234
CA2	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Structure not available	Ibrexafungerp (SCY-078) (2), Caspofungin (1)	2017	28533234
CA3	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Ibrexafungerp (SCY-078) (0.5), Anidulafungin (1), Caspofungin (2), Micafungin (2)	2017	28533234
CA4	C. albicans	Clinical isolate	FKS1	L701M	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Anidulafungin (1), Caspofungin (2), Micafungin (2)	2017	28533234
CA5	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (2)	2017	28533234
CD	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	D3IZZ7	1897	Model	Structure not available	Anidulafungin (0.5), Caspofungin (2), Micafungin (1)	2017	28533234
CG1	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (16), Anidulafungin (4), Caspofungin (16), Micafungin (2)	2017	28533234
CG10	C. glabrata	Clinical isolate	FKS2	D648E	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (0.5)	2017	28533234
CG11	C. glabrata	Clinical isolate	FKS1	S645P	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (2), Caspofungin (2), Micafungin (1)	2017	28533234
CG12	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2017	28533234
CG13	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25)	2017	28533234
CG14	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2017	28533234
CG15	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (8), Micafungin (2)	2017	28533234
CG16	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (8), Micafungin (2)	2017	28533234
CG17	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (4)	2017	28533234
CG18	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5)	2017	28533234
CG19	C. glabrata	Clinical isolate	FKS2	D666E, K753Q	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.5)	2017	28533234
CG2	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Q6FTN8	1863	Model		Ibrexafungerp (SCY-078) (4), Anidulafungin (2), Caspofungin (1)	2017	28533234
CG20	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25)	2017	28533234
CG3	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (4), Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2017	28533234
CG4	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (4), Anidulafungin (4), Caspofungin (2), Micafungin (1)	2017	28533234
CG5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (4), Anidulafungin (4), Caspofungin (2), Micafungin (1)	2017	28533234
CG6	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (4), Anidulafungin (4), Caspofungin (4), Micafungin (2)	2017	28533234
CG7	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Anidulafungin (1), Caspofungin (0.5)	2017	28533234
CG8	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2017	28533234
CG9	C. glabrata	Clinical isolate	FKS1	R631S, S629P	Double substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.5)	2017	28533234
CKF	C. kefyr	Clinical isolate	FKS1	R1344S	Single substitution	W0TDH9	1892	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (0.06), Micafungin (0.25)	2017	28533234
CKU	C. krusei	Clinical isolate	FKS1	L701M	Single substitution	Q4U2W2	1885	Model		Caspofungin (1)	2017	28533234
CT	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	B6S6L8	1904	Model	Mismatch residue	Ibrexafungerp (SCY-078) (2), Anidulafungin (2), Caspofungin (2), Micafungin (2)	2017	28533234
BAD144-27	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2.52), Micafungin (1.26)	2017	28630180
BAD144-4	C. glabrata	Clinical isolate	FKS1	F625L	Single substitution	Q6FTN8	1863	Model		Ibrexafungerp (SCY-078) (0.79), Micafungin (0.08)	2017	28630180
BAD144-9	C. glabrata	Clinical isolate	FKS2	F659L, I661F	Double substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (1.59), Micafungin (0.4)	2017	28630180
BAD40-15	C. glabrata	Clinical isolate	FKS1	F625del	Deletion	Q6FTN8	1863	Model		Ibrexafungerp (SCY-078) (1.26), Micafungin (0.06)	2017	28630180
BAD40-18	C. glabrata	Clinical isolate	FKS2	E655A	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2.52), Micafungin (0.2)	2017	28630180
BAD40-2	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2.52), Micafungin (2.52)	2017	28630180
BAD40-20	C. glabrata	Clinical isolate	FKS2	F659L	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (3.17), Micafungin (0.08)	2017	28630180
BAD40-31	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Micafungin (0.79)	2017	28630180
BAD40-36	C. glabrata	Clinical isolate	FKS2	W715L	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (4), Micafungin (0.31)	2017	28630180
BAD40-9	C. glabrata	Clinical isolate	FKS2	A1390D	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (8), Micafungin (0.12)	2017	28630180
BAD47-14	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Micafungin (0.5)	2017	28630180
BAD47-3	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (3.17), Micafungin (0.25)	2017	28630180
BAD47-5	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Micafungin (0.79)	2017	28630180
BAD47-6	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Micafungin (0.79)	2017	28630180
BAD47-9	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Ibrexafungerp (SCY-078) (2), Micafungin (1)	2017	28630180
35176 (isolate 2)	C. parapsilosis	Clinical isolate	ERG3	G111R	Single substitution	A0A1L2BH72	405	AF-A0A1L2BH72-F1	Mismatch residue	Fluconazole (>64), Voriconazole (>160, Itraconazole (>16), Posaconazole (>16), Anidulafungin (4), Caspofungin (>16), Micafungin (>16)	2017	28630186
DSY565	C. glabrata	Clinical isolate	PDR1	L280F	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (64), Voriconazole (1)	2017	28663342
California 1	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (8), Micafungin (2)	2017	28784671
California 2	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25), Caspofungin (0.5)	2017	28784671
California 3	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2017	28784671
Canada	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2017	28784671
Georgia	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2017	28784671
Indiana 1	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1), Micafungin (1)	2017	28784671
Indiana 2	C. glabrata	Clinical isolate	FKS1 FKS2	F625S F659Y	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2017	28784671
Israel	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (2)	2017	28784671
New York 1	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1), Micafungin (1)	2017	28784671
New York 2	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2017	28784671
New York 3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.25)	2017	28784671
New York 4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (2)	2017	28784671
ATCC 90028mtS645Y	C. albicans	Laboratory strain	FKS1	S645Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Micafungin (1)	2017	28827418
CA 46503mtS645P	C. albicans	Laboratory strain	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Micafungin (1)	2017	28827418
n=1 ISOLATES	C. glabrata	Clinical isolate	FKS2	D666G	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2017	28831086
n=2 ISOLATES	C. glabrata	Clinical isolate	FKS1 FKS1 FKS1	D632E F625S S629P	Single substitution Single substitution Single substitution	Q6FTN8 Q6FTN8 Q6FTN8	1863 1863 1863	Model Model Model		Anidulafungin (1) Anidulafungin (1-2) Anidulafungin (2-4)	2017	28831086
n=3 ISOLATES	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1-4)	2017	28831086
Ca	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Fluconazole (16), Voriconazole (1), Micafungin (2), Caspofungin (≥4)	2017	28841000
Ca-SC5314-R	C. lusitaniae	Laboratory strain	ERG11	K143E	Single substitution	C4Y9P2	525	AF-C4Y9P2-F1		Fluconazole (8)	2018	29038279
Cl-6936/01	C. lusitaniae	Laboratory strain	ERG11	K143E	Single substitution	C4Y9P2	525	AF-C4Y9P2-F1		Fluconazole (8)	2018	29038279
Cl-6936/02	C. lusitaniae	Laboratory strain	ERG11	E115Q, K143E	Double substitution	C4Y9P2	525	AF-C4Y9P2-F1		Fluconazole (16)	2018	29038279
FFUL887	C. glabrata	Clinical isolate	CAGL0L04400g CAGL0L09383g GAL11A GAL11B HST1 PDH1 PDR1 SIN3 UPC2A	C24G, A58V, I137L, D229E, I346V, E574K, I593L, E710D, A933V S116N, I185V, M202V S134N, S965G, S1084N Q203P, H322N, P372S, I615N, 839Ginsertion M70K K438Q, E839D L98S, D243N, K274Q N50K, K288T R92K, N304S, E822V	Multiple substitution Multiple substitution Multiple substitution Complex Single substitution Double substitution Multiple substitution Double substitution Multiple substitution	Q6FLC8 Q6FKR1 Q6FRS9 Q6FUT5 Q6FWI7 O74208 Q6FXU7 Q6FVE7 Q6FX18	987 366 1095 838 509 1542 1107 1493 922	AF-Q6FLC8-F1 AF-Q6FKR1-F1 AF-Q6FRS9-F1 AF-Q6FUT5-F1 AF-Q6FWI7-F1 AF-O74208-F1 AF-Q6FXU7-F1 Model AF-Q6FX18-F1		Fluconazole, Voriconazole	2018	29087506
C1	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C108	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (64)	2018	29136186
C121	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (32), Fluconazole (128)	2018	29136186
C14	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (128)	2018	29136186
C17	C. albicans	Clinical isolate	ERG11	A114S, G465S	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Fluconazole (64)	2018	29136186
C2	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C20	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C21	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Fluconazole (64)	2018	29136186
C22	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Fluconazole (64)	2018	29136186
C23	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Fluconazole (128)	2018	29136186
C25	C. albicans	Clinical isolate	ERG11	A114S	Single substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (2), Fluconazole (128)	2018	29136186
C26	C. albicans	Clinical isolate	ERG11	K128T, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C3	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C6	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (128)	2018	29136186
C7	C. albicans	Clinical isolate	ERG11	A114S	Single substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
C9	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (64)	2018	29136186
R183	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
R21	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (8), Voriconazole (16), Fluconazole (128)	2018	29136186
R255	C. albicans	Clinical isolate	ERG11 ERG3	T123I, Y132H A18P	Double substitution Single substitution	P10613 Q59VG6	528 386	5V5Z AF-Q59VG6-F1		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
R410	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (4), Fluconazole (64)	2018	29136186
R415	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
R44	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (8), Voriconazole (2), Fluconazole (64)	2018	29136186
R517	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (64)	2018	29136186
R654	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (128)	2018	29136186
R901	C. albicans	Clinical isolate	ERG11	P98S, T123I, Y132H	Multiple substitution	P10613	528	5V5Z		Itraconazole (8), Voriconazole (8), Fluconazole (64)	2018	29136186
S1007	C. albicans	Clinical isolate	ERG11 ERG3	Y132H, Y286D, G448E R365G	Multiple substitution Single substitution	P10613 Q59VG6	528 386	5V5Z AF-Q59VG6-F1		Itraconazole (16), Voriconazole (8), Fluconazole (128)	2018	29136186
S20	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (8), Voriconazole (8), Fluconazole (64)	2018	29136186
S201	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	P10613	528	5V5Z		Itraconazole (4), Voriconazole (2), Fluconazole (64)	2018	29136186
S202	C. albicans	Clinical isolate	ERG11	Y132H, G448E	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (8), Fluconazole (128)	2018	29136186
S27	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Itraconazole (16), Voriconazole (16), Fluconazole (128)	2018	29136186
CG1	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29228268
CG2	C. glabrata	Clinical isolate	FKS2	W715L	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29228268
CG3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (4)	2018	29228268
CG4	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (1)	2018	29228268
CG5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29228268
ISOLATE 1-Micafungin	C. glabrata	Clinical isolate	FKS2 FKS2	E655A F658del	Single substitution Deletion	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (0.25), Anidulafungin (0.5) Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 10-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (2)	2018	29311063
ISOLATE 11-Anidulafungin	C. glabrata	Clinical isolate	FKS2 FKS2	S663P S663P	Single substitution Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (2), Anidulafungin (2) Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 12-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 12-Micafungin	C. glabrata	Clinical isolate	FKS2 FKS2	F658del W715L	Deletion Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (2), Anidulafungin (4) Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 2-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29311063
ISOLATE 2-Micafungin	C. glabrata	Clinical isolate	FKS2 FKS2	F658del W715L	Deletion Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (2), Anidulafungin (1) Micafungin (0.5), Anidulafungin (0.5)	2018	29311063
ISOLATE 3-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (4)	2018	29311063
ISOLATE 3-Micafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (4)	2018	29311063
ISOLATE 4-Micafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 5-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (1)	2018	29311063
ISOLATE 6-Micafungin	C. glabrata	Clinical isolate	FKS2 FKS2	F658del S663P	Deletion Single substitution	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (4), Anidulafungin (2)	2018	29311063
ISOLATE 7-Micafungin	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Anidulafungin (1)	2018	29311063
ISOLATE 8-Anidulafungin	C. glabrata	Clinical isolate	FKS2 FKS2	F658del F658del	Deletion Deletion	Q6FMZ3 Q6FMZ3	1897 1897	Model Model		Micafungin (4), Anidulafungin (2) Micafungin (2), Anidulafungin (2)	2018	29311063
ISOLATE 9-Anidulafungin	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Micafungin (1), Anidulafungin (2)	2018	29311063
VPCI 1/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (>64), Voriconazole (16)	2018	29325167
VPCI 10/15	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 11/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 12/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (16), Isavuconazole (4), Fluconazole (32)	2018	29325167
VPCI 13/13	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 14/13	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 15/13	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 16/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 17/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (16), Isavuconazole (4), Fluconazole (64)	2018	29325167
VPCI 18/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Voriconazole (16), Fluconazole (>64)	2018	29325167
VPCI 19/15	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 2/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (>64), Voriconazole (16), Isavuconazole (4), Posaconazole (4)	2018	29325167
VPCI 20/16	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Voriconazole (4), Fluconazole (64)	2018	29325167
VPCI 21/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 22/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (>64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 23/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (>64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 24/15	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (>64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 25/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 26/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (>64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 27/15	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (32), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 28/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 29/12	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 3/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (64)	2018	29325167
VPCI 30/12	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (32), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 31/13	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 32/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 33/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 34/14	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1		Fluconazole (64), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 35/12	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Fluconazole (8), Voriconazole (4), Isavuconazole (4), Posaconazole (8)	2018	29325167
VPCI 4/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (8), Fluconazole (>64)	2018	29325167
VPCI 45/13	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (16), Micafungin (16), Anidulafungin (8), Fluconazole (64)	2018	29325167
VPCI 46/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (8), Micafungin (16), Anidulafungin (8), Fluconazole (64)	2018	29325167
VPCI 47/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (8), Micafungin (16), Anidulafungin (8), Fluconazole (64)	2018	29325167
VPCI 48/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (4), Micafungin (16), Anidulafungin (8), Fluconazole (64)	2018	29325167
VPCI 5/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 6/14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (64)	2018	29325167
VPCI 7/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (>64)	2018	29325167
VPCI 8/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (32)	2018	29325167
VPCI 9/15	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A0L0NU49	524	AF-A0A0L0NU49-F1	Mismatch residue	Voriconazole (4), Fluconazole (64)	2018	29325167
CMRL-12	C. glabrata	Clinical isolate	PDR1 CDR1 FLR1	N768D H58Y V254I	Single substitution Single substitution Single substitution	Q6FXU7 Q6FK23 Q6FRT6	1107 1499 557	AF-Q6FXU7-F1 AF-Q6FK23-F1 AF-Q6FRT6-F1		Fluconazole (128), Itraconazole (8), Voriconazole (2), Posaconazole (>8)	2017	29364212
CMRL-2	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Micafungin (1), Caspofungin (8)	2017	29364212
CMRL-4	C. glabrata	Clinical isolate	FKS2	S633P	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (1), Micafungin (1), Caspofungin (>8)	2017	29364212
CMRL-6-1	C. glabrata	Clinical isolate	FCY2	A237T	Single substitution	Q6FPL2	515	AF-Q6FPL2-F1		5-Flucytosine (>64)	2017	29364212
CMRL-6-2	C. glabrata	Clinical isolate	ERG9	C128F	Single substitution	Q9HGZ6	443	AF-Q9HGZ6-F1		5-Flucytosine (>64), Posaconazole (>8), Voriconazole (8), Itraconazole (>16), Fluconazole (256)	2017	29364212
CMRL-6-3	C. glabrata	Clinical isolate	PDR1	R376Q	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		5-Flucytosine (>64), Posaconazole (>8), Voriconazole (8), Itraconazole (>16), Fluconazole (256)	2017	29364212
CMRL-6-4	C. glabrata	Clinical isolate	CDR1	H58Y	Single substitution	Q6FK23	1499	AF-Q6FK23-F1		Fluconazole (256), Itraconazole (>16), Voriconazole (8), Posaconazole (>8)	2017	29364212
CMRL-7-1	C. glabrata	Clinical isolate	PDR1	G250N	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Mismatch residue	Fluconazole (256), Itraconazole (0.5), Voriconazole (8), Posaconazole (1)	2017	29364212
CMRL-7-2	C. glabrata	Clinical isolate	CDR1	M638I	Single substitution	Q6FK23	1499	AF-Q6FK23-F1		Fluconazole (256), Itraconazole (0.5), Voriconazole (8), Posaconazole (1)	2017	29364212
CMRL-7-3	C. glabrata	Clinical isolate	CDR1	N1108S	Single substitution	Q6FK23	1499	AF-Q6FK23-F1		Fluconazole (256), Itraconazole (0.5), Voriconazole (8), Posaconazole (1)	2017	29364212
CMRL-7-4	C. glabrata	Clinical isolate	FLR1	I116V	Single substitution	Q6FRT6	557	AF-Q6FRT6-F1		Fluconazole (256), Itraconazole (0.5), Voriconazole (8), Posaconazole (1)	2017	29364212
CA10	C. albicans	Clinical isolate	CAP1 MRR1	A390T T917M, T923I, E1020Q, F1032L, S1037L	Single substitution Multiple substitution	O94118 Q5A4G2	499 1108	AF-O94118-F1 AF-Q5A4G2-F1		Fluconazole (>=32), Itraconazole (>=1), Voriconazole (>=4)	2017	29434708
CA14	C. albicans	Clinical isolate	CAP1	S381N	Single substitution	O94118	499	AF-O94118-F1		Fluconazole (>=32)	2017	29434708
CA42	C. albicans	Clinical isolate	MRR1	N937K, E1020Q, F1032L, S1037L	Multiple substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Voriconazole (>=4)	2017	29434708
CA50	C. albicans	Clinical isolate	MRR1	T917M, T923I, E1020Q	Multiple substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Itraconazole (>=1)	2017	29434708
CA51	C. albicans	Clinical isolate	CAP1 MRR1	P311S N937K, E1020Q	Single substitution Double substitution	O94118 Q5A4G2	499 1108	AF-O94118-F1 AF-Q5A4G2-F1		Itraconazole (>=1)	2017	29434708
CA52	C. albicans	Clinical isolate	CAP1	P311S	Single substitution	O94118	499	AF-O94118-F1		Itraconazole (>=1)	2017	29434708
CA53	C. albicans	Clinical isolate	CAP1 MRR1	P311S N937K, E1020Q, F1032L, S1037L	Single substitution Multiple substitution	O94118 Q5A4G2	499 1108	AF-O94118-F1 AF-Q5A4G2-F1		Itraconazole (>=1), Voriconazole (>=4)	2017	29434708
CA62	C. albicans	Clinical isolate	MRR1	T923I, E1020Q	Double substitution	Q5A4G2	1108	AF-Q5A4G2-F1		Itraconazole (>=1)	2017	29434708
CA63	C. albicans	Clinical isolate	CAP1 MRR1	P311S N937K, E1020Q, F1032L, S1037L	Single substitution Multiple substitution	O94118 Q5A4G2	499 1108	AF-O94118-F1 AF-Q5A4G2-F1		Itraconazole (>=1)	2017	29434708
CA67	C. albicans	Clinical isolate	CAP1	G481E	Single substitution	O94118	499	AF-O94118-F1		Voriconazole (>=4)	2017	29434708
Kw107/17	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (32), Anidulafungin (0.5), Micafungin (0.75) [Etest] Caspofungin (32), Anidulafungin (1), Micafungin (1) [CLSI]	2018	29437623
Kw3707/16	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Caspofungin (24), Anidulafungin (0.5), Micafungin (0.5) [Etest] Caspofungin (16), Anidulafungin (1), Micafungin (1) [CLSI]	2018	29437623
WT10	C. glabrata	Clinical isolate	PDR1	P927S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (2)	2018	29464833
WT2	C. glabrata	Clinical isolate	PDR1	G1099D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1)	2018	29464833
WT6	C. glabrata	Clinical isolate	PDR1	G346D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole (1), Voriconazole (4)	2018	29464833
WT8	C. glabrata	Clinical isolate	PDR1	L344S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2018	29464833
n=1 ISOLATES	C. glabrata	Clinical isolate	MSH2	V239L, D946E	Double substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
n=2 ISOLATES	C. glabrata	Clinical isolate	MSH2	T772S	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
n=34 ISOLATES	C. glabrata	Clinical isolate	MSH2	V239L	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
n=5 ISOLATES	C. glabrata	Clinical isolate	MSH2	Q386K	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
n=6 ISOLATES	C. glabrata	Clinical isolate	MSH2	R847C	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
n=9 ISOLATES	C. glabrata	Clinical isolate	MSH2	E459K	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Caspofungin (>0.5), Micafungin (>0.25), Anidulafungin (>0.5)	2018	29610199
Ct01R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (128), Voriconazole (4)	2018	29631565
Ct03R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (256), Voriconazole (4)	2018	29631565
Ct04R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Voriconazole (2)	2018	29631565
Ct05R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (128), Voriconazole (4)	2018	29631565
Ct06R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (128), Voriconazole (4)	2018	29631565
Ct07R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (256), Voriconazole (>8), Itraconazole (1), Posaconazole (1)	2018	29631565
Ct08R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Voriconazole (4), Posaconazole (1)	2018	29631565
Ct09R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (256), Voriconazole (>8), Itraconazole (1), Posaconazole (1)	2018	29631565
Ct10R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (256), Voriconazole (>8), Itraconazole (1), Posaconazole (1)	2018	29631565
Ct11R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Voriconazole (2)	2018	29631565
Ct12R	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Voriconazole (4)	2018	29631565
VPCI 1133/P/13-R	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (>16), Caspofungin (>16), Micafungin (>16)	2018	29632013
VPCI 265/P/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (16), Caspofungin (>16), Micafungin (>16)	2018	29632013
VPCI 462/P/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (>16), Caspofungin (>16), Micafungin (>16)	2018	29632013
VPCI 471a/P/14-R	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (16), Caspofungin (16), Micafungin (>16)	2018	29632013
Co289	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (4), Posaconazole (0.125), Voriconazole (0.125), Itraconazole (0.5)	2018	29635519
Co681	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (64), Posaconazole (0.125), Voriconazole (2), Itraconazole (0.5)	2018	29635519
Co687	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (64), Posaconazole (0.25), Voriconazole (2), Itraconazole (0.25)	2018	29635519
Rome22	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (128), Posaconazole (0.5), Voriconazole (4), Itraconazole (0.5)	2018	29635519
Rome23	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (64), Posaconazole (0.125), Voriconazole (2), Itraconazole (0.25)	2018	29635519
Rome24	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (128), Posaconazole (0.125), Voriconazole (4), Itraconazole (0.125)	2018	29635519
Rome25	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (128), Posaconazole (0.25), Voriconazole (2), Itraconazole (0.25)	2018	29635519
Rome26	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (128), Posaconazole (0.125), Voriconazole (4), Itraconazole (0.5)	2018	29635519
Rome27	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (64), Posaconazole (0.125), Voriconazole (4), Itraconazole (0.25)	2018	29635519
Rome28	C. orthopsilosis	Clinical isolate	ERG11	Y132F	Single substitution	H8X874	522	AF-H8X874-F1		Fluconazole (64), Posaconazole (0.25), Voriconazole (8), Itraconazole (0.25)	2018	29635519
Wild 6	C. glabrata	Clinical isolate	PDR1	G1037A	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Mismatch residue	Fluconazole (64), Voriconazole (4), Itraconazole (1)	2018	29648590
Ca	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin (1), Anidulafungin (0.25)	2018	29712651
Cg1	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (1), Anidulafungin (0.5)	2018	29712651
Cg10	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (1), Anidulafungin (2)	2018	29712651
Cg11	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (1), Anidulafungin (2)	2018	29712651
Cg12	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (1), Anidulafungin (1)	2018	29712651
Cg13	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (2)	2018	29712651
Cg14	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (2), Anidulafungin (4)	2018	29712651
Cg15	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (2), Anidulafungin (1)	2018	29712651
Cg16	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29712651
Cg17	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (4), Anidulafungin (4)	2018	29712651
Cg18	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29712651
Cg19	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29712651
Cg2	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (0.064), Anidulafungin (1)	2018	29712651
Cg20	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (2), Anidulafungin (1)	2018	29712651
Cg21	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29712651
Cg22	C. glabrata	Clinical isolate	FKS2	W715L	Single substitution	E2GKZ6	1897	Model		Micafungin (2), Anidulafungin (2)	2018	29712651
Cg23	C. glabrata	Clinical isolate	FKS2	W715L	Single substitution	E2GKZ6	1897	Model		Micafungin (0.5), Anidulafungin (0.5)	2018	29712651
Cg24	C. glabrata	Clinical isolate	FKS2	W715L	Single substitution	E2GKZ6	1897	Model		Micafungin (4), Anidulafungin (2)	2018	29712651
Cg25	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	E2GKZ6	1897	Model		Micafungin (0.064), Anidulafungin (0.25)	2018	29712651
Cg26	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	E2GKZ6	1897	Model		Micafungin (0.064), Anidulafungin (0.5)	2018	29712651
Cg27	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	E2GKZ6	1897	Model		Micafungin (1), Anidulafungin (2)	2018	29712651
Cg28	C. glabrata	Clinical isolate	FKS2	E655A	Single substitution	E2GKZ6	1897	Model		Micafungin (0.25), Anidulafungin (0.5)	2018	29712651
Cg3	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (4)	2018	29712651
Cg4	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (2), Anidulafungin (1)	2018	29712651
Cg5	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (2)	2018	29712651
Cg6	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (2), Anidulafungin (1)	2018	29712651
Cg7	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (4)	2018	29712651
Cg8	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (2)	2018	29712651
Cg9	C. glabrata	Clinical isolate	FKS2	659del	Deletion	E2GKZ6	1897	Model	Mismatch residue	Micafungin (4), Anidulafungin (2)	2018	29712651
Ct1	C. tropicalis	Clinical isolate	FKS1	S647G	Single substitution	B6S6L8	1904	Model		Micafungin (0.25), Anidulafungin (0.064)	2018	29712651
Ct2	C. tropicalis	Clinical isolate	FKS1	S645F	Single substitution	B6S6L8	1904	Model	Mismatch residue	Micafungin (2), Anidulafungin (1)	2018	29712651
Ct3	C. tropicalis	Clinical isolate	FKS1	F641L	Single substitution	B6S6L8	1904	Model	Mismatch residue	Micafungin (0.25), Anidulafungin (0.064)	2018	29712651
IHEM 26116	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25)	2018	29784839
Ca	C. albicans	Clinical isolate	FKS1	R1361G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1), Anidulafungin (0.5), Micafungin (0.5)	2018	29909005
Cg	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8), Anidulafungin (2), Micafungin (4)	2018	29909005
isoalte 1	C. albicans	Clinical isolate	FKS1	S645F	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.38), Micafungin (0.08)	2018	29941644
isoalte 10	C. glabrata	Clinical isolate	FKS2	L1381S	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.19), Anidulafungin (0.023), Micafungin (0.006)	2018	29941644
isoalte 2	C. albicans	Clinical isolate	FKS1	R1360K	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.38)	2018	29941644
isoalte 3	C. albicans	Clinical isolate	FKS1	R1360K	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (0.19)	2018	29941644
isoalte 4	C. orthopsilosis	Clinical isolate	FKS1	V1364I	Single substitution	H8X1R5	1902	Model		Caspofungin (3), Anidulafungin (3), Anidulafungin (0.25)	2018	29941644
isoalte 5	C. orthopsilosis	Clinical isolate	FKS1	V1364I, R1365T	Double substitution	H8X1R5	1902	Model		Caspofungin (3), Anidulafungin (0.75), Micafungin (0.19)	2018	29941644
isoalte 6	C. parapsilosis	Clinical isolate	FKS1	A660P	Single substitution	A9YLC3	1909	Model		Caspofungin (>32), Anidulafungin (3), Micafungin (0.38)	2018	29941644
isoalte 7	C. glabrata	Clinical isolate	FKS2	L660F	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.047).Anidulafungin (0.032), Micafungin (0.004)	2018	29941644
isoalte 8	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (32), Anidulafungin (8), Anidulafungin (4)	2018	29941644
isoalte 9	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32), Anidulafungin (32), Anidulafungin (12)	2018	29941644
R1	C. parapsilosis	Clinical isolate	MRR1	G583R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (>64)	2018	30124412
R10	C. parapsilosis	Clinical isolate	TAC1	N900D	Single substitution	G8B9R1	980	AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R11	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	R398I P250S L877P	Single substitution Single substitution Single substitution	G8B9T3 G8BAV4 G8B9R1	522 1128 980	AF-G8B9T3-F1 AF-G8BAV4-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R12	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	R398I S1081P L877P	Single substitution Single substitution Single substitution	G8B9T3 G8BAV4 G8B9R1	522 1128 980	AF-G8B9T3-F1 AF-G8BAV4-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R13	C. parapsilosis	Clinical isolate	ERG11 UPC2	R398I D394N	Single substitution Single substitution	G8B9T3 G8BCU0	522 847	AF-G8B9T3-F1 AF-G8BCU0-F1		Fluconazole (8)	2018	30124412
R14	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	R398I P295R L877P	Single substitution Single substitution Single substitution	G8B9T3 G8BAV4 G8B9R1	522 1128 980	AF-G8B9T3-F1 AF-G8BAV4-F1 AF-G8B9R1-F1		Fluconazole (32)	2018	30124412
R15	C. parapsilosis	Clinical isolate	ERG11	R398I	Single substitution	G8B9T3	522	AF-G8B9T3-F1		Fluconazole (16)	2018	30124412
R16	C. parapsilosis	Clinical isolate	ERG11 MRR1	K128N W872C	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (32)	2018	30124412
R17	C. parapsilosis	Clinical isolate	MRR1	G927D	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2018	30124412
R2	C. parapsilosis	Clinical isolate	MRR1	G583R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2018	30124412
R3	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R5	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R6	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (16)	2018	30124412
R7	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R8	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
R9	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I L877P	Single substitution Single substitution	G8B9T3 G8B9R1	522 980	AF-G8B9T3-F1 AF-G8B9R1-F1		Fluconazole (8)	2018	30124412
Y1	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y10	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (16-32)	2018	30124412
Y11	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (16-32)	2018	30124412
Y12	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y13	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y14	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y15	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y16	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y17	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y18	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y19	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y2	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y20	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y21	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y22	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, Q1053del	Single substitution Complex	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-16)	2018	30124412
Y23	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, Q1053del	Single substitution Complex	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-16)	2018	30124412
Y24	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, Q1053del	Single substitution Complex	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-16)	2018	30124412
Y25	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2018	30124412
Y26	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (64)	2018	30124412
Y27	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (32)	2018	30124412
Y28	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2018	30124412
Y29	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2018	30124412
Y3	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y30	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (64)	2018	30124412
Y4	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y5	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y6	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y7	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y8	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8-32)	2018	30124412
Y9	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (16-32)	2018	30124412
AD/CaCDR1	C. albicans	Laboratory strain	CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1 CDR1	A713P C712S F1235C G547R N1240D N535I Q1388P Q714P R546T R546Y S542L S542P T540I V1322A V1322G W1295S Y544F	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3 Q5ANA3	1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501 1501	AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1 AF-Q5ANA3-F1		Fluconazole (512) Fluconazole (256) Fluconazole (1024) Fluconazole (128)	2018	30348662
044Fluco45	C. glabrata	Clinical isolate	PDR1	Y372C	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (8), Posaconazole (16), Clotrimazole (32)	2018	30348666
VPCI 1132/P/13	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (4)	2019	30397051
VPCI 1133/P/13-R	C. auris	Clinical isolate	ERG11 FKS1	K143R S639F	Single substitution Single substitution	A0A2H1A309 A0A2H1A4W2	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>128), Voriconazole (0.5), Micafungin (16), Anidulafungin (>16), Caspofungin (8)	2019	30397051
Cg	C. glabrata	Clinical isolate	FKS1	V1342I	Single substitution	Q6FTN8	1863	Model		Micafungin (0.5)	2019	30401513
Kw1856/15	C. glabrata	Clinical isolate	ERG2 ERG6	I207V W286del	Single substitution Deletion	Q6FKL1 Q6FRZ7	224 372	AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (1.5)], CLSI[Amphotericin B (1)]	2019	30455247
Kw2516/15	C. glabrata	Clinical isolate	ERG2 ERG6	I207V C198F	Single substitution Single substitution	Q6FKL1 Q6FRZ7	224 372	AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (1.5)], CLSI[Amphotericin B (1)]	2019	30455247
Kw2813/15	C. glabrata	Clinical isolate	ERG2 ERG6	I207V Y192del	Single substitution Deletion	Q6FKL1 Q6FRZ7	224 372	AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (4)], CLSI[Amphotericin B (1)]	2019	30455247
Kw3060/15	C. glabrata	Clinical isolate	ERG2	I207V, G119S	Double substitution	Q6FKL1	224	AF-Q6FKL1-F1		Etest[Amphotericin B (1.5)], CLSI[Amphotericin B (1)]	2019	30455247
Kw3357/15	C. glabrata	Clinical isolate	ERG2 ERG6	I207V W286del	Single substitution Deletion	Q6FKL1 Q6FRZ7	224 372	AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (2)], CLSI[Amphotericin B (1)]	2019	30455247
Kw844/10	C. glabrata	Clinical isolate	ERG2	I207V, G122S	Double substitution	Q6FKL1	224	AF-Q6FKL1-F1		Etest[Amphotericin B (1.5)], CLSI[Amphotericin B (1)]	2019	30455247
Kw861/13	C. glabrata	Clinical isolate	ERG11 ERG2 ERG6	Y141H, L381M I207V L341del	Double substitution Single substitution Deletion	P50859 Q6FKL1 Q6FRZ7	533 224 372	5JLC AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (1)], CLSI[Amphotericin B (1), Fluconazole (>64), Voriconazole (2), Itraconazole (0.5), Isavuconazole (0.5)]	2019	30455247
Kw96/15	C. glabrata	Clinical isolate	ERG2 ERG6	I207V V126F	Single substitution Single substitution	Q6FKL1 Q6FRZ7	224 372	AF-Q6FKL1-F1 AF-Q6FRZ7-F1		Etest[Amphotericin B (2)], CLSI[Amphotericin B (1)]	2019	30455247
N=1 isolate	C. tropicalis	Clinical isolate	ERG11 ERG11	G464S V125A	Single substitution Single substitution	C5MGS9 C5MGS9	528 528	AF-C5MGS9-F1 AF-C5MGS9-F1		Fluconazole (8)	2019	30472420
N=16 isolates	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2019	30472420
N=38 isolates	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2019	30472420
N=5 isolates	C. tropicalis	Clinical isolate	ERG11	Y257H	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (8)	2019	30472420
CL1	C. lusitaniae	Laboratory strain	FKS1	F634V	Single substitution	A0A202G441	1886	Model		Caspofungin (1.5)	2019	30517635
CL2	C. lusitaniae	Laboratory strain	FKS1	S638P	Single substitution	A0A202G441	1886	Model		Caspofungin (≥32)	2019	30517635
CL3	C. lusitaniae	Laboratory strain	FKS1	R1352G	Single substitution	A0A202G441	1886	Model		Caspofungin (≥32)	2019	30517635
CL4	C. lusitaniae	Laboratory strain	FKS1	F634del	Deletion	A0A202G441	1886	Model		Caspofungin (32)	2019	30517635
CL5	C. lusitaniae	Laboratory strain	FKS1	P642A	Single substitution	A0A202G441	1886	Model		Caspofungin (0.75)	2019	30517635
WM_ 03.419	C. glabrata	Clinical isolate	FCY2 FKS2 FKS3 PDR1	A237T F384Y R672K S76P, L98S, L139I, T143P	Single substitution Single substitution Single substitution Multiple substitution	Q6FPL2 Q6FMZ3 Q6FIJ9 Q6FXU7	515 1897 1840 1107	AF-Q6FPL2-F1 Model Model AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (2), Posaconazole (1)	2018	30559734
WM_ 03.449	C. glabrata	Clinical isolate	FCY2 FKS3 FPS2 PDR1	A237T I3T, L884V, R1472Q, Y1731C Q533H S76P, L98S, T143P	Single substitution Multiple substitution Single substitution Multiple substitution	Q6FPL2 Q6FIJ9 Q6FV88 Q6FXU7	515 1840 602 1107	AF-Q6FPL2-F1 Model AF-Q6FV88-F1 AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1)	2018	30559734
WM_ 04.113	C. glabrata	Clinical isolate	CDR1 FKS1 FKS3 PDR1	M638I, N1108S S502F I3T, A42G, L884V, R1472Q, A1645V, Y1731C P695L	Double substitution Single substitution Multiple substitution Single substitution	Q6FK23 Q6FTN8 Q6FIJ9 Q6FXU7	1499 1863 1840 1107	AF-Q6FK23-F1 Model Model AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (2), Posaconazole (2)	2018	30559734
WM_ 05.113	C. glabrata	Clinical isolate	FCY2 FKS3 FPS1 PDR1	A237T I3T, L884V, R1472Q, Y1731C Q533H S76P, L98S, T143P	Single substitution Multiple substitution Single substitution Multiple substitution	Q6FPL2 Q6FIJ9 Q6FWS6 Q6FXU7	515 1840 652 1107	AF-Q6FPL2-F1 Model AF-Q6FWS6-F1 AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1)	2018	30559734
WM_ 18.24	C. glabrata	Clinical isolate	FCY2 FKS1 FPS1 FPS2 MSH2 PDR1	I384F S629P A316S A409T, D517Y L269F S76P, L98S, T143P	Single substitution Single substitution Single substitution Double substitution Single substitution Multiple substitution	Q6FPL2 Q6FTN8 Q6FWS6 Q6FV88 Q6FQA9 Q6FXU7	515 1863 652 602 957 1107	AF-Q6FPL2-F1 Model AF-Q6FWS6-F1 AF-Q6FV88-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Caspofungin (8)	2018	30559734
WM_ 18.26	C. glabrata	Clinical isolate	FKS2 FPS1 FPS2 PDR1	S663P A316S A409T, D517Y S76P, L98S, T143P	Single substitution Single substitution Double substitution Multiple substitution	Q6FMZ3 Q6FWS6 Q6FV88 Q6FXU7	1897 652 602 1107	Model AF-Q6FWS6-F1 AF-Q6FV88-F1 AF-Q6FXU7-F1		Amphotericin B (2), Caspofungin (>8)	2018	30559734
WM_ 18.27	C. glabrata	Clinical isolate	CDR1 ERG9 FCY2 FKS3 FPS2 PDR1	H58Y C128F A237T I3T, L884V, R1472Q, Y1731C Q533H S76P, L98S, T143P	Single substitution Single substitution Single substitution Multiple substitution Single substitution Multiple substitution	Q6FK23 Q9HGZ6 Q6FPL2 Q6FIJ9 Q6FV88 Q6FXU7	1499 443 515 1840 602 1107	AF-Q6FK23-F1 AF-Q9HGZ6-F1 AF-Q6FPL2-F1 Model AF-Q6FV88-F1 AF-Q6FXU7-F1		Fluconazole (256), Voriconazole (8), Posaconazole (>8)	2018	30559734
WM_ 18.33	C. glabrata	Clinical isolate	CDR1 PDR1	H58Y N768D	Single substitution Single substitution	Q6FK23 Q6FXU7	1499 1107	AF-Q6FK23-F1 AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (2), Posaconazole (>8)	2018	30559734
WM_ 18.40	C. glabrata	Clinical isolate	CDR1 FCY2 FKS3 FPS2 PDR1	H58Y, N813Y A237T I3T, A42G, K206E, N865S, R1472Q, F1768I A409T, A227S, N18D S76P, L98S, T143P	Double substitution Single substitution Multiple substitution Multiple substitution Multiple substitution	Q6FK23 Q6FPL2 Q6FIJ9 Q6FV88 Q6FXU7	1499 515 1840 602 1107	AF-Q6FK23-F1 AF-Q6FPL2-F1 Model AF-Q6FV88-F1 AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (2), Posaconazole (>8)	2018	30559734
WM_ 18.42	C. glabrata	Clinical isolate	CDR1 FKS1 FKS3 PDR1	M638I, N1108S S502F I3T, A42G, L884V, R1472Q, A1645V, Y1731C R250K, G943D	Double substitution Single substitution Multiple substitution Double substitution	Q6FK23 Q6FTN8 Q6FIJ9 Q6FXU7	1499 1863 1840 1107	AF-Q6FK23-F1 Model Model AF-Q6FXU7-F1		Fluconazole (256), Voriconazole (8), Posaconazole (1)	2018	30559734
WM_ 18.49	C. glabrata	Clinical isolate	CDR1 ERG9 FCY2 FKS3 FPS2 PDR1	H58Y C128F A237T I3T, L884V, R1472Q, Y1731C Q533H S76P, L98S, T143P	Single substitution Single substitution Single substitution Multiple substitution Single substitution Multiple substitution	Q6FK23 Q9HGZ6 Q6FPL2 Q6FIJ9 Q6FV88 Q6FXU7	1499 443 515 1840 602 1107	AF-Q6FK23-F1 AF-Q9HGZ6-F1 AF-Q6FPL2-F1 Model AF-Q6FV88-F1 AF-Q6FXU7-F1		Fluconazole (256), Voriconazole (8), Posaconazole (>8)	2018	30559734
WM_ 18.51	C. glabrata	Clinical isolate	CDR1 FCY2 FKS3 FPS1 FPS2 PDR1	H58Y, I1478M A237T I3T, A42G, K206E, N865S, R1472Q, F1768I N27H A409T, A227S, N18D S76P, L98S, T143P, E259G	Double substitution Single substitution Multiple substitution Single substitution Multiple substitution Multiple substitution	Q6FK23 Q6FPL2 Q6FIJ9 Q6FWS6 Q6FV88 Q6FXU7	1499 515 1840 652 602 1107	AF-Q6FK23-F1 AF-Q6FPL2-F1 Model AF-Q6FWS6-F1 AF-Q6FV88-F1 AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (2), Posaconazole (>8)	2018	30559734
WM_ 18.53	C. glabrata	Clinical isolate	FKS1 FKS3 MSH2 PDR1	S502F I3T, A42G, L884V, R1472Q, A1645V, Y1731C E456D S76P, L98S, L139I, T143P	Single substitution Multiple substitution Single substitution Multiple substitution	Q6FTN8 Q6FIJ9 Q6FQA9 Q6FXU7	1863 1840 957 1107	Model Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (4), Posaconazole (>8)	2018	30559734
WM_ 18.63	C. glabrata	Clinical isolate	FKS1 FKS2 FKS3 FPS1 MSH2 PDR1	S629P E784G I3T, R1472Q, Y1731C, S1840Y A316S V239L, A942T S76P, L98S, T143P	Single substitution Single substitution Multiple substitution Single substitution Double substitution Multiple substitution	Q6FTN8 Q6FMZ3 Q6FIJ9 Q6FWS6 Q6FQA9 Q6FXU7	1863 1897 1840 652 957 1107	Model Model Model AF-Q6FWS6-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Caspofungin (2)	2018	30559734
WM_ 18.64	C. glabrata	Clinical isolate	FKS1 FKS2 FKS3 FPS1 MSH2 PDR1	S629P E784G I3T, R1472Q, Y1731C, S1840Y A316S V239L, A942T S76P, L98S, T143P	Single substitution Single substitution Multiple substitution Single substitution Double substitution Multiple substitution	Q6FTN8 Q6FMZ3 Q6FIJ9 Q6FWS6 Q6FQA9 Q6FXU7	1863 1897 1840 652 957 1107	Model Model Model AF-Q6FWS6-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Caspofungin (2)	2018	30559734
WM_ 18.65	C. glabrata	Clinical isolate	CDR1 PDR1	H58Y S76P, L98S, T143P	Single substitution Multiple substitution	Q6FK23 Q6FXU7	1499 1107	AF-Q6FK23-F1 AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1), Posaconazole (2)	2018	30559734
WM_ 18.66	C. glabrata	Clinical isolate	FCY2 FKS2 FKS3 PDR1	A237T F384Y N108Y, R672K S76P, L98S, L139I, T143P, W256G	Single substitution Single substitution Double substitution Multiple substitution	Q6FPL2 Q6FMZ3 Q6FIJ9 Q6FXU7	515 1897 1840 1107	AF-Q6FPL2-F1 Model Model AF-Q6FXU7-F1		Fluconazole (256), Voriconazole (8), Posaconazole (2)	2018	30559734
1131PC	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32), Voriconazole (0.5)	2018	30568646
137H	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (1)	2018	30568646
16PC	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (1)	2018	30568646
340PC	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (1)	2018	30568646
542AMO	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (1)	2018	30568646
87H	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (2)	2018	30568646
88H	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64), Voriconazole (1)	2018	30568646
Patient1/Isolate1	C. tropicalis	Clinical isolate	ERG11 FKS1 MDR1	Y132F, S154F F641L, M1235I P448L	Double substitution Double substitution Single substitution	P14263 B6S6L8 C5MAA0	528 1904 552	AF-P14263-F1 Model AF-C5MAA0-F1		Fluconazole (>256), Voriconazole (12), Anidulafungin (0.5)	2019	30583013
Patient2/Isolate2	C. tropicalis	Clinical isolate	ERG11 FKS1	Y257H D648V	Single substitution Single substitution	P14263 B6S6L8	528 1904	AF-P14263-F1 Model		Anidulafungin (0.25)	2019	30583013
Patient3/Isolate3	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Anidulafungin (0.5)	2019	30583013
Ca10	C. albicans	Clinical isolate	ERG11 TAC1	K143R G980E	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64), Posaconazole (1), Isavuconazole (0.5), Itraconazole (0.5), Voriconazole (0.25)	2020	30629653
Ca11	C. albicans	Clinical isolate	ERG11 TAC1	K143R G649D, F974L	Single substitution Double substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (64), Posaconazole (0.5), Isavuconazole (0.25), Itraconazole (1), Voriconazole (0.5)	2020	30629653
Ca12	C. albicans	Clinical isolate	ERG3	Y235stop, A353T	Complex	Q59VG6	386	AF-Q59VG6-F1	Structure not available	Anidulafungin (0.125), Caspofungin (0.064), Micafungin (0.064),	2020	30629653
Ca13	C. albicans	Clinical isolate	ERG3 GSC1	A353T F641C	Single substitution Single substitution	Q59VG6 A0A1D8PCT0	386 1897	AF-Q59VG6-F1 AF-A0A1D8PCT0-F1		Anidulafungin (0.125), Caspofungin (0.125), Micafungin (0.064)	2020	30629653
Ca14	C. albicans	Clinical isolate	ERG3 GSC1	A353T F641C	Single substitution Single substitution	Q59VG6 A0A1D8PCT0	386 1897	AF-Q59VG6-F1 AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (1), Micafungin (1)	2020	30629653
Ca15	C. albicans	Clinical isolate	GSC1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (2), Micafungin (1)	2020	30629653
Ca16	C. albicans	Clinical isolate	GSC1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (1), Micafungin (0.5)	2020	30629653
Ca17	C. albicans	Clinical isolate	GSC1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (2), Micafungin (2)	2020	30629653
Ca18	C. albicans	Clinical isolate	GSC1	P649H, M696V	Double substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.25), Caspofungin (0.5), Micafungin (0.5)	2020	30629653
Ca22	C. albicans	Clinical isolate	ERG3	Y190stop, A353T	Complex	Q59VG6	386	AF-Q59VG6-F1	Structure not available	Anidulafungin (0.25), Caspofungin (0.5), Micafungin (0.125), Fluconazole (>256), Posaconazole (>32), Isavuconazole (>16), Itraconazole (>16), Voriconazole (>8)	2020	30629653
Ca3	C. albicans	Clinical isolate	ERG11 ERG3 TAC1	F72L, Y132H A353T, T329S N977D	Double substitution Double substitution Single substitution	Q9P4W0 Q59VG6 A0A1D8PN96	528 386 981	AF-Q9P4W0-F1 AF-Q59VG6-F1 AF-A0A1D8PN96-F1		Fluconazole (128), Posaconazole (4), Isavuconazole (4), Itraconazole (>16), Voriconazole (8)	2020	30629653
Ca5	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>256), Posaconazole (>32), Isavuconazole (>16), Itraconazole (>16), Voriconazole (>8)	2020	30629653
Ca6	C. albicans	Clinical isolate	ERG11 ERG3 TAC1	V437I S191P S937L	Single substitution Single substitution Single substitution	Q9P4W0 Q59VG6 A0A1D8PN96	528 386 981	AF-Q9P4W0-F1 AF-Q59VG6-F1 AF-A0A1D8PN96-F1		Fluconazole (128), Posaconazole (>32), Isavuconazole (>16), Itraconazole (>16), Voriconazole (>8)	2020	30629653
Ca8	C. albicans	Clinical isolate	ERG11 TAC1	Y132H N740D	Single substitution Single substitution	Q9P4W0 A0A1D8PN96	528 981	AF-Q9P4W0-F1 AF-A0A1D8PN96-F1		Fluconazole (128), Posaconazole (0.25), Isavuconazole (0.5), Itraconazole (1), Voriconazole (8)	2020	30629653
Ca9	C. albicans	Clinical isolate	ERG11 ERG3	E208K, T525I G261E	Double substitution Single substitution	Q9P4W0 Q59VG6	528 386	AF-Q9P4W0-F1 AF-Q59VG6-F1		Fluconazole (>256), Posaconazole (>32), Isavuconazole (>16), Itraconazole (>16), Voriconazole (>8)	2020	30629653
cg26	C. glabrata	Clinical isolate	PDR1	G1079R	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16), Voriconazole (4)	2020	30629653
cg28	C. glabrata	Clinical isolate	PDR1	D876Y, G1079V	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16), Voriconazole (4)	2020	30629653
cg29	C. glabrata	Clinical isolate	FKS1	K1323E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.125), Caspofungin (0.125), Micafungin (0.064), Fluconazole (128), Posaconazole (16), Isavuconazole (8), Itraconazole (8), Voriconazole (8)	2020	30629653
cg30	C. glabrata	Clinical isolate	PDR1	G348D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16), Voriconazole (8)	2020	30629653
cg31	C. glabrata	Clinical isolate	PDR1	L291P	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16), Voriconazole (4)	2020	30629653
cg33	C. glabrata	Clinical isolate	PDR1	G348S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (16), Itraconazole (>16), Voriconazole (8)	2020	30629653
cg34	C. glabrata	Clinical isolate	PDR1	Y372H	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16, Voriconazole (8)	2020	30629653
cg35	C. glabrata	Clinical isolate	PDR1	G346D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16, Voriconazole (8)	2020	30629653
cg36	C. glabrata	Clinical isolate	PDR1	H288D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16, Voriconazole (8)	2020	30629653
cg37	C. glabrata	Clinical isolate	PDR1	G346A	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (16), Itraconazole (>16), Voriconazole (>8)	2020	30629653
cg38	C. glabrata	Clinical isolate	PDR1	G348S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256), Posaconazole (>32), Isavuconazole (8), Itraconazole (>16), Voriconazole (8)	2020	30629653
cg41	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (2), Micafungin (0.016)	2020	30629653
cg45	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2020	30629653
cg46	C. glabrata	Clinical isolate	FKS1 PDR1	F625S W297R	Single substitution Single substitution	Q6FTN8 Q6FXU7	1863 1107	Model AF-Q6FXU7-F1		Anidulafungin (1), Caspofungin (2), Micafungin (0.25), Fluconazole (128), Posaconazole (32), Isavuconazole (8), Itraconazole (>16), Voriconazole (4)	2020	30629653
cg47	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (4), Fluconazole (128), Posaconazole (32), Isavuconazole (4), Itraconazole (>16), Voriconazole (4)	2020	30629653
cg48	C. glabrata	Clinical isolate	FKS1	K1323E	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.125), Fluconazole (128), Posaconazole (8), Isavuconazole (4), Itraconazole (8), Voriconazole (4)	2020	30629653
cg49	C. glabrata	Clinical isolate	PDR1	V329F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Anidulafungin (0.064), Caspofungin (0.125), Micafungin (0.125), Fluconazole (128), Posaconazole (>32), Isavuconazole (16), Itraconazole (>16), Voriconazole (8)	2020	30629653
cg50	C. glabrata	Clinical isolate	FKS2 PDR1	F659S G1088E	Single substitution Single substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Anidulafungin (0.25), Caspofungin (0.5), Micafungin (0.064), Fluconazole (256), Posaconazole (16), Isavuconazole (8), Itraconazole (4), Voriconazole (4)	2020	30629653
cg51	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (>16), Micafungin (4)	2020	30629653
CG25	C. glabrata	Clinical isolate	PDR1	N768D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (1), Ketoconazole (2)	2019	30658200
CGL4	C. glabrata	Clinical isolate	PDR1	L139I, E818K	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Itraconazole (1), Ketoconazole (1)	2019	30658200
A10	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A3	C. auris	Clinical isolate	ERG11	F126L, V125A	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A4	C. auris	Clinical isolate	ERG11	F126L, V125A	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A5	C. auris	Clinical isolate	ERG11	Y132F, K177R, N335S, E343D	Multiple substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A6	C. auris	Clinical isolate	ERG11	Y132F, K177R, N335S, E343D	Multiple substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A8	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
A9	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2019	30728190
VPCI 29/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 30/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 31/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 32/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 33/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 34/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 35/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 36/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 37/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 38/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 39/15	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 40/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 41/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 42/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 43/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 44/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 45/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 46/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 47/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 48/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 49/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 50/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 51/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 52/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 53/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 54/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2019	30753525
VPCI 55/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 56/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 57/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 58/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 59/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 60/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 61/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 62/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 63/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 64/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 65/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 66/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 67/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 68/17	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 69/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 70/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 71/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 72/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 73/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 74/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 75/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 76/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 77/15	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 78/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 79/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 80/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 81/15	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2019	30753525
VPCI 82/16	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2019	30753525
VPCI 83/15	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2019	30753525
IB014	C. albicans	Clinical isolate	FKS1	L644V, R647K, R1360L	Multiple substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1.5)	2019	30794951
IB059	C. albicans	Clinical isolate	FKS1	L642V, L644V, D648S, T1363G	Multiple substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2019	30794951
IB075	C. albicans	Clinical isolate	FKS1	T643I, R1360L, R1361L	Multiple substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2019	30794951
IB108	C. albicans	Clinical isolate	FKS1	T643I, L644G, D648S, W1358S, R1361L	Multiple substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1.5)	2019	30794951
Ca1	C. albicans	Clinical isolate	FKS1	F641I	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1)	2019	30895218
Ca2	C. albicans	Clinical isolate	FKS1	S629P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1	Mismatch residue	Anidulafungin (0.5), Caspofungin (2), Micafungin (1)	2019	30895218
Ca3	C. albicans	Clinical isolate	FKS1	S654P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (1), Micafungin (1)	2019	30895218
Ca4	C. albicans	Clinical isolate	FKS1	F641S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Ca5	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.5), Caspofungin (1), Micafungin (1)	2019	30895218
Ca6	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.12), Caspofungin (1), Micafungin (1)	2019	30895218
Ca7	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.25), Caspofungin (1), Micafungin (1)	2019	30895218
Ca8	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (0.25), Caspofungin (1), Micafungin (1)	2019	30895218
Cd	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	D3IZZ7	1897	Model	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (1)	2019	30895218
Cg1	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	30895218
Cg10	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.12)	2019	30895218
Cg11	C. glabrata	Clinical isolate	FKS2	S659Y	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	30895218
Cg12	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Cg13	C. glabrata	Clinical isolate	FKS2	L644W	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Cg14	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2019	30895218
Cg15	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (4)	2019	30895218
Cg16	C. glabrata	Clinical isolate	FKS2	F641V	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (1), Caspofungin (4)	2019	30895218
Cg17	C. glabrata	Clinical isolate	FKS2	S663Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Cg18	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (4), Caspofungin (16), Micafungin (2)	2019	30895218
Cg19	C. glabrata	Clinical isolate	FKS2	D648E	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (0.25), Caspofungin (0.5)	2019	30895218
Cg2	C. glabrata	Clinical isolate	FKS1	R631S, S629P	Double substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2019	30895218
Cg20	C. glabrata	Clinical isolate	FKS1	F625Y	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (0.25)	2019	30895218
Cg21	C. glabrata	Clinical isolate	FKS2	F641Y	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (0.25)	2019	30895218
Cg22	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2019	30895218
Cg23	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Cg24	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (0.5)	2019	30895218
Cg25	C. glabrata	Clinical isolate	FKS2	D666E, K753Q	Double substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.5)	2019	30895218
Cg26	C. glabrata	Clinical isolate	FKS1	D632V	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2019	30895218
Cg27	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	30895218
Cg28	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (16), Micafungin (4)	2019	30895218
Cg29	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (0.5), Micafungin (1)	2019	30895218
Cg3	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1)	2019	30895218
Cg30	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (1)	2019	30895218
Cg31	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (8), Micafungin (2)	2019	30895218
Cg32	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (0.5), Micafungin (0.25)	2019	30895218
Cg33	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	30895218
Cg34	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2019	30895218
Cg35	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2019	30895218
Cg36	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	30895218
Cg37	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2019	30895218
Cg38	C. glabrata	Clinical isolate	FKS1 FKS2	F625S F659Y	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2019	30895218
Cg39	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (4), Micafungin (1)	2019	30895218
Cg4	C. glabrata	Clinical isolate	FKS1	L630I	Single substitution	Q6FTN8	1863	Model		Anidulafungin (0.5), Caspofungin (1), Micafungin (0.12)	2019	30895218
Cg40	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (2)	2019	30895218
Cg41	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (0.5)	2019	30895218
Cg42	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (1)	2019	30895218
Cg43	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (>8), Micafungin (4)	2019	30895218
Cg44	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Caspofungin (0.5)	2019	30895218
Cg45	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.25)	2019	30895218
Cg46	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (2)	2019	30895218
Cg47	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2019	30895218
Cg48	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (2)	2019	30895218
Cg49	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.12)	2019	30895218
Cg5	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (16), Micafungin (2)	2019	30895218
Cg50	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (8), Micafungin (2)	2019	30895218
Cg51	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (4), Micafungin (1)	2019	30895218
Cg6	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (2)	2019	30895218
Cg7	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	30895218
Cg8	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	30895218
Cg9	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2019	30895218
Ck1	C. kefyr	Clinical isolate	FKS1	R1344S	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (0.5), Micafungin (1)	2019	30895218
Ct1	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Ct2	C. tropicalis	Clinical isolate	FKS1	F641S	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (2), Caspofungin (2), Micafungin (1)	2019	30895218
Ct3	C. tropicalis	Clinical isolate	FKS1	F641L	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2019	30895218
Ct4	C. tropicalis	Clinical isolate	FKS1	F650S	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (2), Micafungin (1)	2019	30895218
Ct5	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (>8), Micafungin (2)	2019	30895218
Ct6	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (4), Micafungin (1)	2019	30895218
Ct7	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (0.5), Caspofungin (4), Micafungin (1)	2019	30895218
Ct8	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	30895218
Ct9	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	30895218
159MIR	C. glabrata	Clinical isolate	PDR1	E555K	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1), Voriconazole (4)	2019	30936110
22BC	C. glabrata	Clinical isolate	ERG11 PDR1	K456R, G457C, V458F N162S, F944S	Multiple substitution Double substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (1)	2019	30936110
2BC	C. glabrata	Clinical isolate	ERG11 PDR1	N368T T745A, C930R	Single substitution Double substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (0.5)	2019	30936110
33BC	C. glabrata	Clinical isolate	PDR1	G574S	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1)	2019	30936110
348MIR	C. glabrata	Clinical isolate	ERG11	N368T	Single substitution	P50859	533	5JLC	Structure not available	Caspofungin (1), Voriconazole (2)	2019	30936110
40BC	C. glabrata	Clinical isolate	PDR1	P68S, P135T, D235N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Mismatch residue	Caspofungin (1)	2019	30936110
42BC	C. glabrata	Clinical isolate	PDR1	P68S, P135T, D235N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Mismatch residue	Caspofungin (1)	2019	30936110
44BC	C. glabrata	Clinical isolate	ERG11 PDR1	N368T C930R	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (1)	2019	30936110
45-1BC	C. glabrata	Clinical isolate	PDR1	C930R	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1)	2019	30936110
45-2BC	C. glabrata	Clinical isolate	PDR1	C930R	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
51 -1BC	C. glabrata	Clinical isolate	PDR1	P117S	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Mismatch residue	Caspofungin (0.5)	2019	30936110
692MIR	C. glabrata	Clinical isolate	PDR1	K67N	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Mismatch residue	Voriconazole (2)	2019	30936110
70BC	C. glabrata	Clinical isolate	ERG11	N368T, H430P	Double substitution	P50859	533	5JLC	Structure not available	Caspofungin (0.5)	2019	30936110
721MIR	C. glabrata	Clinical isolate	ERG11	N368T	Single substitution	P50859	533	5JLC	Structure not available	Voriconazole (1), Caspofungin (0.5)	2019	30936110
88 -2BC	C. glabrata	Clinical isolate	PDR1	C930R	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Voriconazole (1), Caspofungin (1)	2019	30936110
N145	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
N172	C. glabrata	Clinical isolate	ERG11 PDR1	N368T T745A	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Voriconazole (1), Caspofungin (0.5)	2019	30936110
N177	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1)	2019	30936110
N194	C. glabrata	Clinical isolate	ERG11 PDR1	N368T T745A	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (0.5)	2019	30936110
N198s	C. glabrata	Clinical isolate	ERG11 PDR1	N368T T745A	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (0.5)	2019	30936110
N73	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
SU -103	C. glabrata	Clinical isolate	PDR1	K430M, L454P	Double substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
SU -113	C. glabrata	Clinical isolate	PDR1	K430M, E441K	Double substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
SU -232(2)	C. glabrata	Clinical isolate	ERG11 PDR1	D196N A1004S	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (1)	2019	30936110
Su 261	C. glabrata	Clinical isolate	PDR1	A828T	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (0.5)	2019	30936110
SU-227(1)	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Fluconazole (64)	2019	30936110
SU-227(2)	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1)	2019	30936110
SU-249	C. glabrata	Clinical isolate	PDR1	T745A	Single substitution	Q66WF3	1107	AF-Q66WF3-F1	Structure not available	Caspofungin (1)	2019	30936110
SU-260	C. glabrata	Clinical isolate	ERG11	N368T	Single substitution	P50859	533	5JLC	Structure not available	Caspofungin (0.5)	2019	30936110
SU-39	C. glabrata	Clinical isolate	ERG11 PDR1	H430P G189V	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (0.5)	2019	30936110
SU-72	C. glabrata	Clinical isolate	ERG11 PDR1	H430P G128E, G493A	Single substitution Double substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (1)	2019	30936110
SU-80	C. glabrata	Clinical isolate	ERG11 PDR1	H430P G128E	Single substitution Single substitution	P50859 Q66WF3	533 1107	5JLC AF-Q66WF3-F1		Caspofungin (0.5)	2019	30936110
isolate no. 61	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	W8CTF4	233	AF-W8CTF4-F1	Structure not available	Caspofungin (8), Micafungin (1)	2020	31111912
isolate no. 71	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663F	Single substitution Single substitution	W8CTF4 E2GKZ6	233 1897	AF-W8CTF4-F1 Model		Anidulafungin (0.5), Caspofungin (1)	2020	31111912
isolate no. 72	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663F	Single substitution Single substitution	W8CTF4 E2GKZ6	233 1897	AF-W8CTF4-F1 Model		Anidulafungin (2), Caspofungin (32), Micafungin (4)	2020	31111912
isolate no. 73	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (4)	2020	31111912
isolate no. 74	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (2)	2020	31111912
isolate no. 75	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	W8CTF4	233	AF-W8CTF4-F1	Structure not available	Anidulafungin (0.5), Caspofungin (2), Micafungin (0.25)	2020	31111912
isolate no. 76	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	W8CTF4	233	AF-W8CTF4-F1	Structure not available	Anidulafungin (0.5), Caspofungin (4), Micafungin (0.5)	2020	31111912
isolate no. 78	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.75)	2020	31111912
isolate no. 79	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2020	31111912
isolate no. 81	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	W8CTF4	233	AF-W8CTF4-F1	Structure not available	Anidulafungin (0.5), Caspofungin (2), Micafungin (0.125)	2020	31111912
NCPF no. 8814	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (4), Caspofungin (6), Micafungin (1)	2020	31111912
NCPF no. 8919	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (6), Caspofungin (>32), Micafungin (6)	2020	31111912
35	C. glabrata	Clinical isolate	PDR1	D876N	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (8), Itraconazole (>4), Fluconazole (128)	2019	31118695
44	C. glabrata	Clinical isolate	PDR1	N764D	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (8), Itraconazole (4), Fluconazole (128)	2019	31118695
50	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (8), Itraconazole (>4), Fluconazole (64)	2019	31118695
51	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
53	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (8), Itraconazole (>4), Fluconazole (128)	2019	31118695
54	C. glabrata	Clinical isolate	PDR1	G348C	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (8), Itraconazole (>4), Fluconazole (64)	2019	31118695
55	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
56	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
57	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
58	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
59	C. glabrata	Clinical isolate	PDR1	A848V	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		5-Flucytosine (>4), Voriconazole (4), Itraconazole (>4), Fluconazole (64)	2019	31118695
CA-n1	C. albicans	Clinical isolate	ERG11	P56S, V88I	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1	Mismatch residue	Posaconazole, Itraconazole, Fluconazole	2019	31174994
CA-n3	C. albicans	Clinical isolate	ERG11	A114S, Y257H	Double substitution	Q9P4W0	528	AF-Q9P4W0-F1		Posaconazole, Itraconazole, Fluconazole	2019	31174994
CT-n1	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	P14263	528	AF-P14263-F1		Posaconazole, Fluconazole	2019	31174994
RCPF1821	C. auris	Clinical isolate	ERG11	F105L, K143R	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2020	31290551
CDC0383_Africa1	C. auris	Clinical isolate	ERG11	F124L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (128), Voriconazole (4)	2019	31325309
CDC0384_Africa2	C. auris	Clinical isolate	ERG11	F124L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (128), Voriconazole (1)	2019	31325309
CDC0385_South America1	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Voriconazole (16)	2019	31325309
CDC0385_South America2	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Voriconazole (16)	2019	31325309
CDC0385_South America3	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Voriconazole (2)	2019	31325309
CDC0385_South America4	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (4)	2019	31325309
CDC0385_South America5	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Voriconazole (8)	2019	31325309
cg	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2019	31345844
CNM-CL10047	C. glabrata	Clinical isolate	FKS2	F659del, D666N	Complex	Q6FMZ3	1897	Model		Anidulafungin (>4), Micafungin (2), Fluconazole (64)	2019	31354675
CNM-CL9646	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.06), Fluconazole (64)	2019	31354675
CNM-CL9775	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.06)	2019	31354675
CNM-CL9877	C. glabrata	Clinical isolate	FKS2	L664R	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.06)	2019	31354675
CNM-CL9883	C. glabrata	Clinical isolate	FKS2	D666E	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Micafungin (0.06)	2019	31354675
CNM-CL9889	C. glabrata	Clinical isolate	FKS2	L664R	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125), Micafungin (0.125)	2019	31354675
CNM-CL9897	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (>2)	2019	31354675
CNM-CL9931	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (2)	2019	31354675
CNM-CL9932	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (2)	2019	31354675
CNM-CL9939	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (2), Fluconazole (64)	2019	31354675
CNM-CL9975	C. glabrata	Clinical isolate	FKS2	D666H	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125)	2019	31354675
CNM-CL9981	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (>2)	2019	31354675
CNM-CL9988	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.25), Micafungin (0.06)	2019	31354675
CNM-CL9991	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (2), Fluconazole (>64)	2019	31354675
CNM-CL9992	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (>2), Fluconazole (64)	2019	31354675
ISOALTE 32	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOALTE 46	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (4), Micafungin (1)	2019	31481447
ISOALTE 8	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (16), Micafungin (4)	2019	31481447
ISOALTE 89	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	31481447
ISOLATE 1	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2019	31481447
ISOLATE 10	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25)	2019	31481447
ISOLATE 11	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2019	31481447
ISOLATE 12	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2019	31481447
ISOLATE 13	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.125)	2019	31481447
ISOLATE 14	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (1), Micafungin (2)	2019	31481447
ISOLATE 15	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2019	31481447
ISOLATE 16	C. glabrata	Clinical isolate	FKS1 FKS2	R631G D666V	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.5)	2019	31481447
ISOLATE 17	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.5)	2019	31481447
ISOLATE 18	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (8), Micafungin (2)	2019	31481447
ISOLATE 19	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (1), Micafungin (2)	2019	31481447
ISOLATE 2	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	31481447
ISOLATE 20	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.06), Caspofungin (0.125), Micafungin (0.25)	2019	31481447
ISOLATE 21	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.25), Caspofungin (0.5), Micafungin (1)	2019	31481447
ISOLATE 22	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 23	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 24	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 25	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2019	31481447
ISOLATE 28	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (0.5), Micafungin (0.125)	2019	31481447
ISOLATE 29	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.06), Caspofungin (0.125), Micafungin (0.25)	2019	31481447
ISOLATE 3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2019	31481447
ISOLATE 30	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 31	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (0.125), Micafungin (0.125)	2019	31481447
ISOLATE 33	C. glabrata	Clinical isolate	FKS2	del658F	Deletion	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (0.5), Micafungin (0.25)	2019	31481447
ISOLATE 36	C. glabrata	Clinical isolate	FKS1 FKS2	R631G S663P	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (2), Caspofungin (16), Micafungin (4)	2019	31481447
ISOLATE 37	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (16), Micafungin (2)	2019	31481447
ISOLATE 38	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (2), Caspofungin (4), Micafungin (1)	2019	31481447
ISOLATE 39	C. glabrata	Clinical isolate	FKS2	del658F	Deletion	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (16), Micafungin (>16)	2019	31481447
ISOLATE 4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (4)	2019	31481447
ISOLATE 40	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (2), Micafungin (1)	2019	31481447
ISOLATE 41	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (16), Micafungin (4)	2019	31481447
ISOLATE 42	C. glabrata	Clinical isolate	FKS1	D632V	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (1), Micafungin (0.25)	2019	31481447
ISOLATE 45	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (16), Micafungin (2)	2019	31481447
ISOLATE 48	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (0.125), Caspofungin (0.125), Micafungin (0.5)	2019	31481447
ISOLATE 5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (16), Micafungin (4)	2019	31481447
ISOLATE 50	C. glabrata	Clinical isolate	FKS1 FKS2	S629T F659Y	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (2), Caspofungin (4), Micafungin (0.125)	2019	31481447
ISOLATE 53	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 54	C. glabrata	Clinical isolate	FKS1	I634V	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.03), Caspofungin (0.06), Micafungin (0.25)	2019	31481447
ISOLATE 55	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (2)	2019	31481447
ISOLATE 57	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2019	31481447
ISOLATE 59	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (0.5), Caspofungin (1), Micafungin (0.25)	2019	31481447
ISOLATE 6	C. glabrata	Clinical isolate	FKS2	P667H	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (0.25)	2019	31481447
ISOLATE 61	C. glabrata	Clinical isolate	FKS1	D632Y	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (2), Micafungin (0.25)	2019	31481447
ISOLATE 62	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 63	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (1), Caspofungin (2), Micafungin (1)	2019	31481447
ISOLATE 67	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (2)	2019	31481447
ISOLATE 68	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (2), Micafungin (0.5)	2019	31481447
ISOLATE 69	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 7	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (16), Micafungin (4)	2019	31481447
ISOLATE 70	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 71	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (4)	2019	31481447
ISOLATE 72	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (16), Micafungin (4)	2019	31481447
ISOLATE 73	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 74	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 75	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2019	31481447
ISOLATE 76	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	31481447
ISOLATE 80	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663P	Single substitution Single substitution	Not available Not available	Not available Not available	Not available Not available		Anidulafungin (1), Caspofungin (8), Micafungin (1)	2019	31481447
ISOLATE 82	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (4), Micafungin (2)	2019	31481447
ISOLATE 84	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (8), Micafungin (2)	2019	31481447
ISOLATE 85	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 86	C. glabrata	Clinical isolate	FKS2	del658F	Deletion	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (2)	2019	31481447
ISOLATE 87	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (1), Caspofungin (4), Micafungin (1)	2019	31481447
ISOLATE 88	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (>16), Micafungin (1)	2019	31481447
ISOLATE 9	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (4), Caspofungin (>16), Micafungin (4)	2019	31481447
ISOLATE 90	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Not available	Not available	Not available	Structure not available	Anidulafungin (2), Caspofungin (4), Micafungin (1)	2019	31481447
Alberta 2014	C. glabrata	Clinical isolate	FKS1 FKS2	S629P S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (2)	2019	31505645
Alberta 2016	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5)	2019	31505645
British Columbia 2013-1	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4)	2019	31505645
British Columbia 2013-2	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5)	2019	31505645
Manitoba 2014	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (1)	2019	31505645
Brazil	C. tropicalis	Clinical isolate	FKS1	F650S	Single substitution	C5M4K6	1640	Model	Mismatch residue	Anidulafungin (1), Caspofungin (2), Micafungin (1)	2020	31520783
CA, USA	C. parapsilosis	Clinical isolate	FKS2 ERG11	Y657del, F658Y Y132F	Complex Single substitution	Q6FMZ3 C7EXA5	1897 522	Model AF-C7EXA5-F1		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25) Fluconazole (32)	2020	31520783
CO, USA	C. tropicalis	Clinical isolate	FKS2 FKS1	F659S S654P	Single substitution Single substitution	Q6FMZ3 C5M4K6	1897 1640	Model Model		Anidulafungin (1), Caspofungin (1), Micafungin (0.25) Anidulafungin (1), Caspofungin (>8), Micafungin (2)	2020	31520783
Czech Republic	C. tropicalis	Clinical isolate	MDR1	E133D	Single substitution	C5MAA0	552	AF-C5MAA0-F1		Fluconazole (16), Voriconazole (1)	2020	31520783
France	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (0.5), Micafungin (0.5)	2020	31520783
France-2016	C. tropicalis	Clinical isolate	MDR1	V76A	Single substitution	C5MAA0	552	AF-C5MAA0-F1		Fluconazole (8)	2020	31520783
France-2017	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	31520783
IN, USA	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	31520783
Ireland	C. parapsilosis	Clinical isolate	ERG11 MDR1	R398I I396V	Single substitution Single substitution	C7EXA5 G8B987	522 558	AF-C7EXA5-F1 AF-G8B987-F1		Fluconazole (8)	2020	31520783
Ireland1	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Caspofungin (1), Micafungin (1)	2020	31520783
Ireland2	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2020	31520783
Ireland3	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Caspofungin (2), Micafungin (0.5)	2020	31520783
Italy	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Caspofungin (4), Micafungin (2)	2020	31520783
Italy-2016-1	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	31520783
Italy-2016-2	C. parapsilosis	Clinical isolate	CDR1 ERG11 MDR1	S79N Y132F, R398I I396V	Single substitution Double substitution Single substitution	G8BJB0 C7EXA5 G8B987	1504 522 558	Model AF-C7EXA5-F1 AF-G8B987-F1		Fluconazole (128), Voriconazole (1)	2020	31520783
Italy-2016-2017	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32-64)	2020	31520783
Italy-2017-1	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2020	31520783
Italy-2017-2	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2020	31520783
Mexico	C. glabrata	Clinical isolate	FKS1	S625S	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Anidulafungin (0.5)	2020	31520783
NY, USA	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2020	31520783
Spain1	C. glabrata	Clinical isolate	FKS2	Y657del, F658Y	Complex	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25)	2020	31520783
Spain2	C. glabrata	Clinical isolate	FKS2	Y657del, F658Y	Complex	Q6FMZ3	1897	Model		Anidulafungin (1), Caspofungin (0.25), Micafungin (0.25)	2020	31520783
Thailand-2016-1	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	Q58J66	528	AF-Q58J66-F1		Fluconazole (32), Voriconazole (1)	2020	31520783
Thailand-2016-2	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	Q58J66	528	AF-Q58J66-F1		Fluconazole (64), Voriconazole (4)	2020	31520783
Thailand-2017	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	Q58J66	528	AF-Q58J66-F1		Fluconazole (32), Voriconazole (1)	2020	31520783
Turkey	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Caspofungin (1), Micafungin (1)	2020	31520783
TX, USA	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2020	31520783
VA, USA	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2020	31520783
WA, USA	C. glabrata	Clinical isolate	FKS1 FKS2	S629P R665G	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2020	31520783
Cg	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Fluconazole (>256), Caspofungin (16), Anidulafungin (4), Micafungin (2), Voriconazole (16), Posaconazole (>8), Itraconazole (>16), Amphotericin B (1)	2019	31545778
ca01	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256), Caspofungin (≥8), Amphotericin B (2)	2019	31600556
ca02	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Amphotericin B (2)	2019	31600556
ca03	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256), Amphotericin B (2)	2019	31600556
ca04	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2019	31600556
ca06	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2019	31600556
C. albicans 90028 strain 4.15	C. albicans	Laboratory strain	GWT1	V162A	Single substitution	Q873N2	485	AF-Q873N2-F1		Manogepix (0.25)	2019	31611349
C. glabrata 2001 strain 5.1	C. glabrata	Laboratory strain	GWT1	V163A	Single substitution	Q6FLH2	486	AF-Q6FLH2-F1		Manogepix (1)	2019	31611349
C. glabrata 2001 strain 5.2	C. glabrata	Laboratory strain	GWT1	V163A	Single substitution	Q6FLH2	486	AF-Q6FLH2-F1		Manogepix (1)	2019	31611349
C. glabrata 2001 strain 5.3	C. glabrata	Laboratory strain	GWT1	V163A	Single substitution	Q6FLH2	486	AF-Q6FLH2-F1		Manogepix (1)	2019	31611349
C. glabrata 2001 strain 5.4	C. glabrata	Laboratory strain	GWT1	V163A	Single substitution	Q6FLH2	486	AF-Q6FLH2-F1		Manogepix (1)	2019	31611349
C. glabrata 2001 strain RNP1	C. glabrata	Laboratory strain	GWT1	V163A	Single substitution	Q6FLH2	486	AF-Q6FLH2-F1		Manogepix (1)	2019	31611349
ISOLATE51	C. albicans	Clinical isolate	MRR2	A459T, S480P	Double substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE52	C. albicans	Clinical isolate	MRR2	H31Y	Single substitution	A0A411I718	710	AF-A0A411I718-F1		Fluconazole (64)	2020	31705810
ISOLATE54	C. albicans	Clinical isolate	MRR2	T145A, S165N	Double substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE57	C. albicans	Clinical isolate	MRR2	T386I	Single substitution	A0A411I718	710	AF-A0A411I718-F1		Fluconazole (64)	2020	31705810
ISOLATE58	C. albicans	Clinical isolate	MRR2	A459T, S480P	Double substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE59	C. albicans	Clinical isolate	MRR2	L144V, T145A, S165N, S480P	Multiple substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE66	C. albicans	Clinical isolate	MRR2	S165N, A459T	Double substitution	A0A411I718	710	AF-A0A411I718-F1		Fluconazole (64)	2020	31705810
ISOLATE67	C. albicans	Clinical isolate	MRR2	S165N, A459T	Double substitution	A0A411I718	710	AF-A0A411I718-F1		Fluconazole (64)	2020	31705810
ISOLATE68	C. albicans	Clinical isolate	MRR2	T145A, S165N	Double substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE69	C. albicans	Clinical isolate	MRR2	L144V, T145A, S165N	Multiple substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE70	C. albicans	Clinical isolate	MRR2	L144V, T145A, S165N, A459T, S480P	Multiple substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE72	C. albicans	Clinical isolate	MRR2	T386I	Single substitution	A0A411I718	710	AF-A0A411I718-F1		Fluconazole (64)	2020	31705810
ISOLATE73	C. albicans	Clinical isolate	MRR2	T83A, T145A, S165N, S480P	Multiple substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
ISOLATE74	C. albicans	Clinical isolate	MRR2	T145A	Single substitution	A0A411I718	710	AF-A0A411I718-F1	Mismatch residue	Fluconazole (64)	2020	31705810
CRISPR-31	C. glabrata	Laboratory strain	FKS2	E655K	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.25), Micafungin (0.25), Anidulafungin (0.25)	2019	31711370
fks1del/Fks2-E655K	C. glabrata	Laboratory strain	FKS2	E655K	Single substitution	Q6FMZ3	1897	Model		Caspofungin (8), Micafungin (16), Anidulafungin (8)	2019	31711370
L74	C. glabrata	Clinical isolate	FKS1 FKS2	W508stop E655K	Stop Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (16), Micafungin (16), Anidulafungin (8)	2019	31711370
isolate 28	C. albicans	Clinical isolate	ERG3	W219C	Single substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (64), Itraconazole (16), Voriconazole (8)	2019	31762516
isolate 6	C. albicans	Clinical isolate	ERG3	R352H	Single substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (64), Itraconazole (4), Voriconazole (8)	2019	31762516
isolate 89	C. albicans	Clinical isolate	ERG3	W219C	Single substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (64), Itraconazole (1), Voriconazole (16)	2019	31762516
CK	C. krusei	Clinical isolate	FKS1	L701M	Single substitution	Q4U2W2	1885	Model		Anidulafungin (2), Micafungin (1)	2020	31782486
113-2BC	C. tropicalis	Clinical isolate	UPC2	T241A	Single substitution	C5MAR7	782	AF-C5MAR7-F1		Fluconazole (8)	2020	31828316
262E	C. tropicalis	Clinical isolate	TAC1 UPC2	R47Q, N164I Q340H, T381S	Double substitution Double substitution	C5MGV3 C5MAR7	943 782	AF-C5MGV3-F1 AF-C5MAR7-F1		Fluconazole (64), Voriconazole (4), Itraconazole (16)	2020	31828316
527E	C. tropicalis	Clinical isolate	MRR1 TAC1	T255P R47Q, N164I	Single substitution Double substitution	C5M9V7 C5MGV3	1150 943	AF-C5M9V7-F1 AF-C5MGV3-F1		Fluconazole (8), Voriconazole (1)	2020	31828316
99-BC	C. tropicalis	Clinical isolate	MRR1	A647S	Single substitution	C5M9V7	1150	AF-C5M9V7-F1		Fluconazole (8), Voriconazole (1)	2020	31828316
CEC4503	C. albicans	Clinical isolate	ERG11 TAC1	D9V, R157K H263Y, H839Y, C858Y	Double substitution Multiple substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (>256), Itraconazole (>32), Voriconazole (>2)	2020	31923309
CEC4504	C. albicans	Clinical isolate	ERG11 TAC1	R157K H263Y, H839Y, C858Y	Single substitution Multiple substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (24), Itraconazole (4)	2020	31923309
CEC4515	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y132H H263Y, P971S G648D	Single substitution Double substitution Single substitution	P10613 A0A1D8PN96 Q59QC7	528 981 712	5V5Z AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>256), Itraconazole (>32), Voriconazole (>32)	2020	31923309
CEC4516	C. albicans	Clinical isolate	ERG11 TAC1	Y132H H263Y, P971S	Single substitution Double substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (>256), Itraconazole (>32), Voriconazole (>32)	2020	31923309
CEC4521	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y132H, R467I H263Y, P971S D654N	Double substitution Double substitution Single substitution	P10613 A0A1D8PN96 Q59QC7	528 981 712	5V5Z AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>256), Itraconazole (>12), Voriconazole (>4)	2020	31923309
CEC4522	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y132H, R467I H263Y, P971S D654N	Double substitution Double substitution Single substitution	P10613 A0A1D8PN96 Q59QC7	528 981 712	5V5Z AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>256), Itraconazole (>32), Voriconazole (>12)	2020	31923309
CEC4524	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y64H, T123I, Y132H, R467I H263Y, P971S D654N	Multiple substitution Double substitution Single substitution	P10613 A0A1D8PN96 Q59QC7	528 981 712	5V5Z AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>256), Itraconazole (>32), Voriconazole (>3), Caspofungin (0.5)	2020	31923309
CEC4527	C. albicans	Clinical isolate	ERG11 TAC1	G448E A736T, N823K, C858Y	Single substitution Multiple substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (>8), Itraconazole (>3)	2020	31923309
CEC718	C. albicans	Clinical isolate	ERG11 TAC1 UPC2	Y132H, P236S, S405F A736T G657D	Multiple substitution Single substitution Single substitution	P10613 A0A1D8PN96 Q59QC7	528 981 712	5V5Z AF-A0A1D8PN96-F1 AF-Q59QC7-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.25), Itraconazole (1)	2020	31923309
CEC723	C. albicans	Clinical isolate	ERG11 TAC1	P30S, S405F A790V	Double substitution Single substitution	P10613 A0A1D8PN96	528 981	5V5Z AF-A0A1D8PN96-F1		Fluconazole (16), Itraconazole (1)	2020	31923309
CK21	C. krusei	Clinical isolate	ERG11	A122S	Single substitution	A9YUC7	528	AF-A9YUC7-F1		Voriconazole (8)	2020	31932372
CK24	C. krusei	Clinical isolate	ERG11	Y140H	Single substitution	A9YUC7	528	AF-A9YUC7-F1		Voriconazole (4)	2020	31932372
CK32	C. krusei	Clinical isolate	ERG11	A122V	Single substitution	A9YUC7	528	AF-A9YUC7-F1		Voriconazole (2), Posaconazole (2)	2020	31932372
CK42	C. krusei	Clinical isolate	ERG11	A364V, Y140H	Double substitution	A9YUC7	528	AF-A9YUC7-F1		Voriconazole (4)	2020	31932372
Ca1	C. auris	Clinical isolate	FKS1 FKS1	S645P S639F	Single substitution Single substitution	A0A1D8PCT0 A0A2H1A4W2	1897 1888	AF-A0A1D8PCT0-F1 Model		Rezafungin (1), Anidulafungin (0.25), Micafungin (2) Rezafungin (16), Anidulafungin (4), Micafungin (>32), Fluconazole (>256)	2020	32015032
Ca2	C. auris	Clinical isolate	FKS1 FKS1	D648Y S639F	Single substitution Single substitution	A0A1D8PCT0 A0A2H1A4W2	1897 1888	AF-A0A1D8PCT0-F1 Model		Rezafungin (0.5), Anidulafungin (0.06), Micafungin (0.125) Rezafungin (16), Anidulafungin (>32), Micafungin (>32), Fluconazole (>256)	2020	32015032
Ca3	C. auris	Clinical isolate	FKS1 FKS1	P1354S S639F	Single substitution Single substitution	A0A1D8PCT0 A0A2H1A4W2	1897 1888	AF-A0A1D8PCT0-F1 Model		Rezafungin (0.5), Anidulafungin (0.06), Micafungin (0.125), Fluconazole (>64) Rezafungin (8), Anidulafungin (>32), Micafungin (>32), Fluconazole (>256)	2020	32015032
Ca4	C. albicans	Clinical isolate	FKS1	P1354S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Micafungin (0.06), Fluconazole (>32)	2020	32015032
Ca5	C. albicans	Clinical isolate	FKS1	P1354S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Micafungin (0.06), Fluconazole (64)	2020	32015032
Ca6	C. albicans	Clinical isolate	FKS1	P1354S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Micafungin (0.06), Fluconazole (>64)	2020	32015032
Ca7	C. albicans	Clinical isolate	FKS1	P1354S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Anidulafungin (0.06), Micafungin (0.06), Fluconazole (64)	2020	32015032
Ca8	C. albicans	Clinical isolate	FKS1	R1361S	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Anidulafungin (0.06), Micafungin (0.125)	2020	32015032
Ca9	C. albicans	Clinical isolate	FKS1	R1361G	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.25), Anidulafungin (0.06), Micafungin (0.125)	2020	32015032
Cd1	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model	Structure not available	Rezafungin (2), Anidulafungin (0.25), Micafungin (2)	2020	32015032
Cd2	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model	Structure not available	Rezafungin (1), Anidulafungin (0.25), Micafungin (2)	2020	32015032
Cg1	C. glabrata	Clinical isolate	FKS1 FKS2	L630Q S663F	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Rezafungin (2), Anidulafungin (1), Micafungin (0.5)	2020	32015032
Cg2	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Rezafungin (2), Anidulafungin (1), Micafungin (0.5)	2020	32015032
Cg3	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Rezafungin (1), Anidulafungin (0.25), Micafungin (0.125)	2020	32015032
Cg4	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.5), Anidulafungin (0.25), Micafungin (0.125)	2020	32015032
Cg5	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.5), Micafungin (0.06)	2020	32015032
Cg6	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.5), Anidulafungin (0.125), Micafungin (0.125)	2020	32015032
Cg7	C. glabrata	Clinical isolate	FKS1 FKS2	Y1429X Y658N	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Rezafungin (0.5), Anidulafungin (0.125), Micafungin (0.06), Fluconazole (>32)	2020	32015032
Cg8	C. glabrata	Clinical isolate	FKS1 FKS2	Y1429X L664Q	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Rezafungin (0.5), Anidulafungin (0.125), Micafungin (0.06), Fluconazole (>32)	2020	32015032
Cg9	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Rezafungin (0.5), Micafungin (0.06), Fluconazole (>64)	2020	32015032
Ck	C. krusei	Clinical isolate	FKS1	S659F	Single substitution	Q4U2W2	1885	Model		Rezafungin (1), Anidulafungin (0.25), Micafungin (4)	2020	32015032
Ct1	C. tropicalis	Clinical isolate	FKS1	F650S	Single substitution	B6S6L8	1904	Model		Rezafungin (1), Anidulafungin (0.25), Micafungin (1)	2020	32015032
Ct2	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Rezafungin (2), Anidulafungin (2), Micafungin (2)	2020	32015032
1015009	C. glabrata	Clinical isolate	FKS2	Y657del, F658Y	Complex	Q6FMZ3	1897	Model		Rezafungin (0.5), Anidulafungin (1), Caspofungin (0.5), Micafungin (0.25)	2020	32015043
1021070	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (1), Anidulafungin (2), Caspofungin (0.5)Micafungin90.5)	2020	32015043
1025460	C. glabrata	Clinical isolate	FKS1 FKS2	S629P R665G	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Rezafungin (0.5), Anidulafungin (1), Caspofungin (0.5), Micafungin (1)	2020	32015043
1026179	C. glabrata	Clinical isolate	FKS2	Y657del, F658Y	Complex	Q6FMZ3	1897	Model		Rezafungin (1), Anidulafungin (10, Caspofungin (0.25), Micafungin (0.25)	2020	32015043
1034513	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (2), Anidulafungin (4), Caspofungin (2), Micafungin (0.5)	2020	32015043
1034514	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.25), Anidulafungin (0.5), Caspofungin (0.12), Micafungin (0.12)	2020	32015043
1051641	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Rezafungin (1), Anidulafungin (1), Caspofungin (1), Micafungin (0.5)	2020	32015043
1078854	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Rezafungin (0.06), Anidulafungin (0.06), Caspofungin (0.06), Micafungin (0.06)	2020	32015043
1078861	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (2), Anidulafungin (2), Caspofungin (1), Micafungin (1)	2020	32015043
1087598	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (2), Anidulafungin (4), Caspofungin (4), Micafungin (4)	2020	32015043
970382	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Rezafungin (0.25), Anidulafungin (0.25), Caspofungin (0.12), Micafungin (0.12)	2020	32015043
970388	C. tropicalis	Clinical isolate	FKS1	S645P	Single substitution	B6S6L8	1904	Model	Mismatch residue	Rezafungin (2), Anidulafungin (1), Caspofungin (>8), Micafungin (2)	2020	32015043
970397	C. glabrata	Clinical isolate	FKS2	P667H	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.12), Anidulafungin (0.25), Caspofungin (0.25), Micafungin (0.12)	2020	32015043
974239	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Rezafungin (0.25), Anidulafungin (0.25), Caspofungin (0.06), Micafungin (0.12)	2020	32015043
974249	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (2), Anidulafungin (20), Caspofungin (10), Micafungin (1)	2020	32015043
977041	C. tropicalis	Clinical isolate	FKS1	F650S	Single substitution	B6S6L8	1904	Model		Rezafungin (1), Anidulafungin (1), Caspofungin (2), Micafungin (1)	2020	32015043
983007	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Rezafungin (0.12), Anidulafungin (0.5), Caspofungin (0.06), Micafungin (0.12)	2020	32015043
984357	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	O13428	1897	Model		Rezafungin (0.25), Anidulafungin (0.12), Caspofungin (1), Micafungin (1)	2020	32015043
985673	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.06), Anidulafungin (0.12), Caspofungin (0.06), Micafungin (0.06)	2020	32015043
997524	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Rezafungin (0.5), Anidulafungin (0.5), Caspofungin (0.25), Micafungin (0.06)	2020	32015043
Index case 1	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1), Caspofungin (4), Micafungin (2), Fluconazole (128)	2020	32024039
Index case 2	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (2), Caspofungin (16), Micafungin (4)	2020	32024039
Ct10	C. tropicalis	Clinical isolate	ERG11	G464S	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2020	32084606
Ct16	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2020	32084606
C. albicans LC191	C. albicans	Laboratory strain	ZCF29	W986L	Single substitution	A0A1D8PRB7	1105	AF-A0A1D8PRB7-F1		Beauvericin (100)	2020	32179530
RPCA14	C. albicans	Clinical isolate	ERG11	A317T	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA30	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA4	C. albicans	Clinical isolate	ERG11	D266D	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1	Mismatch residue	Fluconazole (32)	2020	32219719
RPCA41	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA45	C. albicans	Clinical isolate	ERG11	F145L	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (64)	2020	32219719
RPCA47	C. albicans	Clinical isolate	ERG11	F145L	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA6	C. albicans	Clinical isolate	ERG11	V437I	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA61	C. albicans	Clinical isolate	ERG11	G129R	Single substitution	Q9P4W0	528	AF-Q9P4W0-F1		Fluconazole (>128)	2020	32219719
RPCA9	C. albicans	Clinical isolate	ERG11	Y132C, F145L, A114V	Multiple substitution	Q9P4W0	528	AF-Q9P4W0-F1	Structure not available	Fluconazole (64)	2020	32219719
Kw164/15	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		EUCAST[Micafungin (2)], Etest[Micafungin (0.125), Caspofungin (0.75), Fluconazole (64)]	2020	32277126
Kw2138/17	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		EUCAST[Micafungin (0.25)], Etest[Micafungin (0.25)]	2020	32277126
Kw3554/16	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		EUCAST[Micafungin (1)], ETEST[Micafungin (0.125)]	2020	32277126
Kw3646/15	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		EUCAST[Micafungin (2)], Etest[Micafungin (0.125), Caspofungin (0.75)]	2020	32277126
Kw458/16	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		EUCAST[Micafungin (2)], Etest[Micafungin (0.125), Caspofungin (0.75)]	2020	32277126
Ca1	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Azole	2020	32345637
Ca2	C. auris	Clinical isolate	ERG11	F126L, V125A	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=32)	2020	32345637
Ca3	C. auris	Clinical isolate	FKS1	S639P	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (>=4 )	2020	32345637
Ca4	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (>=4 )	2020	32345637
Ca5	C. auris	Clinical isolate	FKS1	S639Y	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (>=4 )	2020	32345637
G103	C. glabrata	Clinical isolate	FKS2 PDR1	S663P S76P, L98S, T143P, 226-Ins_KLTQAVN-227	Single substitution Complex	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Fluconazole (64), Micafungin (0.125), Anidulafungin (0.25)	2020	32413170
G107	C. glabrata	Clinical isolate	PDR1	S76P, L98S, T143P, F439I, D554E, E590D, P927R	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2020	32413170
G29	C. glabrata	Clinical isolate	FKS1 PDR1	S629P S76P, L98S, T143P, E590D	Single substitution Multiple substitution	Q6FTN8 Q6FXU7	1863 1107	Model AF-Q6FXU7-F1		Anidulafungin (0.064)	2020	32413170
G51	C. glabrata	Clinical isolate	PDR1	S76P, L98S, T143P	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32)	2020	32413170
G53	C. glabrata	Clinical isolate	FKS2 PDR1	S663P L98S, D243N	Single substitution Double substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Fluconazole (64), Anidulafungin (0.064)	2020	32413170
G55	C. glabrata	Clinical isolate	PDR1	S76P, L98S, T143P, N768I	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2020	32413170
G6	C. glabrata	Clinical isolate	PDR1	S76P, L98S, T143P, P695R	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64)	2020	32413170
G98	C. glabrata	Clinical isolate	PDR1	L98S, D243N, L281V, E590D	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (32)	2020	32413170
wild 2	C. glabrata	Clinical isolate	PDR1	L280F	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Voriconazole (0.5), Itraconazole (0.5)	2020	32563123
wild 4	C. glabrata	Clinical isolate	PDR1	L344S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (0.5), Itraconazole (0.5)	2020	32563123
wild 6	C. glabrata	Clinical isolate	PDR1	G346D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64), Voriconazole (1), Itraconazole (2)	2020	32563123
52015	C. glabrata	Clinical isolate	PDR1	Y1094H	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (>64)	2020	32571826
56530	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
60089	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (1), Caspofungin (8)	2020	32571826
61000	C. glabrata	Clinical isolate	PDR1	E555D	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
61169	C. glabrata	Clinical isolate	PDR1	G493D	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
61186	C. glabrata	Clinical isolate	PDR1	G493D	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
61193	C. glabrata	Clinical isolate	PDR1	W1098C	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
61756	C. glabrata	Clinical isolate	PDR1	T370I	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5), Fluconazole (>64)	2020	32571826
64679	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2020	32571826
64680	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2020	32571826
64683	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2020	32571826
64684	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2020	32571826
64685	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2020	32571826
64686	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Caspofungin (2)	2020	32571826
64687	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2020	32571826
64688	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2020	32571826
64689	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (2), Caspofungin (8)	2020	32571826
64903	C. glabrata	Clinical isolate	PDR1	L139I	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
64904	C. glabrata	Clinical isolate	PDR1	L139I	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
64905	C. glabrata	Clinical isolate	PDR1	L139I	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Caspofungin (0.5)	2020	32571826
Episode 1st	C. glabrata	Clinical isolate	FKS1 FKS1 FKS1 FKS2 FKS2	R1361G S645P S645P F659stop S663P	Single substitution Single substitution Single substitution Stop Single substitution	O13428 O13428 O13428 Q6FMZ3 Q6FMZ3	1897 1897 1897 1897 1897	Model Model Model Model Model		Anidulafungin (2), Micafungin (1), Caspofungin (1) Anidulafungin (2), Micafungin (4), Caspofungin (8) Anidulafungin (2), Micafungin (4), Caspofungin (>16) Anidulafungin (4), Micafungin (4), Caspofungin (16)	2020	32661647
Episode 2nd	C. glabrata	Clinical isolate	FKS1 FKS2 FKS2	S645P S629P S663P	Single substitution Single substitution Single substitution	O13428 Q6FMZ3 Q6FMZ3	1897 1897 1897	Model Model Model		Anidulafungin (2), Micafungin (2), Caspofungin (4) Micafungin (4), Caspofungin (16) Anidulafungin (4), Micafungin (4), Caspofungin (>16)	2020	32661647
101FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I, A793S	Double substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32) Voriconazole (1)	2020	32690638
106FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R A793S	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
107FS	C. parapsilosis	Clinical isolate	ERG11 TAC1	Y132F, K143R A21V	Double substitution Single substitution	C7EXA5 G8B8R4	522 347	AF-C7EXA5-F1 AF-G8B8R4-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
108FS	C. parapsilosis	Clinical isolate	ERG11 TAC1	Y132F A21V	Single substitution Single substitution	C7EXA5 G8B8R4	522 347	AF-C7EXA5-F1 AF-G8B8R4-F1		Fluconazole (8)	2020	32690638
10P	C. parapsilosis	Clinical isolate	ERG11 UPC2	G458S, T519A A793S	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
112FS	C. parapsilosis	Clinical isolate	ERG11 TAC1 UPC2	K143R A21V A793S	Single substitution Single substitution Single substitution	C7EXA5 G8B8R4 G8BCU0	522 347 847	AF-C7EXA5-F1 AF-G8B8R4-F1 AF-G8BCU0-F1		Fluconazole (>32)	2020	32690638
15FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R A793S	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (2)	2020	32690638
15P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F A793S	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
19P	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2020	32690638
1R	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (2)	2020	32690638
22R	C. parapsilosis	Clinical isolate	UPC2	G342S	Single substitution	G8BCU0	847	AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
25P	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	Y132F G427V P150H	Single substitution Single substitution Single substitution	C7EXA5 G8BAV4 G8B8R4	522 1128 347	AF-C7EXA5-F1 AF-G8BAV4-F1 AF-G8B8R4-F1		Fluconazole (8)	2020	32690638
26R	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	Q250K, R398I, G458S P295L, Q1074stop L390I	Multiple substitution Complex Single substitution	C7EXA5 G8BAV4 G8B8R4	522 1128 347	AF-C7EXA5-F1 AF-G8BAV4-F1 AF-G8B8R4-F1		Fluconazole (16)	2020	32690638
2P	C. parapsilosis	Clinical isolate	ERG11 TAC1 UPC2	Y132F L578M A793S	Single substitution Single substitution Single substitution	C7EXA5 G8B8R4 G8BCU0	522 347 847	AF-C7EXA5-F1 AF-G8B8R4-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
30P	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2020	32690638
30R	C. parapsilosis	Clinical isolate	ERG11	Y132F, K143R	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
31P	C. parapsilosis	Clinical isolate	ERG11	G458S	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
34R	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I G490R	Single substitution Single substitution	C7EXA5 G8B8R4	522 347	AF-C7EXA5-F1 AF-G8B8R4-F1		Fluconazole (32)	2020	32690638
35P	C. parapsilosis	Clinical isolate	ERG11	Y132F, G307A	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (2)	2020	32690638
36P	C. parapsilosis	Clinical isolate	ERG11	G458S	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2020	32690638
37P	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32)	2020	32690638
37R	C. parapsilosis	Clinical isolate	ERG11	R398I	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32)	2020	32690638
38R	C. parapsilosis	Clinical isolate	ERG11 TAC1	R398I G490R, S760R, A761G	Single substitution Multiple substitution	C7EXA5 G8B8R4	522 347	AF-C7EXA5-F1 AF-G8B8R4-F1		Fluconazole (>32)	2020	32690638
3P	C. parapsilosis	Clinical isolate	ERG11 TAC1 UPC2	Y132F N7Y, L578M A793S	Single substitution Double substitution Single substitution	C7EXA5 G8B8R4 G8BCU0	522 347 847	AF-C7EXA5-F1 AF-G8B8R4-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
40P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F L38I	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
41P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F A793S	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
41R	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (32)	2020	32690638
42P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F E7stop	Single substitution Stop	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
43P	C. parapsilosis	Clinical isolate	ERG11	Y132F, K143R	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
43R	C. parapsilosis	Clinical isolate	ERG11 UPC2	K143R L38I	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
45P	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2020	32690638
47P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F P45H	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
49P	C. parapsilosis	Clinical isolate	ERG11	Y132F, G307A	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (2)	2020	32690638
50P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F P45H, A793S	Single substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
50R	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
54P	C. parapsilosis	Clinical isolate	ERG11 TAC1	Y132F, K143R Q965K, M966V	Double substitution Double substitution	C7EXA5 G8B8R4	522 347	AF-C7EXA5-F1 AF-G8B8R4-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
55P	C. parapsilosis	Clinical isolate	MRR1	L419F	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (8)	2020	32690638
56FS	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
59FS	C. parapsilosis	Clinical isolate	ERG11	Y132F, K143R	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
59P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F Q372H	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (8)	2020	32690638
5FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F L38I, A793S	Single substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32)	2020	32690638
60P	C. parapsilosis	Clinical isolate	ERG11 MRR1 TAC1	Y132F Q1027R D603V, P803L	Single substitution Single substitution Double substitution	C7EXA5 G8BAV4 G8B8R4	522 1128 347	AF-C7EXA5-F1 AF-G8BAV4-F1 AF-G8B8R4-F1		Fluconazole (8)	2020	32690638
65P	C. parapsilosis	Clinical isolate	ERG11 UPC2	G458S Q371H	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
67FS	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	32690638
68FS	C. parapsilosis	Clinical isolate	ERG11	Y132F, K143R	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	32690638
69FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I, A793S	Double substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32) Voriconazole (1)	2020	32690638
6FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R L38I, A793S	Double substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
75P	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F Q1027R	Single substitution Single substitution	C7EXA5 G8BAV4	522 1128	AF-C7EXA5-F1 AF-G8BAV4-F1		Fluconazole (8)	2020	32690638
77P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, G307A L38I, Q371H	Double substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (16)	2020	32690638
7P	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F, K143R L926stop	Double substitution Stop	C7EXA5 G8BAV4	522 1128	AF-C7EXA5-F1 AF-G8BAV4-F1		Fluconazole (>32)	2020	32690638
81P	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F, K143R G472V	Double substitution Single substitution	C7EXA5 G8BAV4	522 1128	AF-C7EXA5-F1 AF-G8BAV4-F1		Fluconazole (>32)	2020	32690638
87P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F, K143R P45H	Double substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
91P	C. parapsilosis	Clinical isolate	ERG11	G458S	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2020	32690638
94FS	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F L38I, A793S	Single substitution Double substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32)	2020	32690638
96P	C. parapsilosis	Clinical isolate	ERG11	Y132F, K143R	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>32), Voriconazole (1)	2020	32690638
97FS	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2020	32690638
9P	C. parapsilosis	Clinical isolate	ERG11 UPC2	Y132F A793S	Single substitution Single substitution	C7EXA5 G8BCU0	522 847	AF-C7EXA5-F1 AF-G8BCU0-F1		Fluconazole (>32), Voriconazole (2)	2020	32690638
CG Isolate 2	C. glabrata	Clinical isolate	FKS2	F659Y, I1333F	Double substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (2), Caspofungin (8), Micafungin (8), Fluconazole (8)	2020	32899996
FMR 14602	C. tropicalis	Clinical isolate	ERG11	D448G	Single substitution	P14263	528	AF-P14263-F1	Mismatch residue	MIC90[Voriconazole (16), Posaconazole (0.25), Itraconazole (8)]	2020	33077654
FMR 14603	C. tropicalis	Clinical isolate	ERG11	D445V	Single substitution	P14263	528	AF-P14263-F1	Mismatch residue	MIC90[Voriconazole (2), Posaconazole (0.5), Itraconazole (2)]	2020	33077654
FMR 8898	C. tropicalis	Clinical isolate	ERG11	L403-V528del	Deletion	P14263	528	AF-P14263-F1	Structure not available	MIC90[Voriconazole (16), Posaconazole (>16), Itraconazole (16)]	2020	33077654
123	C. tropicalis	Clinical isolate	ERG11	R245K	Double substitution	P14263	528	AF-P14263-F1	Structure not available	Fluconazole (256)	2020	33123116
30	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (64), Voriconazole (2)	2020	33123116
31	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (32), Voriconazole (1)	2020	33123116
MICR1	C. parapsilosis	Clinical isolate	FKS1	R658G	Single substitution	A9YLC3	1909	Model		Micafungin (>8)	2021	33175162
MICR2	C. parapsilosis	Clinical isolate	ERG11 FKS1	Y132F, K143R R658G	Double substitution Single substitution	G8B9T3 A9YLC3	522 1909	AF-G8B9T3-F1 Model		Micafungin (>8), Fluconazole (32)	2021	33175162
MICR3	C. parapsilosis	Clinical isolate	ERG11 FKS1	Y132F, K143R R658G	Double substitution Single substitution	G8B9T3 A9YLC3	522 1909	AF-G8B9T3-F1 Model		Micafungin (>8), Fluconazole (32)	2021	33175162
MICR4	C. parapsilosis	Clinical isolate	ERG11 FKS1	Y132F, K143R R658G	Double substitution Single substitution	G8B9T3 A9YLC3	522 1909	AF-G8B9T3-F1 Model		Micafungin (>8), Fluconazole (32)	2021	33175162
All isolates	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (64), Voriconazole (4), Itraconazole (4), Posaconazole (2)	2020	33233388
PATIENT C18	C. auris	Clinical isolate	ERG11 FKS1	Y132F F635del	Single substitution Deletion	A0A2H1A309 A0A0L0P0U2	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (64), Voriconazole (4), Itraconazole (4), Posaconazole (2), Echinocandin	2020	33233388
PATIENT C5	C. auris	Clinical isolate	ERG11 FKS1	Y132F, K143R S639F	Double substitution Single substitution	A0A2H1A309 A0A0L0P0U2	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (64), Voriconazole (4), Itraconazole (4), Posaconazole (2), Echinocandin	2020	33233388
isoalte 78	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2021	33305313
isolate 23	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32), Voriconazole (2)	2021	33305313
isolate 44	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16), Voriconazole (0.5)	2021	33305313
isolate 47	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32), Voriconazole (0.5)	2021	33305313
isolate 67	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2021	33305313
isolate 68	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16)	2021	33305313
isolate 76	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16), Voriconazole (1)	2021	33305313
CA1	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (16)	2020	33396402
CA3	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (32)	2020	33396402
CA4	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (32)	2020	33396402
CA5	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (32)	2020	33396402
CA7	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (32)	2020	33396402
CA8	C. auris	Clinical isolate	ERG11	F132Y, K143R	Double substitution	A0A2H4QC40	524	AF-A0A2H4QC40-F1		Fluconazole (8)	2020	33396402
NCCPF ID 420189	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128), Voriconazole (4)	2021	33439909
NCCPF ID 420227	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2021	33439909
NCCPF ID 420232	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2021	33439909
NCCPF ID 420233	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32), Voriconazole (1)	2021	33439909
NCCPF ID 420234	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64), Voriconazole (1)	2021	33439909
NCCPF ID 420235	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2021	33439909
NCCPF ID 420236	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2021	33439909
NCCPF ID 420237	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64), Voriconazole (1)	2021	33439909
NCCPF ID 420238	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256), Voriconazole (16), Itraconazole (16), Posaconazole (2)	2021	33439909
NCCPF ID 420239	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256), Voriconazole (16), Itraconazole (16)	2021	33439909
NCCPF ID 420245	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128), Voriconazole (4)	2021	33439909
NCCPF ID 420247	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128), Voriconazole (4)	2021	33439909
CA-170	C. albicans	Clinical isolate	ERG3	V351A	Single substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (>64)	2021	33468487
CA-276	C. albicans	Clinical isolate	ERG11 ERG3	A114S, Y257H, G464S V351A	Multiple substitution Single substitution	Q9P4W0 Q59VG6	528 386	AF-Q9P4W0-F1 AF-Q59VG6-F1		Fluconazole (8)	2021	33468487
CA-313	C. albicans	Clinical isolate	ERG3	T291I, V351A	Double substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (>64)	2021	33468487
CA-413	C. albicans	Clinical isolate	ERG3	V351A	Single substitution	Q59VG6	386	AF-Q59VG6-F1	Mismatch residue	Fluconazole (>64)	2021	33468487
CG-024	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.125)	2021	33468487
CT-033	C. tropicalis	Clinical isolate	FKS1	R656G	Single substitution	B6S6L8	1904	Model		Micafungin (0.125)	2021	33468487
CT-165	C. tropicalis	Clinical isolate	FKS1	S654F	Single substitution	B6S6L8	1904	Model		Micafungin (2), Anidulafungin (2)	2021	33468487
IV.3	C. auris	Laboratory strain	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A411K953 A0A894YV30	524 868	AF-A0A411K953-F1 AF-A0A894YV30-F1		Fluconazole (128)	2023	33619054
IV.4	C. auris	Laboratory strain	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A411K953 A0A894YV30	524 868	AF-A0A411K953-F1 AF-A0A894YV30-F1		Fluconazole (128)	2023	33619054
IV.5	C. auris	Laboratory strain	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A411K953 A0A894YV30	524 868	AF-A0A411K953-F1 AF-A0A894YV30-F1		Fluconazole (128)	2023	33619054
IV.6	C. auris	Laboratory strain	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A411K953 A0A894YV30	524 868	AF-A0A411K953-F1 AF-A0A894YV30-F1		Fluconazole (128)	2023	33619054
L09	C. lusitaniae	Clinical isolate	MRR1	Y813N	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16)	2021	33785623
L10	C. lusitaniae	Clinical isolate	MRR1	Y813N	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (8-16)	2021	33785623
L11	C. lusitaniae	Clinical isolate	MRR1	R1066S, K912N	Double substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (8)	2021	33785623
L12	C. lusitaniae	Clinical isolate	MRR1	R1066S, Y1061stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (8)	2021	33785623
L13	C. lusitaniae	Clinical isolate	MRR1	I599T	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (0.5-1)	2021	33785623
L14	C. lusitaniae	Clinical isolate	MRR1	L1191H, Q1197stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (1)	2021	33785623
L15	C. lusitaniae	Clinical isolate	MRR1	Y1126N, P1174P	Double substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (0.5-1)	2021	33785623
L16	C. lusitaniae	Clinical isolate	MRR1	R1066S, G1231stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (8)	2021	33785623
L17	C. lusitaniae	Clinical isolate	MRR1	H467L	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16)	2021	33785623
S18	C. lusitaniae	Clinical isolate	MRR1	H467L	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16)	2021	33785623
S19	C. lusitaniae	Clinical isolate	MRR1	Y813N	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16)	2021	33785623
S20	C. lusitaniae	Clinical isolate	MRR1	H467L	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16)	2021	33785623
S21	C. lusitaniae	Clinical isolate	MRR1	L1191H, Q1197stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (0.5-1)	2021	33785623
U02	C. lusitaniae	Clinical isolate	MRR1	Y1126N, P1174P	Double substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (1-2)	2021	33785623
U03	C. lusitaniae	Clinical isolate	MRR1	R1066S, A550V	Double substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (2-4)	2021	33785623
U04	C. lusitaniae	Clinical isolate	MRR1	Y813C	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16-32)	2021	33785623
U05	C. lusitaniae	Clinical isolate	MRR1	L1191H, Q1197stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (0.5-1)	2021	33785623
U06	C. lusitaniae	Clinical isolate	MRR1	Y1126N, S359stop	Complex	C4XX69	1392	Model	Mismatch residue	Fluconazole (8-16)	2021	33785623
U07	C. lusitaniae	Clinical isolate	MRR1	Y1126N, P1174P	Double substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (0.5-1)	2021	33785623
U08	C. lusitaniae	Clinical isolate	MRR1	E722K	Single substitution	C4XX69	1392	Model	Mismatch residue	Fluconazole (16-32)	2021	33785623
CAS12	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2021	33807036
CAS14	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32), Amphotericin B (2)	2021	33807036
CAS16	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (8), Amphotericin B (2)	2021	33807036
CAS17	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Amphotericin B (2)	2021	33807036
CAS20	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256), Amphotericin B (4)	2021	33807036
CAS20044	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Amphotericin B (2)	2021	33807036
CAS25	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Itraconazole (16), Posaconazole (8), Voriconazole (8), Amphotericin B (2)	2021	33807036
CAS27	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (64), Amphotericin B (2)	2021	33807036
CAS33	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (8), Amphotericin B (2)	2021	33807036
CAS34	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Amphotericin B (2)	2021	33807036
CAS41	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32), Amphotericin B (2)	2021	33807036
10-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
101-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
105-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
108-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
109-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
11-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
110-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
115-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
116-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
118-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
119-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
11E	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
122-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
14-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
16-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
17D	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
17E	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
19-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
2-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
22-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
25-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
26-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
27-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
3-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
31-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
32-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
33-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
34-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
36-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
38-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
4-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
41-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
45-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
46-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2021	33808442
47-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
49-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
51-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
52-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
53-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
55-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
57-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
59-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
62-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
63-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
64-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
70-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
71-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
73-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
75-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
77-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
78-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
79-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
80-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
81-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
82-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
85-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
87-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
9-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
90-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
91-26/19	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
C935	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
C936	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
CBL1017	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
CBL1028	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
P10/9S	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64), Voriconazole (>4)	2021	33808442
A21(C.auris B11220)	C. auris	Laboratory strain	ERG11 ERG3	E429stop W182stop	Stop Stop	A0A2H1A309 A0A2H0ZNC5	524 363	AF-A0A2H1A309-F1 AF-A0A2H0ZNC5-F1		Fluconazole (>64), Amphotericin B (2)	2021	33820824
A27	C. auris	Laboratory strain	ERG11 ERG3 MEC3	E429stop W182stop A272V	Stop Stop Single substitution	A0A2H1A309 A0A2H0ZNC5 A0A2H0ZSE9	524 363 320	AF-A0A2H1A309-F1 AF-A0A2H0ZNC5-F1 AF-A0A2H0ZSE9-F1		Fluconazole (>64), Amphotericin B (4)	2021	33820824
A29	C. auris	Laboratory strain	ERG11 ERG3 FLO8 MEC3	E429stop W182stop Q384stop A272V	Stop Stop Stop Single substitution	A0A2H1A309 A0A2H0ZNC5 A0A2H1A8R7 A0A2H0ZSE9	524 363 537 320	AF-A0A2H1A309-F1 AF-A0A2H0ZNC5-F1 AF-A0A2H1A8R7-F1 AF-A0A2H0ZSE9-F1		Fluconazole (>64), Amphotericin B (4)	2021	33820824
C15	C. auris	Laboratory strain	FKS1	F365L, M690I	Double substitution	A0A2H1A4W2	1888	Model	Mismatch residue	Caspofungin (64)	2021	33820824
C20	C. auris	Laboratory strain	ERG3 FKS1	L207I F365L, M690I	Single substitution Double substitution	A0A2H0ZNC5 A0A2H1A4W2	363 1888	AF-A0A2H0ZNC5-F1 Model		Caspofungin (>64)	2021	33820824
C3	C. auris	Laboratory strain	FKS1	F635L	Single substitution	A0A2H1A4W2	1888	Model	Structure not available	Caspofungin (64)	2021	33820824
CF16	C. auris	Laboratory strain	ERG3 FKS1	L207I F365L, M690I	Single substitution Double substitution	A0A2H0ZNC5 A0A2H1A4W2	363 1888	AF-A0A2H0ZNC5-F1 Model		Fluconazole (16), Caspofungin (64)	2021	33820824
F13	C. auris	Laboratory strain	TAC1	S191fs	Frameshift	A0A2H0ZHW2	868	AF-A0A2H0ZHW2-F1		Fluconazole (32)	2021	33820824
F30	C. auris	Laboratory strain	TAC1	S191fs	Frameshift	A0A2H0ZHW2	868	AF-A0A2H0ZHW2-F1		Fluconazole (>64), Amphotericin B (1)	2021	33820824
FC16	C. auris	Laboratory strain	CIS2 FKS1 TAC1	A27T F635L S191fs	Single substitution Single substitution Frameshift	A0A2H0ZLW4 A0A2H1A4W2 A0A2H0ZHW2	625 1888 868	AF-A0A2H0ZLW4-F1 Model AF-A0A2H0ZHW2-F1		Fluconazole (>64), Caspofungin (>64),	2021	33820824
FC17	C. auris	Laboratory strain	CIS2 FKS1 PEA2 TAC1	A27T F635L D367V S191fs	Single substitution Single substitution Single substitution Frameshift	A0A2H0ZLW4 A0A2H1A4W2 A0A2H1A1Q3 A0A2H0ZHW2	625 1888 540 868	AF-A0A2H0ZLW4-F1 Model AF-A0A2H1A1Q3-F1 AF-A0A2H0ZHW2-F1		Fluconazole (>64), Caspofungin (>64), Amphotericin B (1)	2021	33820824
PATIENT1-S1	C. parapsilosis	Clinical isolate	ERG11	G458S	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32), Voriconazole (1)	2021	33934400
PATIENT2-S2	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F R405K	Single substitution Single substitution	C7EXA5 A0A0K0NQY2	522 1128	AF-C7EXA5-F1 AF-A0A2H1A1Q3-F1		Fluconazole (16), Voriconazole (0.25), Posaconazole (0.125)	2021	33934400
PATIENT3-S3	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F R405K	Single substitution Single substitution	C7EXA5 A0A0K0NQY2	522 1128	AF-C7EXA5-F1 AF-A0A2H1A1Q3-F1		Fluconazole (64), Voriconazole (0.25)	2021	33934400
PATIENT3-S4	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32), Voriconazole (0.125)	2021	33934400
PATIENT4-S1	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16), Voriconazole (0.25)	2021	33934400
CA-18	C. albicans	Clinical isolate	ERG11	T123I	Single substitution	P10613	528	5V5Z		Fluconazole (64), Itraconazole, Voriconazole	2021	33951330
CA-26	C. albicans	Clinical isolate	ERG11	A516P	Single substitution	P10613	528	5V5Z		Fluconazole (64), Itraconazole, Voriconazole	2021	33951330
CA-29	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Itraconazole	2021	33951330
CA-32	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (32)	2021	33951330
CA-40	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (16), Itraconazole, Voriconazole	2021	33951330
CA-56	C. albicans	Clinical isolate	ERG11	K128T, Y132H	Double substitution	P10613	528	5V5Z		Fluconazole (64), Itraconazole, Voriconazole	2021	33951330
CA-9	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Fluconazole (64), Fluconazole, Voriconazole	2021	33951330
n=1 isolates	C. parapsilosis	Clinical isolate	ERG11	G307A, G458S	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64)	2021	33968809
n=17 isolates	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (4-32)	2021	33968809
n=3 isolates	C. parapsilosis	Clinical isolate	ERG11	Y132F, G307A	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>64)	2021	33968809
n=4 isolates	C. parapsilosis	Clinical isolate	ERG11	G458S	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (16->64)	2021	33968809
C12_A109	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU10_A58	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU11_A77	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU12_A79	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU13_A93	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU13_A94	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU14_A96	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU15_A100	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU16_A101	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU16_A102	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU16_A103	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU16_A104	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256), Voriconazole (4)	2021	34027824
NICU2_A13	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU3_A15	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU3_A16	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU3_A17	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU3_A18	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU4_A19	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU4_A20	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256), Voriconazole (4)	2021	34027824
NICU5_A36	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU5_A37	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
NICU6_A41	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU7_A42	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU7_A44	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU8_A43	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU8_A45	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU8_A46	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU8_A47	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU8_A48	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU9_A50	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NICU9_A51	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NSICU1_A24	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
NSICU1_A31	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RI-A112	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RI-A114	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU10_A57	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A62	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A63	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU11_A64	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A74	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A75	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A76	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU11_A81	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU12_A80	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU13_A83	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU13_A85	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU13_A86	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU14_A95	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU15_A105	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU15_A110	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU16_A106	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU16_A107	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU17_A108	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU18_A113	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU19_A115	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU1_A1	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU2_A2	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU2_A4	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256), Voriconazole (4), Itraconazole (1)	2021	34027824
RICU2_A5	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Amphotericin B (2), Fluconazole (>256)	2021	34027824
RICU3_A3	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU4_A10	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU4_A7	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256), Voriconazole (4)	2021	34027824
RICU4_A8	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU5_A12	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU6_A14	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (128)	2021	34027824
RICU7_A22	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU7_A23	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU7_A25	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU7_A29	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU7_A33	C. auris	Clinical isolate	ERG11 FKS1	F126L, I74L S639F	Double substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (8), Micafungin (8), Caspofungin (4)	2021	34027824
RICU7_A34	C. auris	Clinical isolate	ERG11 FKS1	F126L, I74L S639F	Double substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (8), Micafungin (8), Caspofungin (4)	2021	34027824
RICU8_A38	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU8_A39	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU9_A111	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU9_A116	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU9_A52	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU9_A54	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU9_A56	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU9_A59	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
RICU9_A61	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU9_A65	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
RICU9_A82	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
SICU1_A66	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
SICU1_A67	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU1_A68	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU1_A70	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU1_A71	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
SICU1_A72	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (>256)	2021	34027824
SICU2_A89	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU2_A90	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU2_A91	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU2_A97	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
SICU2_A98	C. auris	Clinical isolate	ERG11	F126L, I74L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1	Mismatch residue	Fluconazole (256)	2021	34027824
ISOLATE 10 (SC5314)	C. albicans	Clinical isolate	ERG11	S16V, P68L, D269E	Multiple substitution	P10613	528	5V5Z		Fluconazole	2021	34033880
ISOLATE 7 (SC5314)	C. albicans	Clinical isolate	ERG11	N490T	Single substitution	P10613	528	5V5Z		Fluconazole	2021	34033880
ISOLATE 9 (SC5314)	C. albicans	Clinical isolate	ERG11	Q250S, K252E	Double substitution	P10613	528	5V5Z		Fluconazole	2021	34033880
10262	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2021	34060660
23591	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256)	2021	34060660
31052	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256)	2021	34060660
42372	C. auris	Clinical isolate	ERG11 FKS1	Y132F S639F	Single substitution Single substitution	A0A2H1A309 A0A2H1A4W2	524 1888	AF-A0A2H1A309-F1 Model		Micafungin (8), Fluconazole (32)	2021	34060660
73089	C. auris	Clinical isolate	ERG11 FKS1	Y132F S639F	Single substitution Single substitution	A0A2H1A309 A0A2H1A4W2	524 1888	AF-A0A2H1A309-F1 Model		Anidulafungin (4), Micafungin (8), Fluconazole (16)	2021	34060660
84109	C. glabrata	Clinical isolate	FKS2	D666V, L1303F, V1305I	Multiple substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (0.5), Fluconazole (256)	2021	34060660
87120	C. parapsilosis	Clinical isolate	ERG11	T504S, W244L	Double substitution	G8B9T3	522	AF-G8B9T3-F1		Fluconazole (8)	2021	34060660
89659	C. parapsilosis	Clinical isolate	ERG11	T504L	Single substitution	G8B9T3	522	AF-G8B9T3-F1		Fluconazole (8)	2021	34060660
ATCC MYA-3404	C. tropicalis	Laboratory strain	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256)	2021	34060660
ATCC MYA-574	C. albicans	Laboratory strain	ERG11	F126L, K128T	Double substitution	P10613	528	5V5Z		Fluconazole (256)	2021	34060660
ATCC64124	C. albicans	Laboratory strain	ERG11 ERG3	Y132H T329S	Single substitution Single substitution	P10613 Q59VG6	528 386	5V5Z AF-Q59VG6-F1		Fluconazole (256)	2021	34060660
ATCC96901	C. albicans	Laboratory strain	ERG11	K128T, K143R	Double substitution	P10613	528	5V5Z	Structure not available	Fluconazole (256)	2021	34060660
I96	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>256)	2021	34060660
K1	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256)	2021	34060660
K2	C. tropicalis	Clinical isolate	ERG11	S154F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256)	2021	34060660
K4	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256)	2021	34060660
K5	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256)	2021	34060660
Ca	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Anidulafungin (1), Caspofungin (8), Micafungin (4)	2021	34064200
Cg	C. glabrata	Clinical isolate	ERG11	I465T, F466S	Double substitution	Q58J63	533	AF-Q58J63-F1	Mismatch residue	AZOLE	2021	34101035
Clade-I	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2021	34176429
Clade-II	C. auris	Clinical isolate	ERG11 FKS1	F126L S639P	Single substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (≥32), Micafungin (≥4)	2021	34176429
Clade-III	C. auris	Clinical isolate	ERG11	E343D, N335S, K177A	Multiple substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (≥32)	2021	34176429
Cd	C. dubliniensis	Clinical isolate	FKS1	S645P	Single substitution	B9W729	1897	Model	Structure not available	Echinocandin	2021	34205349
Cg1	C. glabrata	Clinical isolate	FKS1	F625S	Single substitution	Q6FTN8	1863	Model		Echinocandin	2021	34205349
Cg2	C. glabrata	Clinical isolate	FKS1 FKS2	L630Q S663F	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Echinocandin	2021	34205349
Cg3	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Echinocandin	2021	34205349
Cg4	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Echinocandin	2021	34205349
Cg5	C. glabrata	Clinical isolate	FKS2	L662W	Single substitution	Q6FMZ3	1897	Model		Echinocandin	2021	34205349
Cg6	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Echinocandin	2021	34205349
Cg7	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Echinocandin	2021	34205349
Ck	C. krusei	Clinical isolate	FKS1	S659F	Single substitution	Q4U2W2	1885	Model		Echinocandin	2021	34205349
UMS01	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS08	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.25), Micafungin (0.25)	2021	34340186
UMS27	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS41	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS44	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS46	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS47	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (16), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.25)	2021	34340186
UMS48	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (16), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.25)	2021	34340186
UMS50	C. auris	Environmental source	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (32), Caspofungin (0.5), Anidulafungin (0.5), Micafungin (0.5)	2021	34340186
UMS51	C. auris	Environmental source	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Amphotericin B (2), Fluconazole (16), Caspofungin (0.25), Anidulafungin (0.25), Micafungin (0.5)	2021	34340186
2016-058	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (4), Caspofungin (>8), Fluconazole (>64)	2021	34377983
2016-064	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (4), Caspofungin (>8), Fluconazole (>64)	2021	34377983
2016-144	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	E2GKZ6	1897	Model		Anidulafungin (0.5), Caspofungin (2), Fluconazole (>64)	2021	34377983
2017-041	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (>8), Fluconazole (32)	2021	34377983
2017-252	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Anidulafungin (2), Caspofungin (>8), Fluconazole (64)	2021	34377983
2017-312	C. glabrata	Clinical isolate	FKS2	D666N	Single substitution	E2GKZ6	1897	Model		Anidulafungin (0.125), Caspofungin (0.5), Fluconazole (>64)	2021	34377983
2018-067	C. glabrata	Clinical isolate	FKS1	F625C	Single substitution	E2GKZ3	1863	Model		Anidulafungin (1), Caspofungin (8), Fluconazole (>64)	2021	34377983
2018-462	C. glabrata	Clinical isolate	FKS2	P667T	Single substitution	E2GKZ6	1897	Model		Anidulafungin (0.5), Caspofungin (2), Fluconazole (64)	2021	34377983
2019-615	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	E2GKZ6	1897	Model		Anidulafungin (1), Caspofungin (>8), Fluconazole (32)	2021	34377983
NCU_B011	C. haemulonii	Clinical isolate	ERG11	Y132H	Single substitution	A0A2V1B011	524	AF-A0A2V1B011-F1		Fluconazole (128)Voriconazole (8)	2021	34604110
NCU_B128	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (2), Voriconazole (0.12)	2021	34604110
NCU_B136	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (0.5)	2021	34604110
NCU_B138	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Fluconazole (0.25)	2021	34604110
NCU_B147	C. tropicalis	Clinical isolate	ERG11	S154F, D454N	Double substitution	P14263	528	AF-P14263-F1	Mismatch residue	Fluconazole (2), Voriconazole (0.12)	2021	34604110
NCU_B149	C. albicans	Clinical isolate	ERG11	A114S	Single substitution	P10613	528	5V5Z		Fluconazole (0.25), Voriconazole (≤0.08)	2021	34604110
NCU_B154	C. albicans	Clinical isolate	ERG11	A114S	Single substitution	P10613	528	5V5Z		Fluconazole (0.25), Voriconazole (≤0.08)	2021	34604110
A3	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.25), Itraconazole (1)	2022	34633842
A4	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.25), Itraconazole (1)	2022	34633842
A6	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (0.25), Posaconazole (0.125), Itraconazole (1)	2022	34633842
A7	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (0.25), Posaconazole (0.25), Itraconazole (1)	2022	34633842
A8	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (0.5), Posaconazole (0.25), Itraconazole (1)	2022	34633842
AR-0383	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.125)	2022	34633842
AR-0384	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.25)	2022	34633842
SA1	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.125), Itraconazole (0.25)	2022	34633842
SA10	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.125), Itraconazole (0.5)	2022	34633842
SA11	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (1)	2022	34633842
SA12	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.25)	2022	34633842
SA13	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (8), Voriconazole (1), Itraconazole (0.25)	2022	34633842
SA14	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (2), Itraconazole (0.5)	2022	34633842
SA15	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (8), Voriconazole (1), Itraconazole (0.5)	2022	34633842
SA16	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (8), Voriconazole (1), Itraconazole (0.5)	2022	34633842
SA17	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.25)	2022	34633842
SA18	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (0.5), Itraconazole (0.5)	2022	34633842
SA19	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (2), Itraconazole (0.25)	2022	34633842
SA2	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (0.5), Posaconazole (0.125), Itraconazole (0.5)	2022	34633842
SA22	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128), Voriconazole (0.5), Posaconazole (0.25), Itraconazole (0.5)	2022	34633842
SA23	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (8), Posaconazole (0.25), Itraconazole (0.5)	2022	34633842
SA3	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.5)	2022	34633842
SA4	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.5)	2022	34633842
SA5	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (2), Itraconazole (0.5)	2022	34633842
SA6	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.5)	2022	34633842
SA7	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Posaconazole (0.125), Itraconazole (0.5)	2022	34633842
SA8	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.25)	2022	34633842
SA9	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128), Voriconazole (1), Itraconazole (0.5)	2022	34633842
BMU10720	C. glabrata	Clinical isolate	FKS2 PDR1	S663P P76S, P143T, D243N	Single substitution Multiple substitution	Q6FMZ3 Q66WF3	1897 1107	Model AF-Q66WF3-F1		Posaconazole (4), Itraconazole (2), Caspofungin (32), Micafungin (8), Anidulafungin (4)	2021	34680798
BMU10722	C. glabrata	Clinical isolate	FKS2 PDR1	S663P P76S, P143T, D243N	Single substitution Multiple substitution	Q6FMZ3 Q66WF3	1897 1107	Model AF-Q66WF3-F1		Posaconazole (4), Itraconazole (2), Caspofungin (32), Micafungin (8), Anidulafungin (4)	2021	34680798
NCCPF470197	C. auris	Clinical isolate	FKS1	F635Y	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (16)	2022	34780273
NCCPF470198	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (4), Anidulafungin (4)	2022	34780273
NCCPF470199	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (4), Anidulafungin (4)	2022	34780273
NCCPF470200	C. auris	Clinical isolate	FKS1	R1354S	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (16)	2022	34780273
NCCPF470203	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (2), Anidulafungin (8), Micafungin (16)	2022	34780273
NCCPF470209	C. auris	Clinical isolate	FKS1	F635Y	Single substitution	A0A0L0P0U2	1888	Model		Caspofungin (4)	2022	34780273
AR0390	C. auris	Clinical isolate	ERG11 TAC1	K143R A640V	Single substitution Single substitution	A0A411K953 A0A2H0ZLE8	524 418	AF-A0A411K953-F1 AF-A0A2H0ZLE8-F1		Fluconazole (256)	2021	34878305
AR0390-ERG11k143r	C. auris	Laboratory strain	ERG11	K143R	Single substitution	A0A411K953	524	AF-A0A411K953-F1	Mismatch residue	Fluconazole (128)	2021	34878305
CAGL1256	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (>0.5)	2022	34893830
CAGL1875	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (>0.5)	2022	34893830
Ca1	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), Itraconazole (0.125), Voriconazole (0.5)	2021	34904116
Ca10	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca11	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32), Amphotericin B (>=2)	2021	34904116
Ca12	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32), Amphotericin B (>=2)	2021	34904116
Ca13	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32), Amphotericin B (>=2)	2021	34904116
Ca14	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32)	2021	34904116
Ca2	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), Itraconazole (0.125), Voriconazole (0.5)	2021	34904116
Ca3	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), Itraconazole (0.125), Voriconazole (0.5)	2021	34904116
Ca4	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca5	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca6	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca7	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca8	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ca9	C. auris	Clinical isolate	ERG11	Y132F, K143R	Double substitution	A0A2Z4EHX0	524	AF-A0A2Z4EHX0-F1		Fluconazole (>=32), 5-Flucytosine (>=32)	2021	34904116
Ct	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	AF-P14263-F1		Fluconazole (128), Voriconazole (2)	2021	34904116
isolate2	C. glabrata	Clinical isolate	FKS2	R1377K	Single substitution	E2GKZ6	1897	Model		Micafungin (0.0625), Anidulafungin (0.125)	2021	34976835
isolate3	C. glabrata	Clinical isolate	FKS2	F659del, R1377K	Complex	E2GKZ6	1897	Model	Structure not available	Micafungin (0.25), Anidulafungin (0.5)	2021	34976835
A2	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (8)	2022	35107318
B2	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Micafungin (4), Caspofungin (8)	2022	35107318
patient 3	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64), Itraconazole (1), Voriconazole (0.5)	2022	35140478
10C1B1I1	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Fluconazole	2022	35163552
17-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
19-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
22-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
27-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
28-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
35-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
36-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
40-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
43864	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
43865	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
44-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
47-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
49-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
50-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
51-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
54-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
57-02/20	C. parapsilosis	Clinical isolate	ERG11	R398I	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
63-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
65-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
77-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
81-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
83-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
84-02/20	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole	2022	35205855
AUH-379	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1)	2022	35323941
SSI-2250	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2022	35323941
SSI-3203	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Fluconazole (>32)	2022	35323941
SSI-3775	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2022	35323941
SSI-4843	C. glabrata	Clinical isolate	FKS1 FKS2	L630Q S663F	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Anidulafungin (1)	2022	35323941
SSI-4857	C. glabrata	Clinical isolate	FKS2	L712stop, F659del	Complex	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (4), Fluconazole (>32)	2022	35323941
SSI-5128	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Fluconazole (>32)	2022	35323941
SSI-5324	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (2), Fluconazole (32)	2022	35323941
SSI-6133	C. glabrata	Clinical isolate	FKS2	D663E	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (0.25), Fluconazole (32)	2022	35323941
SSI-7033	C. glabrata	Clinical isolate	FKS2	I662W	Single substitution	Q6FMZ3	1897	Model	Mismatch residue	Anidulafungin (0.5), Fluconazole (>32)	2022	35323941
KW108/18	C. auris	Clinical isolate	ERG11 FKS1	K143R S639T	Single substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>=128), Micafungin (0.125), Anidulafungin (0.25)	2022	35330269
KW3506/17	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=128)	2022	35330269
KW3525/17	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=128)	2022	35330269
KW3584/17	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=128), Itraconazole (1)	2022	35330269
KW60/18	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=128)	2022	35330269
KW87/18	C. auris	Clinical isolate	ERG11 FKS1	K143R S639T	Single substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>=128), Micafungin (0.125), Anidulafungin (0.25)	2022	35330269
KW93/18	C. auris	Clinical isolate	ERG11 FKS1	K143R S639T	Single substitution Single substitution	A0A2H1A309 A0A3G2LW13	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (>=128), Anidulafungin (1), Micafungin (1)	2022	35330269
III.7	C. auris	Clinical isolate	ERG11 MRR1	F126L N647T	Single substitution Single substitution	A0A2H1A309 UMZ08618.1 (NCBI)	524 1133	AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35343781
III.8	C. auris	Clinical isolate	ERG11 MRR1	F126L N647T	Single substitution Single substitution	A0A2H1A309 UMZ08618.1 (NCBI)	524 1133	AF-A0A2H1A309-F1 Model		Fluconazole (512), Voriconazole (2), Itraconazole (4)	2022	35343781
III.9	C. auris	Clinical isolate	ERG11 MRR1	F126L N647T	Single substitution Single substitution	A0A2H1A309 UMZ08618.1 (NCBI)	524 1133	AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35343781
ISOLATE 35	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>=4)	2022	35345665
ISOLATE 37	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (>=4)	2022	35345665
FFUL443	C. glabrata	Clinical isolate	PDR1	S76P, L98S, T143P, I392M	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (2)	2022	35532173
FFUL674	C. glabrata	Clinical isolate	PDR1	L98S, D243N, I803T	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (2)	2022	35532173
FFUL866	C. glabrata	Clinical isolate	PDR1	L98S, D243N, E555K	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1			2022	35532173
ISTA56	C. glabrata	Clinical isolate	PDR1	L98S, D243N, G558C	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (>8)	2022	35532173
ISTB218	C. glabrata	Clinical isolate	PDR1	L98S, D243N	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (4)	2022	35532173
ISTB556	C. glabrata	Clinical isolate	PDR1	L98S, D243N, R376W	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (4)	2022	35532173
ISTB607	C. glabrata	Clinical isolate	PDR1	L98S, D243N, R376W	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (>64), Voriconazole (4)	2022	35532173
10 (United Kingdom)	C. glabrata	Clinical isolate	MSH2 PDR1	P208S, N890I S942F	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
10 (USA)	C. glabrata	Clinical isolate	MSH2 PDR1	P208S, N890I S391L	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
11 (USA)	C. glabrata	Clinical isolate	MSH2 PDR1	A942T, V239L G346S	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
16 (USA)	C. glabrata	Clinical isolate	MSH2 PDR1 PDR1 FKS2 MSH2 PDR1	E231G, L269F R761S T292K F663P E231G, L269F S216R	Double substitution Single substitution Single substitution Single substitution Double substitution Single substitution	Q6FQA9 Q6FXU7 Q6FXU7 Q6FMZ3 Q6FQA9 Q6FXU7	957 1107 1107 1897 957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1 AF-Q6FXU7-F1 Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64) Fluconazole (128), Anidulafungin (1), Caspofungin (0.5), Micafungin (0.5)	2022	35577042
177 (Germany)	C. glabrata	Clinical isolate	PDR1	G334W, E492K, N496S	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
19 (Canada)	C. glabrata	Clinical isolate	PDR1	D554G	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
19 (USA)	C. glabrata	Clinical isolate	FKS2 PDR1 PDR1	S663P N1086Y W297C	Single substitution Single substitution Single substitution	Q6FMZ3 Q6FXU7 Q6FXU7	1897 1107 1107	Model AF-Q6FXU7-F1 AF-Q6FXU7-F1		Fluconazole (128), Anidulafungin (0.25), Micafungin (0.12) Fluconazole (64)	2022	35577042
2 (Germany)	C. glabrata	Clinical isolate	MSH2 PDR1	A942T, V239L A731E	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
2 (Sweden)	C. glabrata	Clinical isolate	MSH2 PDR1	A942T, V239L E369D	Double substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
200 (Korea)	C. glabrata	Clinical isolate	MSH2 PDR1	V239L R956G	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
26 (Korea)	C. glabrata	Clinical isolate	PDR1	E555K	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2022	35577042
26 (USA)	C. glabrata	Clinical isolate	PDR1	G611S, S1048F	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
3 (Spain)	C. glabrata	Clinical isolate	PDR1 PDR1 PDR1	P76S, P143T, D243N, L344S P76S, P143T, D243N, W297L P76S, P143T, D243N, W297L	Multiple substitution Multiple substitution Multiple substitution	Q6FXU7 Q6FXU7 Q6FXU7	1107 1107 1107	AF-Q6FXU7-F1 AF-Q6FXU7-F1 AF-Q6FXU7-F1		Fluconazole (128) Fluconazole (64)	2022	35577042
3 (USA)	C. glabrata	Clinical isolate	FKS2 PDR1 PDR1 PDR1 PDR1	F659del P76S, P143T, D243N P76S, P143T, D243N, G583S P76S, P143T, D243N, S337F P76S, P143T, D243N, S391L	Deletion Multiple substitution Multiple substitution Multiple substitution Multiple substitution	Q6FMZ3 Q6FXU7 Q6FXU7 Q6FXU7 Q6FXU7	1897 1107 1107 1107 1107	Model AF-Q6FXU7-F1 AF-Q6FXU7-F1 AF-Q6FXU7-F1 AF-Q6FXU7-F1		Fluconazole (64), Micafungin (0.25) Fluconazole (64) Fluconazole (128)	2022	35577042
45 (Czech republic)	C. glabrata	Clinical isolate	PDR1	R250K, L280F	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
55 (USA)	C. glabrata	Clinical isolate	PDR1	E259G, G1099S	Double substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
6 (Slovenia)	C. glabrata	Clinical isolate	FKS2 PDR1	F659Y G346D	Single substitution Single substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Fluconazole (128), Anidulafungin (1) Fluconazole (128)	2022	35577042
6 (Spain)	C. glabrata	Clinical isolate	MSH2 PDR1 PDR1	I720T H576Y K778E	Single substitution Single substitution Single substitution	Q6FQA9 Q6FXU7 Q6FXU7	957 1107 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1 AF-Q6FXU7-F1		Fluconazole (128) Fluconazole (64)	2022	35577042
7 (Belgium)	C. glabrata	Clinical isolate	MSH2 PDR1	V239L V329A, T885A	Single substitution Double substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
7 (Ireland)	C. glabrata	Clinical isolate	MSH2 PDR1	V239L N928I	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
7 (Slovenia)	C. glabrata	Clinical isolate	MSH2 PDR1	V239L T1080I	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
7 (USA)	C. glabrata	Clinical isolate	MSH2 PDR1	V239L S316I	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (64)	2022	35577042
8 (USA)	C. glabrata	Clinical isolate	MSH2 PDR1 MSH2	A942T, V239L D554G A942T, V239L	Double substitution Single substitution Double substitution	Q6FQA9 Q6FXU7 Q6FQA9	957 1107 957	AF-Q6FQA9-F1 AF-Q6FXU7-F1 AF-Q6FQA9-F1		Fluconazole (128) Fluconazole (64)	2022	35577042
Cp1	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Cp10	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Cp12	C. parapsilosis	Clinical isolate	MRR1	P255L, A854V	Double substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Cp2	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Cp20	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Cp27	C. parapsilosis	Clinical isolate	MRR1	K129fs, G982R	Complex	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32)	2022	35699442
Cp28	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64)	2022	35699442
Cp29	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64)	2022	35699442
Cp30	C. parapsilosis	Clinical isolate	MRR1	R479K	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64)	2022	35699442
Cp36	C. parapsilosis	Clinical isolate	MRR1	I283R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64)	2022	35699442
Cp39	C. parapsilosis	Clinical isolate	MRR1	G294E	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32)	2022	35699442
Cp9	C. parapsilosis	Clinical isolate	MRR1	A854V	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (16)	2022	35699442
Can Iso–001	C. albicans	Clinical isolate	ERG11	L370S, P375H	Double substitution	P10613	528	5V5Z		Fluconazole (70.2)	2022	35747333
19-4	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639Y	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35770999
19-42	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639P	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35770999
19-43	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639P	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35770999
19-61	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639Y	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256)	2022	35770999
20-15	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R F635C	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-16	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R F635C	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-17	C. auris	Clinical isolate	CDR1 ERG11	V704L K143R	Single substitution Single substitution	A0A2H1A768 A0A2H1A309	1508 524	Model AF-A0A2H1A309-F1		Fluconazole (>256), Anidulafungin (2) [CLSI]	2022	35770999
20-18	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R F635C	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-19	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R F635C	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-20	C. auris	Clinical isolate	CDR1 ERG11	V704L K143R	Single substitution Single substitution	A0A2H1A768 A0A2H1A309	1508 524	Model AF-A0A2H1A309-F1		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-21	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639Y	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (0.5), Micafungin (0.25) [CLSI] Amphotericin B (2) [Etest]	2022	35770999
20-22	C. auris	Clinical isolate	CDR1 ERG11	V704L K143R	Single substitution Single substitution	A0A2H1A768 A0A2H1A309	1508 524	Model AF-A0A2H1A309-F1		Fluconazole (>256), Anidulafungin (0.5), Micafungin (0.25) [CLSI]	2022	35770999
20-23	C. auris	Clinical isolate	CDR1 ERG11	V704L K143R	Single substitution Single substitution	A0A2H1A768 A0A2H1A309	1508 524	Model AF-A0A2H1A309-F1		Fluconazole (>256), Anidulafungin (0.5) [CLSI] Amphotericin B (2) [Etest]	2022	35770999
20-24	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R S639Y	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-25	C. auris	Clinical isolate	CDR1 ERG11 FKS1	V704L K143R F635C	Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H1A4W2	1508 524 1888	Model AF-A0A2H1A309-F1 Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI]	2022	35770999
20-26	C. auris	Clinical isolate	ADE17 CDR1 ERG11 FCY1 FKS1	G45V V704L K143R S70R F635C	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZQ96 A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 A0A2H1A4W2	589 1508 524 150 1888	AF-A0A2H0ZQ96-F1 Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Model		Fluconazole (>256), Posaconazole (1), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI] 5-Flucytosine (>512) [Etest]	2022	35770999
20-27	C. auris	Clinical isolate	CDR1 ERG11 FCY1 FCY2 FKS1	V704L K143R S70R M128fs F635C	Single substitution Single substitution Single substitution Frameshift Single substitution	A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 Not available A0A2H1A4W2	1508 524 150 Not available 1888	Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Not available Model		Fluconazole (>256), Posaconazole (1), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI] 5-Flucytosine (256) [Etest]	2022	35770999
20-28	C. auris	Clinical isolate	CDR1 ERG11 FCY1 FKS1 FUR1	V704L K143R S70R F635C S84L	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 A0A2H1A4W2 A0A0L0P8H5	1508 524 150 1888 218	Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Model AF-A0A0L0P8H5-F1		Fluconazole (>256), Voriconazole (8), Anidulafungin (4), Caspofungin (>16), Micafungin (8) [CLSI] 5-Flucytosine (>512) [Etest]	2022	35770999
20-29	C. auris	Clinical isolate	CDR1 ERG11 FCY1 FCY2 FKS1	V704L K143R S70R M128fs F635C	Single substitution Single substitution Single substitution Frameshift Single substitution	A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 Not available A0A2H1A4W2	1508 524 150 Not available 1888	Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Not available Model		Fluconazole (>256), Anidulafungin (4), Caspofungin (2), Micafungin (4) [CLSI 5-Flucytosine (256) [Etest]	2022	35770999
20-30	C. auris	Clinical isolate	ADE17 CDR1 ERG11 FCY1 FKS1	G45V V704L K143R S70R F635C	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZQ96 A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 A0A2H1A4W2	589 1508 524 150 1888	AF-A0A2H0ZQ96-F1 Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Model		Fluconazole (>256), Voriconazole (8), Isavuconazole (4), Anidulafungin (4), Caspofungin (16), Micafungin (8) [CLSI] 5-Flucytosine (>512) [Etest]	2022	35770999
20-31	C. auris	Clinical isolate	ADE17 CDR1 ERG11 FCY1 FKS1	G45V V704L K143R S70R F635C	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZQ96 A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 A0A2H1A4W2	589 1508 524 150 1888	AF-A0A2H0ZQ96-F1 Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Model		Fluconazole (>256), Voriconazole (16), Isavuconazole (4), Anidulafungin (4), Caspofungin (16), Micafungin (8) [CLSI] Amphotericin B (2), 5-Flucytosine (>512) [Etest]	2022	35770999
20-32	C. auris	Clinical isolate	ADE17 CDR1 ERG11 FCY1 FKS1	G45V V704L K143R S70R F635C	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZQ96 A0A2H1A768 A0A2H1A309 A0A2H0ZDJ1 A0A2H1A4W2	589 1508 524 150 1888	AF-A0A2H0ZQ96-F1 Model AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1 Model		Fluconazole (>256), Voriconazole (8), Isavuconazole (4), Posaconazole (1), Anidulafungin (4), Caspofungin (16), Micafungin (8) [CLSI] Amphotericin B (2), 5-Flucytosine (>512) [Etest]	2022	35770999
20-34	C. auris	Clinical isolate	CDR1 ERG11	V704L K143R	Single substitution Single substitution	A0A2H1A768 A0A2H1A309	1508 524	Model AF-A0A2H1A309-F1		Fluconazole (>256) [CLSI]	2022	35770999
420189	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (128), Voriconazole (4)	2022	35819969
420227	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (128)	2022	35819969
420232	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (32)	2022	35819969
420233	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (32), Voriconazole (1)	2022	35819969
420234	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (64), Voriconazole (1)	2022	35819969
420235	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (32)	2022	35819969
420236	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (32)	2022	35819969
420237	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (64), Voriconazole (1)	2022	35819969
420238	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (256), Voriconazole (16), Itraconazole (16), Posaconazole (2)	2022	35819969
420239	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (256), Voriconazole (16), Itraconazole (16)	2022	35819969
420245	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (128), Voriconazole (2), Itraconazole (1)	2022	35819969
420247	C. tropicalis	Clinical isolate	ERG1 ERG11 UPC2	N74H Y132F, S154F L168P, A251T	Single substitution Double substitution Double substitution	C5MHC9 C5MGS9 C5MAR7	497 528 782	AF-C5MHC9-F1 AF-C5MGS9-F1 AF-C5MAR7-F1		Fluconazole (128), Voriconazole (4), Itraconazole (2)	2022	35819969
ML72254	C. glabrata	Clinical isolate	AUS1 ERG1 PDR1	F1380Y, H35Y P314fs S76P, L98S, T143P	Double substitution Frameshift Multiple substitution	Q6FUR1 O13306 Q6FXU7	1398 489 1107	Model AF-O13306-F1 AF-Q6FXU7-F1		Amphotericin B (>32), Fluconazole (>256), Voriconazole (>32)	2022	35867406
CG1	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Caspofungin (0.75), Fluconazole (>256), Voriconazole (4)	2022	35907476
CG10	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32)	2022	35907476
CG11	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32)	2022	35907476
CG12	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (12), Fluconazole (>256)	2022	35907476
CG2	C. glabrata	Clinical isolate	FKS1 FKS2	R631G S663P	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (>32)	2022	35907476
CG3	C. glabrata	Clinical isolate	FKS1	D632V	Single substitution	Q6FTN8	1863	Model		Caspofungin (2)	2022	35907476
CG4	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1), Fluconazole (>256), Voriconazole (1.5)	2022	35907476
CG5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32), Fluconazole (>256), Voriconazole (1.5)	2022	35907476
CG6	C. glabrata	Clinical isolate	FKS2	S629P	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32)	2022	35907476
CG7	C. glabrata	Clinical isolate	FKS2	F658del	Deletion	Q6FMZ3	1897	Model		Caspofungin (>32)	2022	35907476
CG8	C. glabrata	Clinical isolate	FKS1 FKS2	S629P D666V	Single substitution Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (12), Fluconazole (>256)	2022	35907476
CG9	C. glabrata	Clinical isolate	FKS2	P667H	Single substitution	Q6FMZ3	1897	Model		Caspofungin (>32)	2022	35907476
Cp	C. parapsilosis	Clinical isolate	ERG11	R398I	Single substitution	C7EXA5	522	AF-C7EXA5-F1		MIC90[Fluconazole (64), Voriconazole (2), Itraconazole (0.5)]	2022	35909934
Ct	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		MIC90[Fluconazole (64), Voriconazole (4), Itraconazole (2)]	2022	35909934
1133/P/13-R	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (8), Micafungin (8), Anidulafungin (8), Fluconazole (64), Amphotericin B (8)	2022	35968956
462/P/14	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (4), Micafungin (8), Anidulafungin (8), Fluconazole (64), Amphotericin B (0.5)	2022	35968956
471a/P/14-R	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (8), Micafungin (8), Anidulafungin (8), Fluconazole (64), Amphotericin B (0.5)	2022	35968956
case 1	C. auris	Clinical isolate	ERG11	N335S, E343D	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (16), Voriconazole (0.25), Posaconazole (0.016)	2022	36012776
case 2	C. auris	Clinical isolate	ERG11 FKS1	Y132F, L125F L148I, R937S, I701V, I694V	Double substitution Multiple substitution	A0A2H1A309 A0A2H1A4W2	524 1888	AF-A0A2H1A309-F1 Model		Fluconazole (64), Voriconazole (1), Posaconazole (0.031), Micafungin (0.125), Anidulafungin (0.25)	2022	36012776
case 4	C. auris	Clinical isolate	ERG11 ERG2	L125F, Y132F E39D	Double substitution Single substitution	A0A2H1A309 XP_028888031.1 (NCBI)	524 218	AF-A0A2H1A309-F1 Model		Fluconazole (32), Voriconazole (1), Posaconazole (0.031)	2022	36012776
CPS-C	C. parapsilosis	Clinical isolate	MRR1	G604R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (64), Voriconazole (1)	2022	36028086
MRR1RI	C. parapsilosis	Clinical isolate	MRR1	G604R	Single substitution	G8BAV4	1128	AF-G8BAV4-F1		Fluconazole (32), Voriconazole (1)	2022	36028086
strain 1	C. parapsilosis	Clinical isolate	FKS1 TAC1	E1393G L518F	Single substitution Single substitution	A9YLC3 G8B9R1	1909 980	Model AF-G8B9R1-F1		Fluconazole (8)	2022	36066554
strain 27	C. parapsilosis	Clinical isolate	ERG11 FKS1 TAC1	K143R E1393G L518F	Single substitution Single substitution Single substitution	C7EXA5 A9YLC3 G8B9R1	522 1909 980	AF-C7EXA5-F1 Model AF-G8B9R1-F1		Fluconazole (16)	2022	36066554
strain 33	C. parapsilosis	Clinical isolate	FKS1 TAC1	E1393G L518F	Single substitution Single substitution	A9YLC3 G8B9R1	1909 980	Model AF-G8B9R1-F1		Fluconazole (16)	2022	36066554
strain 40	C. parapsilosis	Clinical isolate	FKS1 TAC1	E1393G L518F	Single substitution Single substitution	A9YLC3 G8B9R1	1909 980	Model AF-G8B9R1-F1		Fluconazole (8)	2022	36066554
strain 51	C. parapsilosis	Clinical isolate	FKS1 TAC1	E1393G L518F	Single substitution Single substitution	A9YLC3 G8B9R1	1909 980	Model AF-G8B9R1-F1		Fluconazole (8)	2022	36066554
strain 7	C. parapsilosis	Clinical isolate	ERG11 FKS1 TAC1	K143R E1393G L518F	Single substitution Single substitution Single substitution	C7EXA5 A9YLC3 G8B9R1	522 1909 980	AF-C7EXA5-F1 Model AF-G8B9R1-F1		Fluconazole (8)	2022	36066554
19-008-0005	C. tropicalis	Clinical isolate	ERG11	Y257H	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (8), Posaconazole (1), Itraconazole (1)	2022	36135621
19-008-0006	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (>8), Posaconazole (2), Itraconazole (>16)	2022	36135621
19-008-0007	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (>8), Posaconazole (1), Itraconazole (1)	2022	36135621
19-008-0008	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (>8), Posaconazole (1), Itraconazole (1)	2022	36135621
19-008-0015	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32), Voriconazole (2)	2022	36135621
19-008-0016	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (8), Posaconazole (1), Itraconazole (4)	2022	36135621
19-008-0017	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (>8), Posaconazole (1), Itraconazole (1)	2022	36135621
19-008-0018	C. tropicalis	Clinical isolate	FKS1	S30P	Single substitution	C5MF18	1280	AF-C5MF18-F1		Micafungin (4), Anidulafungin (0.5_), Caspofungin (4)	2022	36135621
19-008-0045	C. tropicalis	Clinical isolate	ERG11	Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64_), Voriconazole (2)	2022	36135621
19-008-0055	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128), Voriconazole (4)	2022	36135621
19-5326-037-0003	C. tropicalis	Clinical isolate	ERG11	S154F, Y132F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Voriconazole (>8), Posaconazole (0.5), Itraconazole (1)	2022	36135621
SRR11235416	C. tropicalis	Clinical isolate	FKS1	S30P	Single substitution	C5MF18	1280	AF-C5MF18-F1		Micafungin (2), Anidulafungin (1), Caspofungin (8)	2022	36135621
AUH1957	C. parapsilosis	Clinical isolate	FKS1	F652S	Single substitution	A9YLC3	1909	Model		Anidulafungin (>8), Caspofungin (>8), Micafungin (>8), Rezafungin (>8)	2022	36135656
IFRC4050	C. auris	Laboratory strain	ERG11 TAC1	Y132F D599G	Single substitution Single substitution	A0A2H1A309 A0A2H0ZLE8	524 418	AF-A0A2H1A309-F1 AF-A0A2H0ZLE8-F1		Fluconazole (64)	2022	36154919
MRL40	C. auris	Laboratory strain	ERG11	I466L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (64)	2022	36154919
CLE0951	C. catenulata	Clinical isolate	ERG11	Y132F	Single substitution	Not available	Not available	Not available	Structure not available	Fluconazole (16)	2023	36209989
CLE2101	C. catenulata	Clinical isolate	ERG11	Y132F	Single substitution	Not available	Not available	Not available	Structure not available	Fluconazole (256)	2023	36209989
CLE5348	C. catenulata	Clinical isolate	ERG11	Y132F	Single substitution	Not available	Not available	Not available	Structure not available	Fluconazole (256)	2023	36209989
CLE9871-2	C. catenulata	Clinical isolate	ERG11	Y132F	Single substitution	Not available	Not available	Not available	Structure not available	Fluconazole (256)	2023	36209989
ROC2119	C. catenulata	Clinical isolate	ERG11	Y132F	Single substitution	Not available	Not available	Not available	Structure not available	Fluconazole (256)	2023	36209989
SM01	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, G982R	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (64)	2022	36226945
SM05	C. parapsilosis	Clinical isolate	ERG11	Y132F, R398I	Double substitution	G8B9T3	522	AF-G8B9T3-F1	Mismatch residue	Fluconazole (64), Voriconazole (2)	2022	36226945
SM06	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (16)	2022	36226945
SM07	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2022	36226945
SM08	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (1)	2022	36226945
SM10	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (16)	2022	36226945
SM11	C. parapsilosis	Clinical isolate	CDR1	N1132D	Single substitution	G8BJB0	1504	Model		Fluconazole (64), Voriconazole (1)	2022	36226945
SM18	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2022	36226945
SM23	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (2)	2022	36226945
SM24	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (2)	2022	36226945
SM25	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (4)	2022	36226945
SM26	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (2)	2022	36226945
SM27	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (256), Voriconazole (4)	2022	36226945
SM28	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (>256), Voriconazole (4)	2022	36226945
SM29	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (>256), Voriconazole (4)	2022	36226945
SM30	C. parapsilosis	Clinical isolate	CDR1	N1132D	Single substitution	G8BJB0	1504	Model		Fluconazole (16)	2022	36226945
SM32	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (>256), Voriconazole (4)	2022	36226945
SM33	C. parapsilosis	Clinical isolate	CDR1	N1132D	Single substitution	G8BJB0	1504	Model		Fluconazole (32)	2022	36226945
SM36	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N, S614P	Single substitution Double substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (64)	2022	36226945
SM37	C. parapsilosis	Clinical isolate	CDR1	N1132D	Single substitution	G8BJB0	1504	Model		Fluconazole (32)	2022	36226945
Y9-2012	C. parapsilosis	Clinical isolate	ERG11 MRR1	Y132F K177N	Single substitution Single substitution	G8B9T3 G8BAV4	522 1128	AF-G8B9T3-F1 AF-G8BAV4-F1		Fluconazole (8)	2022	36226945
10055	C. glabrata	Clinical isolate	PDR1	R250K	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Voriconazole (1), Posaconazole (2)	2022	36274705
10081	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Fluconazole (8), 5-Flucytosine (>64)	2022	36274705
10116	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Itraconazole (1), Voriconazole (>16), Posaconazole (2)	2022	36274705
10123	C. glabrata	Clinical isolate	PDR1	Y682C	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128), Itraconazole9>8), Voriconazole (4), Posaconazole (>8)	2022	36274705
10573	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
10574	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
10576	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
10578	C. glabrata	Clinical isolate	PDR1	P76S, P143T, D243N	Multiple substitution	Q6FXU7	1107	AF-Q6FXU7-F1	Mismatch residue	Voriconazole (2), Posaconazole (2)	2022	36274705
10582	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32), Voriconazole (2), Posaconazole (2)	2022	36274705
10641	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64), Voriconazole (2), Posaconazole (1)	2022	36274705
10717	C. parapsilosis	Clinical isolate	ERG11	R398I	Single substitution	G8B9T3	522	AF-G8B9T3-F1		Fluconazole (8), Posaconazole (0.5)	2022	36274705
10720	C. glabrata	Clinical isolate	FKS2 PDR1	S663P P76S, P143T, D243N	Single substitution Multiple substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Posaconazole (4), Anidulafungin (4), Micafungin (8), Caspofungin (>16)	2022	36274705
10722	C. glabrata	Clinical isolate	FKS2 PDR1	S663P P76S, P143T, D243N	Single substitution Multiple substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Posaconazole (4), Anidulafungin (4), Micafungin (8), Caspofungin (>16)	2022	36274705
10751	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
10813	C. albicans	Clinical isolate	ERG11	K128T, Y132H, G465S	Multiple substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
10832	C. tropicalis	Clinical isolate	ERG11	S154F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Voriconazole (4), Posaconazole (1)	2022	36274705
10837	C. albicans	Clinical isolate	ERG11	T123I, Y132H	Double substitution	P10613	528	5V5Z		Posaconazole (0.12)	2022	36274705
9956	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>256), Itraconazole (1), Voriconazole (>16), Posaconazole (2)	2022	36274705
9969	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32), Voriconazole (1), Posaconazole (1)	2022	36274705
Taiwan	C. albicans	Clinical isolate	FKS1	S645P	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Micafungin (2)	2022	36286491
USA1	C. glabrata	Clinical isolate	FKS1	D632E	Single substitution	Q6FTN8	1863	Model		Micafungin (0.25)	2022	36286491
USA2	C. glabrata	Clinical isolate	FKS2	R665G	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5), Micafungin (0.25)	2022	36286491
USA3	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2), Micafungin (1)	2022	36286491
USA4	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1), Micafungin (0.5)	2022	36286491
USA5	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4), Micafungin (4)	2022	36286491
USA6	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2), Micafungin (0.5)	2022	36286491
isolarte 141	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), , Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 10	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 116	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (64), Itraconazole (2)], CLSI[Fluconazole (64)]	2022	36294548
isolate 123	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 127	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 147	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (2)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 149	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 150	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 159	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (32)], CLSI[Fluconazole (64)]	2022	36294548
isolate 16	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 17	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (256), Itraconazole (>8)], CLSI[Fluconazole (256)]	2022	36294548
isolate 178	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 19	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 20	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 200	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (256)]	2022	36294548
isolate 23	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8)], CLSI[Fluconazole (64)]	2022	36294548
isolate 233	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 235	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 30	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 4	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F, Y257H	Multiple substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (128), Itraconazole (4)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 41	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (256)]	2022	36294548
isolate 43	C. tropicalis	Clinical isolate	ERG11	K143R	Single substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (64), Itraconazole (2), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (128)]	2022	36294548
isolate 49	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (128), Itraconazole (4)], CLSI[Fluconazole (128)]	2022	36294548
isolate 56	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 64	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 67	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (2), Posaconazole (2)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 68	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 78	C. tropicalis	Clinical isolate	ERG11	K143R	Single substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (64), Itraconazole (1), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (64)]	2022	36294548
isolate 8	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
isolate 84	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (4)]	2022	36294548
isolate99	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		SYO[Fluconazole (>256), Itraconazole (>8), Voriconazole (1), Posaconazole (1)], CLSI[Fluconazole (>256)]	2022	36294548
Cg1	C. glabrata	Clinical isolate	PDR1	E259G	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (64), Voriconazole (1), Posaconazole (2), Itraconazole (2)	2022	36294562
Cg2	C. glabrata	Clinical isolate	PDR1	C469R	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (256), Voriconazole (4), Posaconazole (>8), Itraconazole (>16)	2022	36294562
Cg3	C. glabrata	Clinical isolate	PDR1	F559S	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (128), Voriconazole (2), Posaconazole (>8), Itraconazole (>16)	2022	36294562
Cg4	C. glabrata	Clinical isolate	PDR1	T745A	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (128), Voriconazole (2), Posaconazole (2), Itraconazole (2)	2022	36294562
Cg5	C. glabrata	Clinical isolate	PDR1	E259G	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (64), Voriconazole (1), Posaconazole (2), Itraconazole (1)	2022	36294562
Cg6	C. glabrata	Clinical isolate	PDR1	S942F	Single substitution	Q66WF3	1107	AF-Q66WF3-F1		Fluconazole (128), Voriconazole (4), Posaconazole (>8), Itraconazole (>16)	2022	36294562
Cg7	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	E2GKZ6	1897	Model		Caspofungin (0.5)	2022	36294562
Cp1	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (8)	2022	36294562
Cp2	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64)	2022	36294562
Cp3	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2022	36294562
Cp4	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2022	36294562
Cp5	C. parapsilosis	Clinical isolate	CDR1	N1132D	Single substitution	G8BJB0	1504	Model		Fluconazole (16)	2022	36294562
Cp6	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (4)	2022	36294562
Ct1	C. tropicalis	Clinical isolate	ERG11	Y132F	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2022	36294562
Ct2	C. tropicalis	Clinical isolate	ERG11	Y257H	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (4)	2022	36294562
C. albicans AUH1202	C. albicans	Clinical isolate	FKS1	D1337Y	Single substitution	A0A1D8PCT0	1897	AF-A0A1D8PCT0-F1		Rezafungin (0.125), Micafungin (0.06)	2022	36329639
C. glabrata AUH379	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Rezafungin (0.06), Anidulafungin (1), Micafungin (0.25)	2022	36329639
C. krusei AUH1940	C. krusei	Clinical isolate	FKS1	S659P	Single substitution	Q4U2W2	1885	Model		Rezafungin (0.06), Anidulafungin (0.125), Micafungin (2)	2022	36329639
C. krusei SSI-77.20	C. krusei	Clinical isolate	FKS1	S659P	Single substitution	Q4U2W2	1885	Model		Micafungin (0.5)	2022	36329639
C. parapsilosis AUH1957	C. parapsilosis	Clinical isolate	FKS1	F652S	Single substitution	A9YLC3	1909	Model		Rezafungin (>8), Anidulafungin (>4), Micafungin (>4)	2022	36329639
Ca_1	C. auris	Clinical isolate	FKS1	R1354H	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>2)	2022	36421245
Ca_2	C. auris	Clinical isolate	FKS1	R1354H	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>2)	2022	36421245
Ca_3	C. auris	Clinical isolate	FKS1	S639Y	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>2)	2022	36421245
Ca_4	C. auris	Clinical isolate	FKS1	S639P	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>2)	2022	36421245
TJ1197	C. parapsilosis	Clinical isolate	ERG11 MRR1 FKS1	R398I Y552H S656P	Single substitution Single substitution Single substitution	G8B9T3 G8BAV4 G8B820	522 1128 1909	AF-G8B9T3-F1 AF-G8BAV4-F1 Model		Echinocandin (>8), Fluconazole (>8), Voriconazole (>1)	2023	36440795
Ca2	C. albicans	Clinical isolate	ERG11	E517Q	Single substitution	P10613	528	5V5Z		Fluconazole (>=32)	2022	36654793
Cg1	C. glabrata	Clinical isolate	FKS1	S642L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Fluconazole (>=32)	2022	36654793
Cg2	C. glabrata	Clinical isolate	FKS1	S642L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Fluconazole (>=32), Itraconazole (>=8)	2022	36654793
Cg3	C. glabrata	Clinical isolate	FKS1	S642L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Fluconazole (>=32), Itraconazole (>=8)	2022	36654793
Cg4	C. glabrata	Clinical isolate	FKS1	S642L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Fluconazole (>=32), Itraconazole (>=8)	2022	36654793
Cg5	C. glabrata	Clinical isolate	FKS1	S642L	Single substitution	Q6FTN8	1863	Model	Mismatch residue	Fluconazole (>=32), Caspofungin (4)	2022	36654793
CAS08-0725 (CMD00311)	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Fluconazole (64) Micafungin (0.5) Anidulfungin (2) Amphotericin B (1)	2023	36864040
CAS09-1437 (CGA01045)	C. glabrata	Clinical isolate	FKS1	R631G	Single substitution	Q6FTN8	1863	Model		Fluconazole (64) Micafungin (2) Anidulfungin (1) Amphotericin B (1)	2023	36864040
DPL155 (M234)	C. glabrata	Clinical isolate	FKS2	F659V	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.25) Anidulfungin (1)	2023	36864040
DPL217	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Micafungin (0.5) Anidulfungin (1)	2023	36864040
DPL245 (1611)	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Micafungin (4) Anidulfungin (4)	2023	36864040
DPL274 (3-CPHW20800)	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Micafungin (1) Anidulfungin (4)	2023	36864040
Beijing Chaoyang Hospital	C. tropicalis	Clinical isolate	ERG11 ERG11 ERG11 ERG11	S154F V125A Y132F Y257H	Single substitution Single substitution Single substitution Single substitution	C5MGS9 C5MGS9 C5MGS9 C5MGS9	528 528 528 528	AF-C5MGS9-F1 AF-C5MGS9-F1 AF-C5MGS9-F1 AF-C5MGS9-F1		Fluconazole	2023	36937265
19-45	C. auris	Clinical isolate	FKS1	F635Y	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (4) Caspofungin (16)	2023	36975998
20-16	C. auris	Clinical isolate	FKS1	F635C	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (4) Caspofungin (2) Micafungin (4)	2023	36975998
21-3	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Anidulafungin (4) Micafungin (4)	2023	36975998
CAAL-F	C. albicans	Clinical isolate	ERG11	T220L	Single substitution	Q5I4C6	528	AF-Q5I4C6-F1	Mismatch residue	Voriconazole (32) Fluconazole (128)	2023	37026059
CAAU-A	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (64)	2023	37026059
CAAU-B	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Voriconazole (2) Fluconazole (64)	2023	37026059
CAAU-C	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>128)	2023	37026059
CAAU-F	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Voriconazole (1) Fluconazole (>128)	2023	37026059
CAAU-G	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Voriconazole (8) Fluconazole (>128)	2023	37026059
CAPA-B	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Voriconazole (1) Fluconazole (32)	2023	37026059
CAPA-C	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2023	37026059
CAPA-D	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (32)	2023	37026059
CAPA-E	C. parapsilosis	Clinical isolate	ERG11	K143R	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64)	2023	37026059
CAPA-F	C. parapsilosis	Clinical isolate	ERG11	Y132F	Single substitution	C7EXA5	522	AF-C7EXA5-F1		Fluconazole (64)	2023	37026059
CAS105	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128)	2023	37116861
CAS107	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (128)	2023	37116861
CAS109	C. auris	Clinical isolate	CDR1 CIS2 ERG3 ERG4 ERG5 FKS1 SNQ2 STE6	L1124P K74E E68stop M192I T290T S639F K52N K719N	Single substitution Single substitution Stop Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZWG2 A0A2H0ZLW4 A0A2H0ZNC5 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A4W2 A0A2H1A137 A0A2H0ZW99	1469 625 363 462 517 1888 1486 725	Model AF-A0A2H0ZLW4-F1 AF-A0A2H0ZNC5-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 A0A2H1A4W2 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128) Caspofungin (8) Anidulafungin (8) Micafungin (8)	2023	37116861
CAS111	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (4) Fluconazole (64)	2023	37116861
CAS112	C. auris	Clinical isolate	CIS2 ERG4 ERG5 FKS1 SNQ2 STE6	K74E M192I T290T S639F K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A4W2 A0A2H1A137 A0A2H0ZW99	625 462 517 1888 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 A0A2H1A4W2 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS113	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (4) Fluconazole (64)	2023	37116861
CAS115	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (64)	2023	37116861
CAS116	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (4) Fluconazole (128) Caspofungin (8)	2023	37116861
CAS119	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS120	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (>16) Fluconazole (16)	2023	37116861
CAS121	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Fluconazole (32)	2023	37116861
CAS123	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (64)	2023	37116861
CAS124	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (128)	2023	37116861
CAS126	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (128)	2023	37116861
CAS127	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (4) Fluconazole (32)	2023	37116861
CAS129	C. auris	Clinical isolate	CIS2 ERG4 ERG5 FKS1 SNQ2 STE6	K74E M192I T290T S639F K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A4W2 A0A2H1A137 A0A2H0ZW99	625 462 517 1888 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 A0A2H1A4W2 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (32) Caspofungin (2) Anidulafungin (8) Micafungin (8)	2023	37116861
CAS130	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128)	2023	37116861
CAS131	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128)	2023	37116861
CAS55	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128) Caspofungin (8)	2023	37116861
CAS57	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS58	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS59	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS67	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (64)	2023	37116861
CAS69	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (1) Fluconazole (64)	2023	37116861
CAS73	C. auris	Clinical isolate	CDR1 CIS2 ERG4 ERG5 SNQ2 STE6	L1124P K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZWG2 A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	1469 625 462 517 1486 725	Model AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (8) Fluconazole (32)	2023	37116861
CAS77	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128)	2023	37116861
CAS86	C. auris	Clinical isolate	CDR1 CIS2 ERG4 ERG5 SNQ2 STE6	L1124P K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZWG2 A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	1469 625 462 517 1486 725	Model AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (8) Fluconazole (16)	2023	37116861
CAS87	C. auris	Clinical isolate	CIS2 ERG4 ERG5 SNQ2 STE6	K74E M192I T290T K52N K719N	Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H0ZLW4 A0A2H0ZRG0 A0A2H0ZI96 A0A2H1A137 A0A2H0ZW99	625 462 517 1486 725	AF-A0A2H0ZLW4-F1 AF-A0A2H0ZRG0-F1 AF-A0A2H0ZI96-F1 Model AF-A0A2H0ZW99-F1		Amphotericin B (2) Fluconazole (128)	2023	37116861
ct	C. tropicalis	Clinical isolate	ERG11	Y132F, S154F	Double substitution	P14263	528	Model		Fluconazole	2023	37159900
1923/2021	C. auris	Clinical isolate	FKS1	W691L	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>16) Micafungin (>16) Anidulafungin (2)	2023	37222585
1980/2021	C. auris	Clinical isolate	FKS1	W691L	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>16) Micafungin (>16) Anidulafungin (2)	2023	37222585
1985/2021	C. auris	Clinical isolate	FKS1	W691L	Single substitution	A0A2H1A4W2	1888	Model		Caspofungin (>16) Micafungin (>16) Anidulafungin (16)	2023	37222585
BJCA003	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=128) Amphotericin B (2)	2023	37222986
1	C. glabrata	Clinical isolate	MSH2 PDR1	V239L L825P	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (256) Voriconazole (4) Posaconazole (>8) Itraconazole (>16) Micafungin (0.25)	2023	37233226
10	C. glabrata	Clinical isolate	ERG3 MSH2 PDR1	F226fs V239L L825P	Frameshift Single substitution Single substitution	P50860 Q6FQA9 Q6FXU7	364 957 1107	AF-P50860-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (2) Fluconazole (256) Voriconazole (8) Posaconazole (>8) Caspofungin (0.5) Micafungin (0.5)	2023	37233226
2	C. glabrata	Clinical isolate	FKS1 FKS2 MSH2 PDR1	C499fs I661_L662insF V239L L825P	Frameshift Insertion Single substitution Single substitution	Q6FTN8 Q6FMZ3 Q6FQA9 Q6FXU7	1863 1897 957 1107	Model Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (256) Voriconazole (8) Posaconazole (>8) Itraconazole (>16) Anidulafungin (>8) Caspofungin (>8) Micafungin (0.25P)	2023	37233226
3	C. glabrata	Clinical isolate	ERG6 MSH2 PDR1	A158fs V239L L825P	Frameshift Single substitution Single substitution	Q6FRZ7 Q6FQA9 Q6FXU7	372 957 1107	AF-Q6FRZ7-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (16) Voriconazole (0.5) Micafungin (0.25)	2023	37233226
4	C. glabrata	Clinical isolate	MSH2 PDR1	V239L L825P	Single substitution Single substitution	Q6FQA9 Q6FXU7	957 1107	AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (256) Voriconazole (4) Posaconazole (>8) Itraconazole (>16) Caspofungin (0.25)	2023	37233226
5	C. glabrata	Clinical isolate	FKS1 FKS2 MSH2 PDR1	C499fs I661_L662insF V239L L825P	Frameshift Insertion Single substitution Single substitution	Q6FTN8 Q6FMZ3 Q6FQA9 Q6FXU7	1863 1897 957 1107	Model Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (2) Anidulafungin (>8) Caspofungin (>8) Micafungin (>8)	2023	37233226
6	C. glabrata	Clinical isolate	ERG6 MSH2 PDR1	A158fs V239L L825P	Frameshift Single substitution Single substitution	Q6FRZ7 Q6FQA9 Q6FXU7	372 957 1107	AF-Q6FRZ7-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (8) Voriconazole (0.5) Micafungin (0.25)	2023	37233226
7	C. glabrata	Clinical isolate	ERG6 MSH2 PDR1	A158fs V239L L825P	Frameshift Single substitution Single substitution	Q6FRZ7 Q6FQA9 Q6FXU7	372 957 1107	AF-Q6FRZ7-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (12) Voriconazole (0.5) Micafungin (0.25)	2023	37233226
8	C. glabrata	Clinical isolate	ERG3 ERG4 MSH2 PDR1	G236D P227fs V239L L825P	Single substitution Frameshift Single substitution Single substitution	P50860 Q6FXU8 Q6FQA9 Q6FXU7	364 464 957 1107	AF-P50860-F1 AF-Q6FXU8-F1 AF-Q6FQA9-F1 AF-Q6FXU7-F1		Amphotericin B (3) Fluconazole (>256) Voriconazole (>8) Posaconazole (>8) Itraconazole (>16) Anidulafungin (0.5) Caspofungin (0.5) Micafungin (2)	2023	37233226
9	C. glabrata	Clinical isolate	FKS2 MSH2 PDR1	F659del V239L L825P	Deletion Single substitution Single substitution	Q6FMZ3 Q6FQA9 Q6FXU7	1897 957 1107	Model AF-Q6FQA9-F1 AF-Q6FXU7-F1		Fluconazole (>256) Voriconazole (>8) Posaconazole (>8) Itraconazole (>16) Anidulafungin (2) Caspofungin (>8) Micafungin (1)	2023	37233226
NCPF8985	C. auris	Clinical isolate	FKS1	R1354H	Single substitution	A0A2H1A4W2	1888	A0A2H1A4W2		Caspofungin (8)	2023	37233240
ca	C. albicans	Clinical isolate	CDR2	R683T, L1337F	Double substitution	P78595	1499	AF-P78595-F1		Nystatin (>2)	2023	37233291
Kw 2153/18	C. kefyr	Clinical isolate	ERG3 ERG6	S218P F363L	Single substitution Single substitution	W0T7I0 W0TAZ1	352 375	AF-W0T7I0-F1 AF-W0TAZ1-F1		Etest[Amphotericin B (4) Fluconazole (256) Voriconazole (32) Micafungin (1)], SYO[Amphotericin B (2)]	2024	37358415
Kw 3267/17	C. kefyr	Clinical isolate	ERG2 ERG6	A113S K163Q	Single substitution Single substitution	W0TF99 W0TAZ1	223 375	AF-W0TF99-F1 AF-W0TAZ1-F1		SYO[Amphotericin B (2)]	2024	37358415
Kw 3352/11	C. kefyr	Clinical isolate	ERG2 ERG3	G121C N313S	Single substitution Single substitution	W0TF99 W0T7I0	223 352	AF-W0TF99-F1 AF-W0T7I0-F1		Etest[Amphotericin B (32)], SYO[Amphotericin B (8)]	2024	37358415
Kw135/15	C. kefyr	Clinical isolate	ERG11 ERG2	K151R, Y227D E105K	Double substitution Single substitution	W0TA79 W0TF99	526 223	AF-W0TA79-F1 AF-W0TF99-F1		Etest[Amphotericin B (32) Fluconazole (3)], SYO[Amphotericin B (8) Fluconazole (4)]	2024	37358415
Kw196-11/20	C. kefyr	Clinical isolate	ERG2	L107S	Single substitution	W0TF99	223	AF-W0TF99-F1		Etest[Amphotericin B (32)], SYO[Amphotericin B (2)]	2024	37358415
Kw20-12/20	C. kefyr	Clinical isolate	ERG2 ERG6	G90C F363L	Single substitution Single substitution	W0TF99 W0TAZ1	223 375	AF-W0TF99-F1 AF-W0TAZ1-F1		Etest[Amphotericin B (32)], SYO[Amphotericin B (8)]	2024	37358415
R10	C. albicans	Clinical isolate	TAC1	A736V	Single substitution	Q1WCU6	981	AF-Q1WCU6-F1		Fluconazole (8)	2023	37387494
R11	C. albicans	Clinical isolate	ERG11 TAC1	K143R A736T	Single substitution Single substitution	P10613 Q1WCU6	528 981	5V5Z AF-Q1WCU6-F1		Fluconazole (8)	2023	37387494
R2	C. albicans	Clinical isolate	ERG11	K143R	Single substitution	P10613	528	5V5Z		Fluconazole (>256)	2023	37387494
R3	C. albicans	Clinical isolate	ERG11 TAC1	K143R A736T	Single substitution Single substitution	P10613 Q1WCU6	528 981	5V5Z AF-Q1WCU6-F1		Fluconazole (16)	2023	37387494
R4	C. albicans	Clinical isolate	ERG11 TAC1	K143R A736T	Single substitution Single substitution	P10613 Q1WCU6	528 981	5V5Z AF-Q1WCU6-F1		Fluconazole (16)	2023	37387494
R5	C. albicans	Clinical isolate	ERG11 TAC1	K143R A736T	Single substitution Single substitution	P10613 Q1WCU6	528 981	5V5Z AF-Q1WCU6-F1		Fluconazole (16)	2023	37387494
R6	C. albicans	Clinical isolate	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (16)	2023	37387494
R7	C. albicans	Clinical isolate	TAC1	R673L	Single substitution	Q1WCU6	981	AF-Q1WCU6-F1		Fluconazole (8)	2023	37387494
R9	C. albicans	Clinical isolate	ERG11	F145L	Single substitution	P10613	528	5V5Z		Fluconazole (8)	2023	37387494
D11.1	C. lusitaniae	Clinical isolate	FKS1 RLM1 RPL8B SIP3	L685F N181K A161V D333K	Single substitution Single substitution Single substitution Single substitution	UPI00202CA3AD UPI00202C4402 UPI0012A9C4CE UPI00202BCDCF	1886 420 332 1185	Model AF-A0A5Q0IQS7-F1 Model Model		Micafungin (1)	2023	37428075
D6.1	C. lusitaniae	Clinical isolate	FKS1	R1352C	Single substitution	UPI00202CA3AD	1886	Model		Micafungin (0.25)	2023	37428075
D7.1	C. lusitaniae	Clinical isolate	FKS1 SEC24 SYG1	L1355S T831T E386K	Single substitution Single substitution Single substitution	UPI00202CA3AD C4Y0Z0 UPI0012A91E08	1886 932 912	Model AF-C4Y0Z0-F1 Model		Micafungin (0.25)	2023	37428075
D7.2	C. lusitaniae	Clinical isolate	FKS1	L1355S	Single substitution	UPI00202CA3AD	1886	Model		Micafungin (0.25)	2023	37428075
D8.1	C. lusitaniae	Clinical isolate	FKS1	L1355S	Single substitution	UPI00202CA3AD	1886	Model		Micafungin (0.25)	2023	37428075
D8.2	C. lusitaniae	Clinical isolate	FKS1	L1355S	Single substitution	UPI00202CA3AD	1886	Model		Micafungin (0.25)	2023	37428075
D9.1	C. lusitaniae	Clinical isolate	ERG3	Q308K	Single substitution	C4YAI2	367	AF-C4YAI2-F1		Micafungin (0.25) Fluconazole (2)	2023	37428075
Ch4′r	C. haemulonii	Clinical isolate	FKS1	R1354H	Single substitution	A0A2V1ALV5	1888	Model		Micafungin (>=4) Caspofungin (>=2) Anidulafungin (>=4)	2023	37623630
clade III	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=32)	2023	37735719
clade IV	C. auris	Clinical isolate	ERG11	K177R, N335S, E343D	Multiple substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=32)	2023	37735719
1 (Blood, 2018, E)	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
11 (AR0383)	C. auris	Clinical isolate	ERG11	F126L	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
12 (AR0384)	C. auris	Clinical isolate	ERG11	F126L	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
13 (AR0385)	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
14 (AR0386)	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
16 (AR0388)	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
17 (AR0389)	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole, Amphotericin B	2023	37888235
18 (AR0390)	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H4QC40-F1		Fluconazole	2023	37888235
cgl_107	C. glabrata	Clinical isolate	FKS1 FKS2	Y3D, W929stop S663F	Complex Single substitution	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (1) Micafungin (0.25) Anidulafungin (1)	2023	37974063
cgl_118	C. glabrata	Clinical isolate	FKS1 FKS2	F625del E1117stop	Deletion Stop	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Caspofungin (>8) Micafungin (>8) Anidulafungin (4)	2023	37974063
cgl_123	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2023	37974063
cgl_14	C. glabrata	Clinical isolate	FKS2	R1378H, Q927R	Double substitution	Q6FMZ3	1897	Model		Caspofungin (0.5)	2023	37974063
cgl_178	C. glabrata	Clinical isolate	FKS1 FKS2 ZCF15	G14S F659del, T926P G154N, N189T, A213T, P319H	Single substitution Complex Multiple substitution	Q6FTN8 Q6FMZ3 Q6FTY2	1863 1897 1049	Model Model AF-Q6FTY2-F1		Caspofungin (>8) Micafungin (4) Anidulafungin (4)	2023	37974063
cgl_179	C. glabrata	Clinical isolate	FKS1 FKS2	K1323E Y1825fs	Single substitution Frameshift	Q6FTN8 Q6FMZ3	1863 1897	Model Model		Micafungin (0.5)	2023	37974063
cgl_181	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Caspofungin (2) Micafungin (2) Anidulafungin (1)	2023	37974063
cgl_182	C. glabrata	Clinical isolate	FKS2 ZCF15	S663P M19I	Single substitution Single substitution	Q6FMZ3 Q6FTY2	1897 1049	Model AF-Q6FTY2-F1		Caspofungin (1) Micafungin (1) Anidulafungin (2)	2023	37974063
cgl_183	C. glabrata	Clinical isolate	FKS2	F659C	Single substitution	Q6FMZ3	1897	Model		Caspofungin (1)	2023	37974063
cgl_22	C. glabrata	Clinical isolate	FKS1 FKS2 ZCF15	D632V G1116D Q193fs, S862L	Single substitution Single substitution Complex	Q6FTN8 Q6FMZ3 Q6FTY2	1863 1897 1049	Model Model AF-Q6FTY2-F1		Caspofungin (1) Micafungin (0.5) Anidulafungin (1)	2023	37974063
cgl_37	C. glabrata	Clinical isolate	FKS2	Q12K, S663F	Double substitution	Q6FMZ3	1897	Model		Caspofungin (0.25) Anidulafungin (1)	2023	37974063
cgl_40	C. glabrata	Clinical isolate	FKS2	Q12K, S663F	Double substitution	Q6FMZ3	1897	Model		Caspofungin (1) Micafungin (0.25) Anidulafungin (0.5)	2023	37974063
cgl_88	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (0.5)	2023	37974063
Case 1	C. auris	Clinical	ERG11	F126L	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
Case 2	C. auris	Clinical	ERG11	F126L	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
Case 3	C. auris	Clinical	ERG11	F126L	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
Case 4	C. auris	Clinical	ERG11	F126L	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
Case 5	C. auris	Clinical	ERG11	F126L	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
Case 6	C. auris	Clinical	ERG11	Y132F	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64), Amphotericin B (2)	2024	38164742
Case 7	C. auris	Clinical	ERG11	Y132F	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64), Amphotericin B (2)	2024	38164742
clade I	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64) Amphotericin B (2)	2024	38164742
clade III	C. auris	Clinical isolate	ERG11	V125A, F126L	Double substitution	A0A411K953	524	AF-A0A411K953-F1		Fluconazole (>=64)	2024	38164742
109	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
128	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
15XL	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
26	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
32	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
38	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
53	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
55	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
92-2	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
94	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
99	C. albicans	Clinical isolate	ERG11	K128T	Single substitution	A0A0A0Y2M9	528	AF-A0A0A0Y2M9-F1		Fluconazole (128)	2024	38179314
NRZ-2015-156	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2015-198	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2016-160	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2016-205	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2016-244	C. glabrata	Clinical isolate	FKS2	S663F	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2017-449i	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2017-521	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2017-538	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2018-016	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2018-190	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2018-320	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (4) Ibrexafungerp (>4)	2024	38206004
NRZ-2018-606	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2019-198	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2019-400	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-008	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-260	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-444	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-537f*	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-587	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2020-675	C. glabrata	Clinical isolate	FKS2	F659del	Deletion	Q6FMZ3	1897	Model		Anidulafungin (4) Ibrexafungerp (>4)	2024	38206004
NRZ-2020-780	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0026	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0075	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0255	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0299i	C. glabrata	Clinical isolate	FKS2	F659S	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4) Ibrexafungerp (>4)	2024	38206004
NRZ-2021-0392f*	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0451f*	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0498	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0577	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0737	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2021-0738	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
NRZ-2022-0202	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2)	2024	38206004
CAS08-0725_S45	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) Caspofungin (0.5)	2024	38265207
CAS09-1513_S89	C. glabrata	Clinical isolate	PDR1	R376Q	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (256)	2024	38265207
CAS09_0869_S25	C. glabrata	Clinical isolate	FKS2	F659Y	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) Caspofungin (2)	2024	38265207
CAS10-2227_S31	C. glabrata	Clinical isolate	PDR1	N1091D	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2024	38265207
CAS10-2596_S8	C. glabrata	Clinical isolate	PDR1	G1099S	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (64)	2024	38265207
CAS11-2996_S80	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4) Caspofungin (>16)	2024	38265207
CAS12-3684_S68	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (1) Caspofungin (2)	2024	38265207
CAS12-3743_S58	C. glabrata	Clinical isolate	PDR1	G1079R	Single substitution	Q6FXU7	1107	AF-Q6FXU7-F1		Fluconazole (128)	2024	38265207
CAS12-4416_S11	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2) Caspofungin (2)	2024	38265207
CAS13-4530_S71	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (4) Caspofungin (>16)	2024	38265207
CAS13-4778_S42	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (0.5) Caspofungin (0.5)	2024	38265207
CAS13-5011_S55	C. glabrata	Clinical isolate	FKS2 PDR1	S663P E714D	Single substitution Single substitution	Q6FMZ3 Q6FXU7	1897 1107	Model AF-Q6FXU7-F1		Anidulafungin (2) Caspofungin (8) Fluconazole (64)	2024	38265207
CAS13-5257_S26	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2) Caspofungin (8)	2024	38265207
CAS14-5368_S62	C. glabrata	Clinical isolate	FKS2	S663P	Single substitution	Q6FMZ3	1897	Model		Anidulafungin (2) Caspofungin (8)	2024	38265207
CAS14-5468_S77 21	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2) Caspofungin (4)	2024	38265207
CAS156677_S67	C. glabrata	Clinical isolate	FKS1	S629P	Single substitution	Q6FTN8	1863	Model		Anidulafungin (2) Caspofungin (8)	2024	38265207
clade III	C. auris	Clinical isolate	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	A0A2H1A4W2		Amphotericin B (2) Fluconazole (>64)	2024	38276031
B18580	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (128)	2024	38299868
B18581	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18582	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (128)	2024	38299868
B18583	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18584	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18585	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (128)	2024	38299868
B18587	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18592	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18593	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18594	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (32)	2024	38299868
B18595	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (32)	2024	38299868
B18596	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (256)	2024	38299868
B18597	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18598	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18599	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18600	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (128)	2024	38299868
B18601	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (256)	2024	38299868
B18602	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18603	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18604	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18605	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18606	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18607	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18608	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18609	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18611	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B18612	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (64)	2024	38299868
B18614	C. auris	Clinical isolate	ERG11	F444L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32)	2024	38299868
B20796	C. auris	Clinical isolate	ERG11	K143R	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (128)	2024	38299868
B20798	C. auris	Clinical isolate	ERG11	F444L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32)	2024	38299868
B20799	C. auris	Clinical isolate	ERG11	F444L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32)	2024	38299868
B20800	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20801	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20802	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20803	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20804	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20805	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20806	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20809	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20810	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20811	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20812	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20813	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20814	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20816	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20817	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20820	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20821	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20824	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20825	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20826	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20831	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (256)	2024	38299868
B20835	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20838	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20850	C. auris	Clinical isolate	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	38299868
B20851	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (256)	2024	38299868
B20852	C. auris	Clinical isolate	ERG11	F444L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (32)	2024	38299868
B20855	C. auris	Clinical isolate	ERG11	F444L	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (64)	2024	38299868
B20856	C. auris	Clinical isolate	ERG11 TAC1B	F444L S611P	Single substitution Single substitution	A0A2H1A309 A0A894YV30	524 868	AF-A0A2H1A309-F1 AF-A0A894YV30-F1		Fluconazole (256)	2024	38299868
MIL-ITA-2023	C. auris	Clinical isolate	ERG11 ERG11 FCY1	G54W Y132F S70R	Single substitution Single substitution Single substitution	A0A2H1A309 A0A2H1A309 A0A2H0ZDJ1	524 524 150	AF-A0A2H1A309-F1 AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Posaconazole (>=8) Fluconazole (>=32) 5-Flucytosine (32)	2024	38557967
101008	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101009	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101019	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		CDC[Fluconazole (256) Voriconazole (32)] CLSI-M60[5-Flucytosine (>=64)]	2024	38842332
101022	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101077	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101082	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101087	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
101101	C. auris	Clinical isolate	ERG11 FCY1	Y132F S70R	Single substitution Single substitution	A0A2H1A309 A0A2H0ZDJ1	524 150	AF-A0A2H1A309-F1 AF-A0A2H0ZDJ1-F1		Fluconazole (256) Voriconazole (32)	2024	38842332
CTR12	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (4) Rezafungin (4) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR16	C. tropicalis	Clinical isolate	FKS1	S654P, R1220T	Double substitution	B6S6L8	1904	Model		Anidulafungin (2) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR17	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR18	C. tropicalis	Clinical isolate	FKS1	S654P, G324R	Double substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (2) Fluconazole (128)	2024	38921383
CTR20	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (64)	2024	38921383
CTR21	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR22	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR24	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (0.5) Caspofungin (2) Fluconazole (64)	2024	38921383
CTR25	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (1) Caspofungin (2) Fluconazole (128)	2024	38921383
CTR3	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (64)	2024	38921383
CTR30	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
CTR36	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (1) Rezafungin (2) Caspofungin (4) Fluconazole (64)	2024	38921383
CTR8	C. tropicalis	Clinical isolate	FKS1	S654P	Single substitution	B6S6L8	1904	Model		Anidulafungin (2) Rezafungin (2) Caspofungin (4) Fluconazole (128)	2024	38921383
RICU38 A382	C. auris	Clinical	FKS1	S639P	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (8), Anidulafungin (4)	2024	38989545
RICU40 A430	C. auris	Clinical	FKS1	S639Y	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (2), Anidulafungin (8)	2024	38989545
RICU40 A441	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (2), Anidulafungin (8)	2024	38989545
RICU40 A447	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (2), Anidulafungin (8)	2024	38989545
RICU40 A451	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (2), Anidulafungin (8)	2024	38989545
RICU7 A33	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (4), Anidulafungin (8)	2024	38989545
RICU7 A34	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (4), Anidulafungin (8)	2024	38989545
SICU8 A466	C. auris	Clinical	FKS1	S639P	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (>8), Caspofungin (>8), Anidulafungin (8)	2024	38989545
Y0021	C. auris	Clinical	FKS1	S639F	Single substitution	A0A2H1A4W2	1888	Model		Micafungin (8), Caspofungin (8), Anidulafungin (4)	2024	38989545
R1	C. albicans	Clinical	UPC2	S249K, P259W, Q703L	Multiple substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole, Posaconazole	2024	39059553
R2	C. albicans	Clinical	UPC2	S401R, A446Y	Double substitution	Q59QC7	712	AF-Q59QC7-F1		Fluconazole, Posaconazole	2024	39059553
CJ_3469	C. auris	Clinical	CDR1 CIS2 ERG11 ERG4 FKS1 TAC1	E709D K74E Y132F M192I F635I A583S	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H0ZLW4 A0A2H1A309 A0A2H0ZRG0 A0A2H1A4W2 A0A2H0ZHW2	1508 625 524 462 1888 868	Model AF-A0A2H0ZLW4-F1 AF-A0A2H1A309-F1 AF-A0A2H0ZRG0-F1 Model AF-A0A2H0ZHW2-F1		Fluconazole (>=128), Amphotericin B (>=2), Caspofungin (>=2)	2024	39186218
CJ_4775	C. auris	Clinical	CDR1 CIS2 ERG11 ERG4 FKS1 TAC1	E709D K74E Y132F M192I R1354H A583S	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H0ZLW4 A0A2H1A309 A0A2H0ZRG0 A0A2H1A4W2 A0A2H0ZHW2	1508 625 524 462 1888 868	Model AF-A0A2H0ZLW4-F1 AF-A0A2H1A309-F1 AF-A0A2H0ZRG0-F1 Model AF-A0A2H0ZHW2-F1		Fluconazole (>=128), Amphotericin B (>=2), Caspofungin (>=2)	2024	39186218
CJ_4810	C. auris	Clinical	CDR1 CIS2 ERG11 ERG4 FKS1 TAC1	E709D K74E Y132F M192I W1471L A583S	Single substitution Single substitution Single substitution Single substitution Single substitution Single substitution	A0A2H1A768 A0A2H0ZLW4 A0A2H1A309 A0A2H0ZRG0 A0A2H1A4W2 A0A2H0ZHW2	1508 625 524 462 1888 868	Model AF-A0A2H0ZLW4-F1 AF-A0A2H1A309-F1 AF-A0A2H0ZRG0-F1 Model AF-A0A2H0ZHW2-F1		Fluconazole (>=128), Amphotericin B (>=2), Caspofungin (>=2)	2024	39186218
CA01	C. auris	Clinical	ERG11	Y132F	Single substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (256)	2024	39284275
Clade I	C. auris	Clinical	ERG11	Y132F, K143R	Double substitution	A0A2H1A309	524	AF-A0A2H1A309-F1		Fluconazole (>=32), Amphotericin B (>=2)	2024	39335013
CT1	C. tropicalis	Clinical	ERG11	G464S	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2024	39354378
CT2	C. tropicalis	Clinical	ERG11	G464S	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2024	39354378
CT3	C. tropicalis	Clinical	ERG11	G464S	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (128)	2024	39354378
CT8	C. tropicalis	Clinical	ERG11	G464S	Single substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (256)	2024	39354378
RJ070	C. glabrata	Clinical	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Caspofungin (2)	2024	39435186
RJ097	C. glabrata	Clinical	FKS1 FKS2	S629P W1497stop	Single substitution Stop	E2GKZ4 E2GKZ6	1863 1897	AF-P40989-F1 Model		Caspofungin (>8)	2024	39435186
RJ111	C. glabrata	Clinical	FKS2	S663P	Single substitution	E2GKZ6	1897	Model		Caspofungin (0.5), Fluconazole (64), Voriconazole (2)	2024	39435186
RJ162	C. glabrata	Clinical	FKS2	P667T	Single substitution	E2GKZ6	1897	Model		Caspofungin (1), Fluconazole (64), Voriconazole (2), Itraconazole (>16)	2024	39435186
RJ270	C. glabrata	Clinical	FKS1	S629P	Single substitution	E2GKZ4	1863	AF-P40989-F1		Caspofungin (8)	2024	39435186
YM140066	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64)	2024	39447155
YM140132	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2024	39447155
YM140298	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (8)	2024	39447155
YM140372	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2024	39447155
YM140441	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (32)	2024	39447155
YM140586	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (64)	2024	39447155
YM141055	C. tropicalis	Clinical	ERG11	Y132F, S154F	Double substitution	C5MGS9	528	AF-C5MGS9-F1		Fluconazole (>64)	2024	39447155
Cg20	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg34	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg43	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg48	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg49	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg56	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg57	C. glabrata	Clinical	MSH2	L359S	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg59	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg60	C. glabrata	Clinical	MSH2	V239L, L359S	Double substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg64	C. glabrata	Clinical	MSH2	V239L	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg68	C. glabrata	Clinical	MSH2	P202S	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1	Mismatch residue	Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg83	C. glabrata	Clinical	MSH2	P208S	Single substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg86	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg98	C. glabrata	Clinical	MSH2	V239L, L359S, S431P	Multiple substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
Cg99	C. glabrata	Clinical	MSH2	V239L, S431P	Double substitution	Q6FQA9	957	AF-Q6FQA9-F1		Fluconazole, Itraconazole, Voriconazole	2024	39516859
CP-AR-542	C. parapsilosis	Clinical	ERG11	Y132F	Single substitution	A0A0K1LGA0	522	AF-A0A1A9C770-F1	Structure not available	Fluconazole (256)	2024	39590671
CP-AR-544	C. parapsilosis	Clinical	ERG11	Y132F	Single substitution	A0A0K1LGA0	522	AF-A0A1A9C770-F1	Structure not available	Fluconazole (256)	2024	39590671
ECIFIG1112	C. tropicalis	Clinical	ERG11 TAC1 UPC2	Y132F, S154F N164I A251T, Q289L	Double substitution Single substitution Double substitution	P14263 C5MGV3 C5MAR7	528 943 782	AF-P14263-F1 AF-C5MGV3-F1 AF-C5MAR7-F1		Fluconazole (256), Voriconazole (8)	2024	39641536
ECIFIG1831	C. tropicalis	Clinical	ERG11 TAC1 UPC2	Y132F, S154F N164I A251T, Q289L	Double substitution Single substitution Double substitution	P14263 C5MGV3 C5MAR7	528 943 782	AF-P14263-F1 AF-C5MGV3-F1 AF-C5MAR7-F1		Fluconazole (256), Voriconazole (8)	2024	39641536
ECIFIG21032	C. tropicalis	Clinical	UPC2	A251T, Q289L, T393I	Multiple substitution	C5MAR7	782	AF-C5MAR7-F1		Anidulafungin (1), Micafungin (1), Fluconazole (8)	2024	39641536
ECIFIG685	C. tropicalis	Clinical	ERG11 TAC1 UPC2	Y132F, S154F N164I A251T, Q289L	Double substitution Single substitution Double substitution	P14263 C5MGV3 C5MAR7	528 943 782	AF-P14263-F1 AF-C5MGV3-F1 AF-C5MAR7-F1		Fluconazole (128), Voriconazole (8)	2024	39641536
ECIFIG687	C. tropicalis	Clinical	ERG11 TAC1 UPC2	Y132F, S154F N164I A251T, Q289L	Double substitution Single substitution Double substitution	P14263 C5MGV3 C5MAR7	528 943 782	AF-P14263-F1 AF-C5MGV3-F1 AF-C5MAR7-F1		Fluconazole (256), Voriconazole (8)	2024	39641536
I12	C. albicans	Laboratory strain	ERG11	F105L	Single substitution	P10613	528	5V5Z		Fluconazole (8)	1997	9228762
I4	C. albicans	Laboratory strain	ERG11	F105L	Single substitution	P10613	528	5V5Z		Fluconazole (128)	1997	9228762
I8	C. albicans	Laboratory strain	ERG11	G464S	Single substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (>32), Ketoconazole (16)	1997	9228762
P2	C. albicans	Laboratory strain	ERG11	F105L, G464S	Double substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (>32)	1997	9228762
P3	C. albicans	Laboratory strain	ERG11	F105L	Single substitution	P10613	528	5V5Z		Fluconazole (>256)	1997	9228762
P5	C. albicans	Laboratory strain	ERG11	F105L	Single substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (>32), Ketoconazole (3)	1997	9228762
TU3	C. albicans	Laboratory strain	ERG11	G448E	Single substitution	P10613	528	5V5Z	Structure not available	Fluconazole (>256), Itraconazole (4), Ketoconazole (0.5)	1997	9228762
TU6	C. albicans	Laboratory strain	ERG11	F105L	Single substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (6)	1997	9228762
TU9	C. albicans	Laboratory strain	ERG11	K287R, G464S	Double substitution	P10613	528	5V5Z		Fluconazole (>256), Itraconazole (>32)	1997	9228762
C26	C. albicans	Clinical isolate	ERG11	Y132H, S405F	Double substitution	P10613	528	5V5Z		Fluconazole (>128)	1998	9527767
C39	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (32)	1998	9527767
C40	C. albicans	Clinical isolate	ERG11	Y132H, R467K	Double substitution	P10613	528	5V5Z		Fluconazole (128)	1998	9527767
C56	C. albicans	Clinical isolate	ERG11	G129A, G464S	Double substitution	P10613	528	5V5Z		Fluconazole (128)	1998	9527767
C82	C. albicans	Clinical isolate	ERG11	S405F	Single substitution	P10613	528	5V5Z		Fluconazole (32)	1998	9527767